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  4. IARS2 Antibody

IARS2 Antibody

  • 中文名稱：
    IARS2兔多克隆抗體
  • 貨號：
    CSB-PA002995
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of COS7 cells using IARS2 Polyclonal Antibody
    • Western Blot analysis of HELA A549 cells using IARS2 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    IARS2
  • 別名：
    2010002H18Rik antibody; C79125 antibody; EC 6.1.1.5 antibody; FLJ10326 antibody; Iars2 antibody; IleRS antibody; isoleucine tRNA ligase 2, mitochondrial antibody; isoleucine tRNA ligase, mitochondrial antibody; isoleucine tRNA synthetase 2, mitochondrial antibody; Isoleucine--tRNA ligase antibody; isoleucine-tRNA synthetase 2 antibody; isoleucyl tRNA synthetase 2, mitochondrial antibody; Isoleucyl-tRNA synthetase antibody; MGC63429 antibody; mitochondrial antibody; mitochondrial isoleucine tRNA synthetase antibody; rCG_20084 antibody; RGD1311857 antibody; SYIM_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Monkey
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human IARS2.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. IARS2 silencing induced NSCLC cells growth inhibition, cell cycle arrest and promoted cell apoptosis PMID: 26639235
    2. Patients with this very rare mutation present with a myriad of ocular findings, including infantile cataract, neurotrophic keratitis, corneal opacification, and orbital myopathy. PMID: 27078007
    3. The expression of IARS2 gene is different in human colon cancer and surrounding tissues. IARS2 gene is probably a cancer-promoting gene PMID: 26722399
    4. This study is the first report of clinical findings associated with IARS2 mutations. PMID: 25130867
  • 相關疾病：
    Cataracts, growth hormone deficiency, sensory neuropathy, sensorineural hearing loss, and skeletal dysplasia (CAGSSS)
  • 亞細胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Class-I aminoacyl-tRNA synthetase family
  • 數據庫鏈接：

    HGNC: 29685

    OMIM: 612801

    KEGG: hsa:55699

    STRING: 9606.ENSP00000303279

    UniGene: Hs.262823



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