在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HMGCS2 Antibody, Biotin conjugated

HMGCS2 Antibody, Biotin conjugated

  • 中文名稱：
    HMGCS2兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA010567LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HMGCS2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 (mitochondrial) antibody; 3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 antibody; 3 hydroxy 3 methylglutaryl coenzyme A synthase antibody; 3-hydroxy-3-methylglutaryl coenzyme A synthase antibody; HMCS2_HUMAN antibody; HMG CoA synthase antibody; HMG-CoA synthase antibody; HMGCS 2 antibody; HMGCS2 antibody; Hydroxymethylglutaryl CoA synthase antibody; Hydroxymethylglutaryl CoA synthase mitochondrial antibody; Hydroxymethylglutaryl-CoA synthase antibody; mitochondrial antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Hydroxymethylglutaryl-CoA synthase, mitochondrial protein (426-508AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Catalyzes the first irreversible step in ketogenesis, condensing acetyl-CoA to acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate.
  • 基因功能參考文獻：
    1. several nutrients as well as specific nutritional related hormonal conditions are able to affect significantly HMGCS2 gene expression. PMID: 28888048
    2. miR-107-mediated decrease of HMGCS2 indicates poor outcomes and promotes cell migration in hepatocellular carcinoma PMID: 28867541
    3. this studies demonstrate that HMGCS2 functions as a transcriptional factor that binds to peroxisome proliferator-activated receptor alpha (PPARalpha), resulting in Src expression and activation in a metabolically independent manner PMID: 27816970
    4. HMGCS2 shares with ketone bodies common features in autophagic clearance of APP, suggesting that ketone bodies play an important role in HMGCS2 regulation of the autophagy. PMID: 28320515
    5. High expression of either HSD17B2 or HMGCS2 predicted poor susceptibility of rectal cancer to preoperative chemoradiotherapy. PMID: 25929810
    6. FABP7 and HMGCS2 may have roles in apocrine differentiation categorizing apocrine carcinoma of the breast PMID: 25389781
    7. In Fe-S cluster-deficient muscles, results show a dramatic up-regulation of the ketogenic enzyme HMGCS2 and the secreted protein FGF21 (fibroblast growth factor 21). PMID: 23943793
    8. Human HMGCS2 regulates mitochondrial fatty acid oxidation and FGF21 expression PMID: 21502324
    9. Ketogenesis is an undesirable metabolic characteristic of the proliferating cell, which is down-regulated through c-Myc-mediated repression of the key metabolic gene HMGCS2. PMID: 16940161

    顯示更多

    收起更多

  • 相關(guān)疾病：
    3-hydroxy-3-methylglutaryl-CoA synthase-2 deficiency (HMGCS2D)
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    HMG-CoA synthase family
  • 組織特異性：
    Expression in liver is 200-fold higher than in any other tissue. Low expression in colon, kidney, testis, and pancreas. Very low expression in heart and skeletal muscle. Not detected in brain.; [Isoform 3]: Highest expression detected in heart and skeleta
  • 數(shù)據(jù)庫鏈接：

    HGNC: 5008

    OMIM: 600234

    KEGG: hsa:3158

    STRING: 9606.ENSP00000358414

    UniGene: Hs.59889



主站蜘蛛池模板： 亚洲精品制服丝袜四区| 国产成人精品一区二区三区视频 | 狠狠色婷婷久久一区二区三区| 一边摸一边做爽的视频17国产| 又粗又紧又湿又爽的视频| 国产婷婷丁香五月缴情成人网| 欧美性受xxxx狂喷水| 久久亚洲春色中文字幕久久久 | 日本久久高清一区二区三区毛片 | 999精品无码a片在线1级| 国产精品亚洲综合色区韩国| 国产区图片区小说区亚洲区| 成年轻人电影免费无码| 少妇精油按摩av无码中字| 久久亚洲精品人成综合网| 欧美婷婷六月丁香综合色| 亚洲a成人片在线观看| 美女把尿囗扒开让男人添| 久久综合色_综合色88| 人间精品视频在线播放| 亚洲一区二区三区小说| 日韩欧美成人免费观看| 国产精自产拍在线看中文| 国内乱码一线二线三线| 国产日产人妻精品精品| 国产精品国产三级国产普通话| 日韩av毛片无码免费| 中文无码精品a∨在线| 男人扒开女人腿桶到爽免费| 在线观看无码不卡av| 大j8黑人w巨大888a片| 国产精品爽爽va吃奶在线观看| 久久久久久亚洲精品| 人妻丰满熟妇无码区免费| 日射精情感性色视频| 免费看男女做羞羞的事网站| 亚洲aⅴ天堂av天堂无码麻豆| 小宝贝荡货啊用力水湿aⅴ视频| 国产男生夜间福利免费网站| 成人片黄网站色大片免费毛片| 国产精久久一区二区三区|