在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HES5 Antibody

HES5 Antibody

  • 中文名稱：
    HES5兔多克隆抗體
  • 貨號(hào)：
    CSB-PA041972
  • 規(guī)格：
    ￥1100
  • 圖片：
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Mouse skin tissue, human fetal liver tissue, Human fetal brain tissue, Primary antibody: CSB-PA041972(HES5 Antibody) at dilution 1/100, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    bHLHb38 antibody; Class B basic helix-loop-helix protein 38 antibody; Hairy and enhancer of split 5 antibody; Hairy/Enhancer of spli, Drosophila, homolog of, 5 antibody; HES 5 antibody; hes family bHLH transcription factor 5 antibody; Hes5 antibody; HES5 protein antibody; HES5_HUMAN antibody; MGI:104876 antibody; Transcription factor HES-5 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human HES5
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Transcriptional repressor of genes that require a bHLH protein for their transcription. Plays an important role as neurogenesis negative regulator.
  • 基因功能參考文獻(xiàn)：
    1. HES5 might contribute to the proliferation of non-small cell lung cancer by STAT3 signaling. PMID: 27878283
    2. that suppression of the HES5 leading to inhibition of proliferation may be one of the mechanisms against Hepatocellular carcinoma PMID: 26342546
    3. HES5 silencing is an early and recurrent change in prostate tumourigenesis PMID: 25560400
    4. these data identify HES5 as a key mediator of the Wnt-3a proneurogenic effect occurring independently of the classical Wnt/beta-catenin signaling cascade thus further deciphering crosstalk mechanisms of Wnt and Notch signaling pathways regulating cell fate PMID: 24548083
    5. the downstream Notch signalling effector HES5 directly represses transcription of the E3 ligase Fbw7beta. PMID: 23776410
    6. Notch3 and Hes5 are hypermethylated in human B cell acute lymphoblastic leukemia (ALL). PMID: 23637910
    7. Hes5 overactivation is associated with cell differentiation, thereby resulting in uterine carcinogenesis. PMID: 21495212
    8. In this study, HES 5 transcription factor was detected in the lining epithelium of human periapical cysts with limited inflammation, showing Notch pathway activation in those cells. PMID: 21238798
    9. The expression of HES5 in adenocarcinoma was significantly higher than those in adenoma and normal control PMID: 20091184
    10. For marking and purifying neural stem cells to ascertain whether differences exist, we generated transgenic mice using promoters from Hes genes (pHes1 or pHes5) to drive expression of destabilized enhanced green fluorescent protein. PMID: 16214363
    11. Notch protein binding to Hes5-GFP is extinguished fast and recovered slowly, whereas Hes1-GFP is inhibited late and recovered quickly PMID: 16365048
    12. The HLH gene HES5 on the other hand was only detected in chondrocytes. PMID: 17072841
    13. Human HES5 gene is coupled to the Notch receptor family and expression of Notch markers (including HES5) decreases during cartilage differentiation. PMID: 17093926
    14. expression significantly higher in squamous cervical carcinoma than in CIN as well as higher in CIN than normal cervical epithelia PMID: 17388915
    15. Data show that HES5 are abundantly expressed in osteoarthritis. PMID: 18354251
    16. regulates brain development process.[review] PMID: 18524252

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 組織特異性：
    Expressed in fetal heart and brain tumors.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19764

    OMIM: 607348

    KEGG: hsa:388585

    STRING: 9606.ENSP00000367714

    UniGene: Hs.57971



主站蜘蛛池模板： 精品国产亚洲午夜精品av | 精品午夜福利1000在线观看| 精品无码午夜福利理论片| 性荡视频播放在线视频| 亚洲精品国产精品国产自2022| 午夜福利视频一区二区手机免费看| 三级男人添奶爽爽爽视频 | 欧美最猛性xxxxx免费| 亚洲国产精品国语在线| 国产午夜片无码区在线观看爱情网| 日本日本熟妇中文在线视频| 国产又大又硬又粗| 成人欧美一区二区三区在线观看| 日产无码中文字幕av| av激情亚洲男人的天堂| 真实国产熟睡乱子伦视频| 国产av丝袜旗袍无码网站| 亚洲va久久久噜噜噜久久狠狠| 播五月开心婷婷欧美综合| 国产精品亚洲a∨天堂| 亚洲国产欧美在线观看| 男女超爽视频免费播放| 无线日本视频精品| 亚洲精品久久久久午夜福利 | 欧美v国产v亚洲v日韩九九| 麻豆av字幕无码中文| 亚洲另类欧美综合久久图片区| 亚洲情综合五月天| 天堂资源中文网| 九色精品国产成人综合网站| 亚洲熟妇无码av不卡在线播放| 无码137片内射在线影院| 97影院理论午夜伦不卡| av不卡国产在线观看| 亚洲 日本 欧美 中文幕| 高潮添下面视频免费看| 日韩人妻无码精品系列| 欧美色欧美亚洲高清在线视频| 久久久性色精品国产免费观看| 日本免费一区二区三区日本| 亚洲精品国产av成拍色拍婷婷|