在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GTF2F1 Antibody, HRP conjugated

GTF2F1 Antibody, HRP conjugated

  • 中文名稱：
    GTF2F1兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA010004HB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GTF2F1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GTF2F1
  • 別名：
    2810405L04Rik antibody; BTF4 antibody; C76800 antibody; General transcription factor IIF 74 kDa subunit antibody; General transcription factor IIF subunit 1 antibody; General transcription factor IIF; polypeptide 1; 74kDa antibody; Gtf2f1 antibody; MGC94148 antibody; OTTHUMP00000237859 antibody; RAP74 antibody; T2FA_HUMAN antibody; TF2F1 antibody; TFIIF antibody; TFIIF-alpha antibody; Transcription initiation factor IIF subunit alpha antibody; Transcription initiation factor RAP74 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human General transcription factor IIF subunit 1 protein (1-249AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.
  • 基因功能參考文獻：
    1. An AR motif of the transactivation domain has been identified that contributes to transcriptional activity by recruiting the C-terminal domain of subunit 1 of the general transcription regulator TFIIF. PMID: 29225078
    2. These results suggest that Mediator structural shifts induced by activator binding help stably orient pol II prior to transcription initiation within the human mediator-RNA polymerase II-TFIIF assembly. PMID: 22343046
    3. Gdown1 competes with TFIIF for binding to the RPB1 and RPB5 subunits of Pol II, thereby inhibiting an essential function of TFIIF in preinitiation complex assembly. PMID: 22244332
    4. role of associated carboxyl-terminal domain phosphatase in dephosphorylating phosphoserines 2 and 5 of RNA polymerase II PMID: 12351650
    5. The alpha 1 helix of human RAP74 has an important role in the initiation and elongation of RNA chains PMID: 12354769
    6. The NMR solution structure of the C-terminal domain of RAP74 has been determined, and NMR methods have been used to map the binding sites of the C-terminus of CTD phosphatase/FCP1 on the RAP74 C-terminal fragment. PMID: 12578358
    7. cocrystal structure of the winged-helix domain of human RNA polymerase II-associating protein 74 bound to the alpha-helical C terminus of human FCP1 PMID: 12591941
    8. NMR structure of a complex containing this TFIIF subunit and the RNA polymerase II carboxyl-terminal domain phosphatase FCP1. PMID: 12732728
    9. Interaction of TFIIF subunit RAP74 with recombinant androgen receptor N-terminal activation domain AF1 leads to imposition of helical structure on the AF1 domain. PMID: 15023052
    10. TFIIF supports elongation and suppresses pausing by stabilizing the post-translocated elongation complex PMID: 15351637
    11. alpha1-Helix of RAP74 is important for supporting NTP-driven translocation by RNAP II. PMID: 15831464
    12. TFIIF and Rpb7 are involved in both early and late transcriptional stages PMID: 17848138
    13. Mutated hydrophobic residues in RAP74 C-terminal structure disrupt secondary structure elements, showing that binding of the androgen receptor N-terminal domain depends upon helix 3 in the winged-helix domain of the RAP74 C-terminal domain polypeptide. PMID: 18284209
    14. NMR and thermodynamic studies further elucidate the complex molecular mechanism by which TFIIF and FCP1 cooperate for RNAPII recycling. PMID: 19215094

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    TFIIF alpha subunit family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4652

    OMIM: 189968

    KEGG: hsa:2962

    STRING: 9606.ENSP00000377969

    UniGene: Hs.68257



主站蜘蛛池模板： 女邻居的大乳中文字幕| 久久久久波多野结衣高潮| 免费国精产品—品二品| 国产精品白浆在线观看免费 | 欧美性群另类交| 丰满少妇高潮惨叫久久久| 黑人巨大精品欧美黑寡妇| 亚洲精品久久国产高清情趣图文| 日本亚洲欧美高清专区vr专区| 在线播放国产麻豆va剧情| 伊人久久综合无码成人网| 国产午夜亚洲精品午夜鲁丝片| av无码久久久久久不卡网站| 天天综合色天天综合色h| 99久久伊人精品综合观看 | 国产精品久久久久久久久久久久| 日韩在线永久免费播放| 国产欧美一区二区精品仙草咪| 萝卜视频高清免费视频日本| 国产亚洲精品久久久久婷婷瑜伽 | 午夜免费无码福利视频| 天堂资源中文| 99久久婷婷国产综合精品电影 | 午夜成人无码福利免费视频| 国产亚洲日韩欧美另类第八页| 中文字幕卡二和卡三的视频| 国产亚洲日韩av在线播放不卡| 2022国产成人精品视频人| 精品久久久久久久久久久国产字幕| 国产精品免费观看调教网| 亚洲国产欧美在线人成最新| 亚洲综合国产成人丁香五月激情 | 亚洲国产天堂久久久久久| 亚洲成成熟女人专区| 成人天堂资源www在线| 久久精品国产99国产精2020丨| 国产在不卡免费一区二区三| 亚洲一区二区三区含羞草| 国产精品国产三级在线专区| 亚洲国产成人无码av在线影院 | 老司机在线精品视频网站|