在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GSDMC Antibody, Biotin conjugated

  • 中文名稱:
    GSDMC兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA883633LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GSDMC Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GSDMC
  • 別名:
    Gasdermin C antibody; Gasdermin-C antibody; GSDMC antibody; GSDMC_HUMAN antibody; Melanoma derived leucine zipper, extra nuclear factor antibody; Melanoma-derived leucine zipper-containing extranuclear factor antibody; MLZE antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Gasdermin-C protein (1-508AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-C, N-terminal) binds to membranes and forms pores, triggering cell death.; Pore-forming protein that causes membrane permeabilization and pyroptosis. Released upon cleavage and binds to membrane inner leaflet lipids. Homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, triggering pyroptosis. The functional mechanisms and physiological proteases that cleave and activate this pore-forming protein are unknown (Probable).
  • 基因功能參考文獻:
    1. Expression of GSDMC is increased by UV irradiation in human skin keratinocytes. GSDMC induction contributes to the increase of MMP-1 expression specifically via activation of ERK and JNK pathways. PMID: 29428815
    2. Gasdermin C is upregulated by inactivation of Tgfbr2 in the presence of mutated Apc, promoting colorectal cancer cell proliferation. PMID: 27835699
    3. Study investigated the expression pattern of the GSDM family genes in the upper gastrointestinal epithelium and cancers. PMID: 19051310
  • 亞細胞定位:
    [Gasdermin-C]: Cytoplasm, cytosol.; [Gasdermin-C, N-terminal]: Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Gasdermin family
  • 組織特異性:
    Expressed mainly in trachea and spleen. In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium.
  • 數據庫鏈接:

    HGNC: 7151

    OMIM: 608384

    KEGG: hsa:56169

    UniGene: Hs.133244



主站蜘蛛池模板: 国产精品白浆一区二小说| 四虎影视在线永久免费观看 | 色综合久久中文综合网| 一本丁香综合久久久久不卡网站| 国内午夜国产精品小视频| 欧美另类bbbxxxxx另类| 日本亚洲色大成网站www久久| 日韩av高清在线观看| 亚洲大成色www永久网站动图| 亚洲欧美中文字幕高清在线| 东京热无码av男人的天堂| 人妻无码一区二区三区 tv| 国产粉嫩小泬在线观看泬| 伊人av超碰伊人久久久| 国产suv精品一区二区62| 波多野结衣av一区二区全免费观看| 国产精品色拉拉| 中文字幕亚洲综合久久蜜桃| 午夜阳光精品一区二区三区| 狼色精品人妻在线视频免费| 国产成 人 综合 亚洲| 国产肉体xxxx裸体784大胆| 女人爽到高潮免费视频大全| 欧美成人h亚洲综合在线观看| 久九九久视频精品免费| 久久精品aⅴ无码中文字字幕蜜桃 午夜成人鲁丝片午夜精品 | 成人免费一区二区三区| 免费刺激性视频大片区| 亚洲精品第一国产综合国服瑶 | 超级大爆乳奶牛被调教出奶水| 激情欧美成人久久综合| 人妻 丝袜美腿 中文字幕| 精品国产一区二区三区久久狼| 国产成人综合日韩精品无码不卡| 国色天香中文字幕在线视频| 久久精品农村毛片| 久久理论片午夜琪琪电影网| 少妇人妻真实偷人精品视频| 都市激情 在线 亚洲 国产| 在线观看高清黄网站观看| 疯狂三人交性欧美|