在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

IL10 Antibody, FITC conjugated

Rare Species
  • 中文名稱:
    IL10兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào):
    CSB-PA011580LC01MOW
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Macaca mulatta IL10 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    IL10Interleukin-10 antibody; IL-10 antibody; Cytokine synthesis inhibitory factor antibody; CSIF antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Macaca mulatta
  • 免疫原:
    Recombinant Macaca mulatta Interleukin-10 protein (19-178AA)
  • 免疫原種屬:
    Macaca mulatta
  • 標(biāo)記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha. Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation. In addition, controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling.
  • 基因功能參考文獻(xiàn):
    1. IL-10 produced during the immune response to malaria in this model contributes to suppression of mucosal inflammatory responses to invasive NTS, which may contribute to differences in the clinical presentation of NTS infection in the setting of malaria. PMID: 24670425
    2. Findings demonstrate that internalization of IL-10R with the resultant impact on IL-10 signaling and dysregulation of the IL-10-mediated anti-inflammatory responses might play a crucial role in epithelial cell damage and subsequent simian immunodeficiency virus pathogenesis. PMID: 25165117
    3. IL-10 plays a crucial role in maintaining mucosal homeostasis by regulating mucosal IFNgamma and TNFalpha cytokine production. PMID: 23867612
  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    IL-10 family
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 九九久久精品国产av片国产| 丰满亚洲大尺度无码无码专线| 未满小14洗澡无码视频网站| 四虎永久在线精品无码视频| 亚洲aⅴ永久无码一区二区三区| 肥白大屁股bbwbbwhd| 国产一区二区三区在线观看免费| 国产手机在线精品| 国产日产精品久久快鸭的功能介绍 | 永久免费观看美女裸体的网站| 亚洲精品suv精品一区二区| 天天爽夜夜爽人人爽免费| 99久久99久久精品国产片果冻 | 亚洲日韩精品一区二区三区无码| 性xxxxx欧美极品少妇| 加勒比东京热无码一区| 无码专区人妻系列日韩精品少妇| 欲色影视天天一区二区三区色香欲 | 亚洲成av人片在线观看下载| 一本色道久久综合无码人妻| 水蜜桃av无码一区二区| 欧洲丰满大乳人妻无码欧美| 精品无码国产一区二区三区av | 人人妻人人澡人人爽国产一区| 亚洲欧洲无码av不卡在线| 亚洲另类色区欧美日韩图片| 久久人妻少妇嫩草av无码专区 | 137裸交肉体摄影| 蜜臀av999无码精品国产专区| 久久精品人妻无码一区二区三区| 久久99精品国产麻豆蜜芽| 无码av在线一本无码| 国产女人18毛片水真多18精品| 中文字幕乱码亚洲精品一区| 无套内谢少妇毛片aaaa片免费| 国产在线视频一区二区三区98 | 国产成_人_综合_亚洲_国产| 国产精品久久人妻无码网站一区 | 韩国精品视频一区二区在线播放| 日韩欧美人妻一区二区三区| 亚洲伊人久久综合成人|