在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HES5 Antibody, Biotin conjugated

HES5 Antibody, Biotin conjugated

  • 中文名稱：
    HES5兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA729212LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) HES5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    bHLHb38 antibody; Class B basic helix-loop-helix protein 38 antibody; Hairy and enhancer of split 5 antibody; Hairy/Enhancer of spli, Drosophila, homolog of, 5 antibody; HES 5 antibody; hes family bHLH transcription factor 5 antibody; Hes5 antibody; HES5 protein antibody; HES5_HUMAN antibody; MGI:104876 antibody; Transcription factor HES-5 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Transcription factor HES-5 protein (1-166AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Transcriptional repressor of genes that require a bHLH protein for their transcription. Plays an important role as neurogenesis negative regulator.
  • 基因功能參考文獻(xiàn)：
    1. HES5 might contribute to the proliferation of non-small cell lung cancer by STAT3 signaling. PMID: 27878283
    2. that suppression of the HES5 leading to inhibition of proliferation may be one of the mechanisms against Hepatocellular carcinoma PMID: 26342546
    3. HES5 silencing is an early and recurrent change in prostate tumourigenesis PMID: 25560400
    4. these data identify HES5 as a key mediator of the Wnt-3a proneurogenic effect occurring independently of the classical Wnt/beta-catenin signaling cascade thus further deciphering crosstalk mechanisms of Wnt and Notch signaling pathways regulating cell fate PMID: 24548083
    5. the downstream Notch signalling effector HES5 directly represses transcription of the E3 ligase Fbw7beta. PMID: 23776410
    6. Notch3 and Hes5 are hypermethylated in human B cell acute lymphoblastic leukemia (ALL). PMID: 23637910
    7. Hes5 overactivation is associated with cell differentiation, thereby resulting in uterine carcinogenesis. PMID: 21495212
    8. In this study, HES 5 transcription factor was detected in the lining epithelium of human periapical cysts with limited inflammation, showing Notch pathway activation in those cells. PMID: 21238798
    9. The expression of HES5 in adenocarcinoma was significantly higher than those in adenoma and normal control PMID: 20091184
    10. For marking and purifying neural stem cells to ascertain whether differences exist, we generated transgenic mice using promoters from Hes genes (pHes1 or pHes5) to drive expression of destabilized enhanced green fluorescent protein. PMID: 16214363
    11. Notch protein binding to Hes5-GFP is extinguished fast and recovered slowly, whereas Hes1-GFP is inhibited late and recovered quickly PMID: 16365048
    12. The HLH gene HES5 on the other hand was only detected in chondrocytes. PMID: 17072841
    13. Human HES5 gene is coupled to the Notch receptor family and expression of Notch markers (including HES5) decreases during cartilage differentiation. PMID: 17093926
    14. expression significantly higher in squamous cervical carcinoma than in CIN as well as higher in CIN than normal cervical epithelia PMID: 17388915
    15. Data show that HES5 are abundantly expressed in osteoarthritis. PMID: 18354251
    16. regulates brain development process.[review] PMID: 18524252

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 組織特異性：
    Expressed in fetal heart and brain tumors.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 19764

    OMIM: 607348

    KEGG: hsa:388585

    STRING: 9606.ENSP00000367714

    UniGene: Hs.57971



主站蜘蛛池模板： 中文精品久久久久鬼色| 亚洲中文字幕码在线电影| 亚洲一卡一卡二新区迎热烈讨论| 黑人巨大av无码专区| 色狠狠av老熟女| 337p西西人体大胆瓣开下部| 精品国产你懂的在线观看| 国产在线乱子伦一区二区| 亚洲熟妇少妇任你躁在线观看无码 | 50路60路老熟妇啪啪| 全免费又大粗又黄又爽少妇片| 国产精品186在线观看在线播放| 天美传媒精品1区2区3区| 国产成人精品精品日本亚洲| 青青草原亚洲| 狠狠色综合7777久夜色撩人| 亚洲vav在线男人的天堂| 图片区小说区另类春色| 最新高清无码专区| 中文字幕日韩精品无码内射| 国产激情无码一区二区app| 免费国产在线精品一区二区三区| 国产日韩在线时看高清视频 | 狠狠狠狼鲁亚洲综合网| 黄页网站在线观看免费视频| 人人莫人人擦人人看| 精品国产亚洲一区二区三区| 成人性做爰aaa片免费看| 色一情一乱一乱一区99av| 亚洲午夜久久久精品影院| 国产成人亚洲综合无码精品| 在线播放国产不卡免费视频| 波多野结衣av高清一区二区三区| 中文字幕 制服 亚洲 另类| 色播亚洲视频在线观看| 国产精品欧美成人片| 丰满大肥婆肥奶大屁股| 国产精品毛片a∨一区二区三区 | 日本中文字幕亚洲乱码| 成人综合网站| 18禁美女黄网站色大片免费网站|