在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GSDMC Antibody, Biotin conjugated

  • 中文名稱:
    GSDMC兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA883633LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GSDMC Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GSDMC
  • 別名:
    Gasdermin C antibody; Gasdermin-C antibody; GSDMC antibody; GSDMC_HUMAN antibody; Melanoma derived leucine zipper, extra nuclear factor antibody; Melanoma-derived leucine zipper-containing extranuclear factor antibody; MLZE antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Gasdermin-C protein (1-508AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-C, N-terminal) binds to membranes and forms pores, triggering cell death.; Pore-forming protein that causes membrane permeabilization and pyroptosis. Released upon cleavage and binds to membrane inner leaflet lipids. Homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, triggering pyroptosis. The functional mechanisms and physiological proteases that cleave and activate this pore-forming protein are unknown (Probable).
  • 基因功能參考文獻:
    1. Expression of GSDMC is increased by UV irradiation in human skin keratinocytes. GSDMC induction contributes to the increase of MMP-1 expression specifically via activation of ERK and JNK pathways. PMID: 29428815
    2. Gasdermin C is upregulated by inactivation of Tgfbr2 in the presence of mutated Apc, promoting colorectal cancer cell proliferation. PMID: 27835699
    3. Study investigated the expression pattern of the GSDM family genes in the upper gastrointestinal epithelium and cancers. PMID: 19051310
  • 亞細胞定位:
    [Gasdermin-C]: Cytoplasm, cytosol.; [Gasdermin-C, N-terminal]: Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Gasdermin family
  • 組織特異性:
    Expressed mainly in trachea and spleen. In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium.
  • 數據庫鏈接:

    HGNC: 7151

    OMIM: 608384

    KEGG: hsa:56169

    UniGene: Hs.133244



主站蜘蛛池模板: 国产又黄又爽胸又大免费视频| 久久国产乱子伦免费精品| 玩弄丰满少妇xxxxx性多毛| 综合亚洲另类欧美久久成人精品| 欧美成人精品三级网站| 亚洲欧美日韩中文久久| 亚洲精品美女久久久久99| 狠狠色综合久久丁香婷婷| 国产成人精品久久一区二区三区 | 女人与拘做受全过程免费视频| 日本肉体xxxx裸交| 日产日韩亚洲欧美综合下载| 超caopor在线公开视频| 69国产成人精品午夜福中文| 国产三级精品三级在线观看| 久久久久99精品成人片直播| 人人鲁人人莫人人爱精品| 蜜桃网站入口可看18禁| 国产成人亚洲精品无码青青草原| 亚洲午夜福利在线视频| 同性男男黄g片免费网站| 天天色影网| 狠狠色噜噜狠狠狠狠888奇禾| 国产精品乱子伦xxxx| 野外少妇激情aa 级视频| 亚洲小说春色综合另类| 丰满人妻一区二区三区视频53| 国产午夜三级一区二区三| 国产人妻大战黑人第1集| 国产成+人+综合+亚洲欧美| 久久久日韩精品一区二区三区| 爆乳女仆高潮在线观看| 狠狠做深爱婷婷久久综合一区| 国产午夜成人无码免费| 色吊丝中文字幕| 免费无码又爽又刺激高潮视频| 亚洲欧美日韩综合久久| 夜色爽爽影院18禁妓女影院| 国产婷婷色综合av蜜臀av| 快好爽射给我视频| 国产无限次数成版人视频在线|