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HES7 Antibody

  • 中文名稱:
    HES7兔多克隆抗體
  • 貨號:
    CSB-PA887160LA01HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • IHC image of CSB-PA887160LA01HU diluted at 1:400 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) HES7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HES7
  • 別名:
    bHLH factor Hes7 antibody; bHLHb37 antibody; Class B basic helix loop helix protein 37 antibody; Class B basic helix-loop-helix protein 37 antibody; Hairy and enhancer of split 7 antibody; hes family bHLH transcription factor 7 antibody; Hes7 antibody; HES7_HUMAN antibody; hHes7 antibody; SCDO4 antibody; Transcription factor HES 7 antibody; Transcription factor HES-7 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Transcription factor HES-7 protein (127-192AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated

    本頁面中的產(chǎn)品,HES7 Antibody (CSB-PA887160LA01HU),的標(biāo)記方式是Non-conjugated。對于HES7 Antibody,我們還提供其他標(biāo)記。見下表:

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA887160LB01HU HES7 Antibody, HRP conjugated ELISA
    FITC CSB-PA887160LC01HU HES7 Antibody, FITC conjugated
    Biotin CSB-PA887160LD01HU HES7 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:200-1:500
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation.
  • 基因功能參考文獻(xiàn):
    1. mutation of HES7 is uniquely associated with defects in vertebral, heart and neural tube formation, and this observation will help provide a discriminatory diagnostic guide in patients with SCD, as well as inform molecular genetic testing. PMID: 23897666
    2. MESP2, HES7 and DUSP6 genes may not be involved in the etiopathogenesis of sporadic and non-syndromic CS in Chinese Han population. PMID: 22744456
    3. Two new missense mutations in HES7 in a family with spondylocostal dysostosis. PMID: 20087400
    4. R25W missense mutation of HES7 is causative of Spondylocostal dysostosis. PMID: 18775957
  • 相關(guān)疾病:
    Spondylocostal dysostosis 4, autosomal recessive (SCDO4)
  • 亞細(xì)胞定位:
    Nucleus.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 15977

    OMIM: 608059

    KEGG: hsa:84667

    STRING: 9606.ENSP00000446205

    UniGene: Hs.434828



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