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  4. IARS2 Antibody

IARS2 Antibody

  • 中文名稱：
    IARS2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA229275
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from RAW264.7 cells and COS-7 cells, using IARS2 antibody.
    • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using IARS2 antibody.
    • Immunofluorescence analysis of HepG2 cells, using IARS2 antibody.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) IARS2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    IARS2
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from internal of Human IARS2.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC,IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
    IF 1:100-1:500
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn)：
    1. IARS2 silencing induced NSCLC cells growth inhibition, cell cycle arrest and promoted cell apoptosis PMID: 26639235
    2. Patients with this very rare mutation present with a myriad of ocular findings, including infantile cataract, neurotrophic keratitis, corneal opacification, and orbital myopathy. PMID: 27078007
    3. The expression of IARS2 gene is different in human colon cancer and surrounding tissues. IARS2 gene is probably a cancer-promoting gene PMID: 26722399
    4. This study is the first report of clinical findings associated with IARS2 mutations. PMID: 25130867
  • 相關(guān)疾病：
    Cataracts, growth hormone deficiency, sensory neuropathy, sensorineural hearing loss, and skeletal dysplasia (CAGSSS)
  • 亞細(xì)胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Class-I aminoacyl-tRNA synthetase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29685

    OMIM: 612801

    KEGG: hsa:55699

    STRING: 9606.ENSP00000303279

    UniGene: Hs.262823



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