在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. HELLS Antibody

HELLS Antibody

  • 中文名稱：
    HELLS兔多克隆抗體
  • 貨號：
    CSB-PA868307HA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA868307HA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA868307HA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HELLS Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HELLS
  • 別名：
    FLJ10339 antibody; Helicase lymphoid specific antibody; Hells antibody; HELLS_HUMAN antibody; LSH antibody; Lymphoid specific helicase antibody; Lymphoid-specific helicase antibody; Nbla10143 antibody; PASG antibody; Proliferation associated SNF2 like protein antibody; Proliferation-associated SNF2-like protein antibody; SWI/SNF2 related matrix associated actin dependent regulator of chromatin subfamily A member 6 antibody; SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Lymphoid-specific helicase protein (550-600AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，HELLS Antibody (CSB-PA868307HA01HU)，的標記方式是Non-conjugated。對于HELLS Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA868307HB01HU HELLS Antibody, HRP conjugated ELISA
    FITC CSB-PA868307HC01HU HELLS Antibody, FITC conjugated
    Biotin CSB-PA868307HD01HU HELLS Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis.
  • 基因功能參考文獻：
    1. HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex; immunodeficiency-centromeric instability-facial anomalies syndrome has a defective HELLS and CDCA7 bipartite nucleosome remodeling complex PMID: 29339483
    2. This study elucidates the molecular basis of the c-Myc/EGLN1-mediated induction of LSH expression that inhibits ferroptosis PMID: 28900510
    3. LSH is likely one of the mechanisms of genome instability underlying 5-hydroxymethylcytosine loss in cancer. PMID: 29109788
    4. High mRNA levels of HELLS is independent predictor of poor outcome in Renal Cell Carcinoma patients. PMID: 28069330
    5. Mutations in HELLS cause immunodeficiency-centromeric instability-facial anomalies syndrome type 4. PMID: 26216346
    6. Mutations of HELLS gene is associated with stomach and colorectal cancers. PMID: 25351940
    7. Upregulation of HELLS and UHRF1 is essential for the tumor phenotype. Also, these epigenetic regulators are important for the regulation of SYK. PMID: 25338120
    8. just as E2F3, HELLS is overexpressed in human tumours including prostate cancer, indicating that either factor may contribute to the malignant progression of tumours PMID: 22157815
    9. E2F1 plays a crucial role in transcriptional control of the human Lsh gene and the decrease of Lsh expression in senescent cells is related to the repression of E2F1 PMID: 21453717
    10. Data provide strong evidence that CEP55 and HELLS may be used in conjunction with FOXM1 as a biomarker set for early cancer detection and indicators of malignant conversion and progression. PMID: 20400365
    11. LSH serves as a recruiting factor for DNA methyltransferases and histone deacetylases to establish transcriptionally repressive chromatin which is perhaps further stabilized by DNA methylation at targeted loci PMID: 17967891
    12. These results suggest differences in cellular consequences of hypomethylation mediated by PASG during development compared to that in somatic cells. PMID: 18948754
    13. Lsh overexpression delays cell senescence by silencing p16(INK4a) in human fibroblasts. PMID: 19561196

    顯示更多

    收起更多

  • 相關疾病：
    Immunodeficiency-centromeric instability-facial anomalies syndrome 4 (ICF4)
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    SNF2/RAD54 helicase family
  • 組織特異性：
    Highly expressed in proliferative tissues such as adult thymus and testis, and expressed at lower levels in uterus, small intestine, colon, and peripheral blood mononuclear cells. Also expressed in neoplastic cell lines including those derived from myeloi
  • 數據庫鏈接：

    HGNC: 4861

    OMIM: 603946

    KEGG: hsa:3070

    STRING: 9606.ENSP00000239027

    UniGene: Hs.463677



主站蜘蛛池模板： 亚洲另类激情综合偷自拍图片| 人与嘼交av免费| 免费人成视频x8x8入口| 久久亚洲美女精品国产精品 | 很黄很色60分钟在线观看| 久久精品www人人爽人人| 久久人人爽人人爽人人片| 无码一区二区三区亚洲人妻| 亚洲综合一区无码精品| 巨胸喷奶水视频www免费网站| 玩弄了裸睡少妇人妻野战| 日本少妇xxxx做受| 午夜福利伦伦电影理论片在线观看 | 亚洲欧美韩国综合色| 国产色欲色欱www在线| 国内偷窥一区二区三区视频| 国产尤物精品自在拍视频首页| 久久亚洲精品国产亚洲老地址 | 国产a线视频播放| 成人国产一区二区三区精品| 少妇高潮大叫好爽| 偷拍区清纯另类丝袜美腿| 亚洲制服丝袜av一区二区三区| 亚洲一卡2卡3卡4卡5卡精品 | 亚洲中文字幕无码人在线| 亚洲精品无码av人在线观看国产| 亚洲 丝袜 另类 校园 欧美| 国产va在线观看免费| 亚洲色欲天天天堂色欲网| 日本 精品 高清不卡| 欧美不卡一区二区三区| 色先锋资源久久综合5566| 私人家庭影院5777| 日本爽爽爽爽爽爽在线观看免 | 刺激性视频黄页| 蜜芽av无码精品国产午夜| 少妇高潮太爽了在线视频| 成人欧美一区二区三区1314| 精品aⅴ一区二区三区| 午夜无码成人免费视频| 国产精品9999久久久久仙踪林|