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  4. HES7 Antibody, Biotin conjugated

HES7 Antibody, Biotin conjugated

  • 中文名稱：
    HES7兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA887160LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HES7 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HES7
  • 別名：
    bHLH factor Hes7 antibody; bHLHb37 antibody; Class B basic helix loop helix protein 37 antibody; Class B basic helix-loop-helix protein 37 antibody; Hairy and enhancer of split 7 antibody; hes family bHLH transcription factor 7 antibody; Hes7 antibody; HES7_HUMAN antibody; hHes7 antibody; SCDO4 antibody; Transcription factor HES 7 antibody; Transcription factor HES-7 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Transcription factor HES-7 protein (127-192AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation.
  • 基因功能參考文獻：
    1. mutation of HES7 is uniquely associated with defects in vertebral, heart and neural tube formation, and this observation will help provide a discriminatory diagnostic guide in patients with SCD, as well as inform molecular genetic testing. PMID: 23897666
    2. MESP2, HES7 and DUSP6 genes may not be involved in the etiopathogenesis of sporadic and non-syndromic CS in Chinese Han population. PMID: 22744456
    3. Two new missense mutations in HES7 in a family with spondylocostal dysostosis. PMID: 20087400
    4. R25W missense mutation of HES7 is causative of Spondylocostal dysostosis. PMID: 18775957
  • 相關疾病：
    Spondylocostal dysostosis 4, autosomal recessive (SCDO4)
  • 亞細胞定位：
    Nucleus.
  • 數據庫鏈接：

    HGNC: 15977

    OMIM: 608059

    KEGG: hsa:84667

    STRING: 9606.ENSP00000446205

    UniGene: Hs.434828



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