在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

HDC Antibody, HRP conjugated

  • 中文名稱:
    HDC兔多克隆抗體, HRP偶聯(lián)
  • 貨號:
    CSB-PA13409B0Rb
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) HDC Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    HDC
  • 別名:
    DCHS_HUMAN antibody; EC 4.1.1.22 antibody; HDC antibody; Histidine decarboxylase antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Histidine decarboxylase protein (504-648AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Catalyzes the biosynthesis of histamine from histidine.
  • 基因功能參考文獻:
    1. Human histidine decarboxylase (HDC) and dopa decarboxilase (DDC) are highly homologous enzymes responsible for the synthesis of biogenic amines (BA) like histamine, and serotonin and dopamine, respectively. This review summarizes the analogies and differences in their origin as well as their common pathophysiological scenarios. [review] PMID: 27769832
    2. a Possible Role for the Histidine Decarboxylase Gene in Tourette Syndrome in the Chinese Han Population PMID: 27529419
    3. Human enterochromaffin-like cells appear to partially co-express VMAT-2 and HDC. Co-expression of VMAT-2 and HDC might be required for increased histamine production in patients with gastric neuroendocrine tumors. PMID: 26715806
    4. The findings indicate that polymorphisms of HDC gene were significantly associated with breast cancer in Chinese Han population and may be novel diagnostic or therapeutic targets for breast cancer. PMID: 24835231
    5. HDC rs17740607 polymorphism is at least a partial loss-of-function variant and acts as a protective factor against chronic heart failure PMID: 25846768
    6. Investigated variation across the HDC (histidine decarboxylase) gene for association with Tourette Syndrome. PMID: 23825391
    7. HDC production in the stomach is associated with bile acid exposure and its related transcriptional regulation network of FXR, SHP, and CDX1. PMID: 24415870
    8. Data indicate that histidine decarboxylase (HDC) is expressed by neutrophils. PMID: 23572231
    9. Structural study reveals that Ser-354 determines substrate specificity on human histidine decarboxylase. PMID: 22767596
    10. crystal of histidine decarboxylase belonged to space group C2, with unit-cell parameters a = 215.16, b = 112.72, c = 171.39 A, beta = 110.3 degrees PMID: 22684068
    11. It was shown that for serum and urine, HDC levels achieved sensitivities and specificities compatible to or even greater than those of established biomarkers for the diagnosis of intestinal mucosal injury in patients with acute intestinal obstruction. PMID: 21915437
    12. The novel concept that an autocrine loop, consisting of enhanced histamine synthesis by histidine decarboxylase, sustains cholangiocarcinoma growth is proposed. PMID: 21873469
    13. Variants in the HDC gene may play little or no role in Tourette Syndrome susceptibility in Chinese Han population. PMID: 22095709
    14. Studies provide lead compounds for inhibitors of ornithine decarboxylase and human histidine decarboxylase. PMID: 21454364
    15. The histidine decarboxylase allele Glu644 in homozygosity increases the risk of developing rhinitis in the studied population PMID: 20608921
    16. identification of a rare functional mutation in the HDC gene encoding L-histidine decarboxylase, the rate-limiting enzyme in histamine biosynthesis which points to its role in Tourette's syndrome and tics PMID: 20445167
    17. the elevation of HDC expression during human monocytic differentiation PMID: 11556524
    18. HDC expression is regulated by gastrin through a complex cis-acting element, which binds at least three distinct nuclear factors PMID: 12372397
    19. Histidine decarboxylase promoter activity can be repressed by kruppel-like factor 4 PMID: 14670968
    20. histidine decarboxylase mRNA is found in human vascular smooth muscle and endothelial cells PMID: 15167966
    21. HDC and histamine content were significantly higher in the tumor specimens PMID: 15928846
    22. Chronic urticaria expresses high levels of HDC as compared to normal foreskin, breast skin and cultured human keratinocytes. PMID: 16297195
    23. HDC expression and histamine production are increased in the superficial kidney cortex zone during pregnancy PMID: 16760908
    24. Defective levels found in normal placenta compared with pre-eclampsia labor. PMID: 16822545
    25. Synthesis of histamine was found to be restricted to the basophil compartment of the CML clone and to depend on signaling through the PI3-kinase pathway. CML cells also expressed histamine receptors PMID: 16849647
    26. HDC SNP's are significantly associated with age at natural menopause in Caucasian women. PMID: 16919600
    27. Histamine decarboxylase expressed in endothelial cells of microvessels might play a role in regulating angiogenesis in esophageal squamous cell carcinomas. PMID: 19133005
    28. HFR was regulated by HIF-1 activation. Depletion of HIF-1alpha prevents hypoxic induction of HDC in BMMCs. Hypoxia induces HDC expression by transcriptional mechanisms dependent upon HIF-1. PMID: 19266161
    29. the apparent occurrence of an unusual TG 3' splice site in intron 4 is discussed PMID: 17672918

    顯示更多

    收起更多

  • 蛋白家族:
    Group II decarboxylase family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 4855

    OMIM: 142704

    KEGG: hsa:3067

    STRING: 9606.ENSP00000267845

    UniGene: Hs.1481



主站蜘蛛池模板: 国产精品久久无码一区| 亚洲精品无码久久久久av麻豆| 欧美白丰满老太aaa片| 久久久久人妻精品一区三寸蜜桃| 大伊香蕉精品视频在线天堂| 欧美v亚洲v日韩v最新在线| 麻豆精品一卡二卡三卡| 18禁无遮挡羞羞污污污污网站| 国产精品美女久久久久av爽| 影音先锋女人aa鲁色资源| 亚洲337少妇裸体艺术| 亚洲日韩看片无码超清| 天堂中文官网在线| 亚洲人亚洲精品成人网站| 欲求不满邻居的爆乳在线播放| 日本丰满护士爆乳xxxx| 天天躁夜夜躁狠狠是什么心态| 亚洲国产成人一区二区精品区 | 日日碰狠狠躁久久躁综合小说 | 精品日产卡一卡二卡麻豆| 精品无码久久久久久尤物| 亚洲最大av资源站无码av网址| 老太脱裤子让老头玩xxxxx| 男女啪啪免费观看的网址| 中文字幕乱码熟妇五十中出色欲| 人妻体内射精一区二区三区| 亚洲精品国产成人99久久6| 欧洲精品无码一区二区三区在线播放| 大胸少妇午夜三级| 久久无码人妻丰满熟妇区毛片| 久久久久久妓女精品影院| 亚洲欧美午夜理论电影在线观看| 毛多水多www偷窥小便| 国产精品igao视频网| 色欲来吧来吧天天综合网| 日本人与黑人做爰视频网站| 加勒比一本heyzo高清视频| 日本妇人成熟免费中文字幕| 日本少妇自慰免费完整版| 亚洲欧美中文日韩在线v日本| 亚洲欧美国产双大乳头|