在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GSDMC Antibody, HRP conjugated

  • 中文名稱:
    GSDMC兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA883633LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GSDMC Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GSDMC
  • 別名:
    Gasdermin C antibody; Gasdermin-C antibody; GSDMC antibody; GSDMC_HUMAN antibody; Melanoma derived leucine zipper, extra nuclear factor antibody; Melanoma-derived leucine zipper-containing extranuclear factor antibody; MLZE antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Gasdermin-C protein (1-508AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-C, N-terminal) binds to membranes and forms pores, triggering cell death.; Pore-forming protein that causes membrane permeabilization and pyroptosis. Released upon cleavage and binds to membrane inner leaflet lipids. Homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, triggering pyroptosis. The functional mechanisms and physiological proteases that cleave and activate this pore-forming protein are unknown (Probable).
  • 基因功能參考文獻:
    1. Expression of GSDMC is increased by UV irradiation in human skin keratinocytes. GSDMC induction contributes to the increase of MMP-1 expression specifically via activation of ERK and JNK pathways. PMID: 29428815
    2. Gasdermin C is upregulated by inactivation of Tgfbr2 in the presence of mutated Apc, promoting colorectal cancer cell proliferation. PMID: 27835699
    3. Study investigated the expression pattern of the GSDM family genes in the upper gastrointestinal epithelium and cancers. PMID: 19051310
  • 亞細胞定位:
    [Gasdermin-C]: Cytoplasm, cytosol.; [Gasdermin-C, N-terminal]: Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Gasdermin family
  • 組織特異性:
    Expressed mainly in trachea and spleen. In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium.
  • 數據庫鏈接:

    HGNC: 7151

    OMIM: 608384

    KEGG: hsa:56169

    UniGene: Hs.133244



主站蜘蛛池模板: 久久精品成人免费观看三| 国产a在亚洲线播放| 日韩视频在线观看| 亚洲精品日本一区二区三区| 伊人久久大香线蕉av仙人| 亚洲の无码国产の无码步美| 国产韩国精品一区二区三区久久| 女人被狂躁c到高潮视频 | 国产精品综合一区二区三区| 国产偷窥盗摄一区二区| 日本又黄又爽gif动态图| 色噜噜av亚洲色一区二区| 国产精品久久久久久亚洲影视| 国内精品乱码卡一卡2卡三卡新区| 男女爽爽无遮挡午夜视频| av老司机亚洲精品天堂| 久久精品国产久精国产一老狼| 亚洲色偷偷偷网站色偷一区| 一区二区传媒有限公司| 色五月激情五月| 少妇高潮喷潮久久久影院| 18禁亚洲深夜福利人口| 亚洲国产精品自在拍在线播放蜜臀| 国产99久久久欧美黑人刘玥| 亚欧洲乱码视频一二三区| 中文天堂在线www最新版官网| 欧美孕妇xxxx做受欧美88| 99国产精品欧美一区二区三区| 天天综合网网欲色| 亚洲国产精品日韩av不卡在线 | 无码中文字幕日韩专区视频 | 一卡二卡3卡四卡网站精品| 大陆熟妇丰满多毛xxxx| 在线亚洲视频网站www色| 最新精品国偷自产在线老年人| 国内精品久久久久久tv| 伊人色综合久久天天小片| 午夜内射中出视频| 欧美又粗又大aaa片| 国产精品国产三级在线专区| 国产成人精品久久久久精品日日|