在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GPR37 Antibody

GPR37 Antibody

  • 中文名稱：
    GPR37兔多克隆抗體
  • 貨號：
    CSB-PA009810OA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA009810OA01HU diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) GPR37 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    GPR37; Prosaposin receptor GPR37; Endothelin B receptor-like protein 1; ETBR-LP-1; G-protein coupled receptor 37; Parkin-associated endothelin receptor-like receptor; PAELR
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Peptide sequence from Human Prosaposin receptor GPR37 protein (114-133AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，GPR37 Antibody (CSB-PA009810OA01HU)，的標記方式是Non-conjugated。對于GPR37 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA009810OB01HU GPR37 Antibody, HRP conjugated ELISA
    FITC CSB-PA009810OC01HU GPR37 Antibody, FITC conjugated
    Biotin CSB-PA009810OD01HU GPR37 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade.
  • 基因功能參考文獻：
    1. REG4 promotes peritoneal metastasis of gastric cancer through GPR37 and triggers a positive feedback loop. PMID: 27036049
    2. GPR37 was shown to be a component of the CASPR2-MUPP1 complex in brain. PMID: 25977097
    3. GPR37 may play an important role in the pathogenesis of hepatocellular carcinoma by affecting the proliferation of HCC cells. PMID: 25169131
    4. Positive role of GPR37 in the proliferation of multiple myeloma cells. PMID: 24290813
    5. GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin. PMID: 23690594
    6. results suggested that some alleles in GPR37 were related to the deleterious effect of ASD. GPR37 is associated with the dopamine transporter to modulate dopamine uptake, and regulates behavioral responses to dopaminergic drugs PMID: 23251443
    7. results show that panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity PMID: 12670421
    8. Glup/PACRG suppresses cell death induced by accumulation of unfolded Pael receptor and facilitates the formation of Pael-R inclusions. PMID: 14532270
    9. These results suggest that 4-PBA suppresses ER stress by directly reducing the amount of misfolded protein, including Pael-R accumulated in the ER. PMID: 16539653
    10. Parkin-ko/Pael-R-tg mice represents an AR-JP mouse model displaying chronic and selective loss of catecholaminergic neurons. PMID: 18691389
    11. Data show that GPR37 overexpression can induce cellular autophagy, which may prevent the selective degeneration of GPR37-expressing neurons, as reported for Parkinson's and related neurodegenerative diseases. PMID: 19218498
    12. GPR37 surface trafficking in heterologous cells can be greatly enhanced by N-terminal truncation, coexpression with other receptors, and coexpression with syntenin-1. PMID: 19799451

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may
  • 數據庫鏈接：

    HGNC: 4494

    OMIM: 602583

    KEGG: hsa:2861

    STRING: 9606.ENSP00000306449

    UniGene: Hs.406094



主站蜘蛛池模板： 日产乱码一二三区别免费麻豆 | 久久久亚洲精华液精华液精华液| 久久超碰色中文字幕超清| 2021少妇久久久久久久久久| 天堂а√在线地址8| 日韩经典午夜福利发布| 乱码人妻一区二区三区| 欲香欲色天天天综合和网| 老湿机国产福利视频| 久久国产免费福利永久| 久久麻豆成人精品av| 色一情一乱一伦| 天天狠天天透天干天干| 亚洲国产精品无码专区成人| 伊人久久大香线蕉综合75| 国产精品久久毛片av大全日韩| 国产亚洲精品久久yy5099| 日本乱码一区二区三区不卡| a在线视频v视频| 99国产精品白浆在线观看免费| 日韩精品无码一区二区忘忧草| 国产做a爰片久久毛片a片美国 | 国产午国产午夜精华 免费| 失禁潮痉挛潮喷av在线无码| 国产草莓视频无码a在线观看 | 日本乱人伦在线观看| 成人午夜无码专区性视频性视频| 在线精品亚洲一区二区小说| 无码成人精品区在线观看| 欧美亚洲精品中文字幕乱码| 成熟女人特级毛片www免费| 露脸内射熟女--69xx| 一区二区三区视频| 亚洲国产v高清在线观看| 亚洲欧洲美洲在线观看| 大陆熟妇丰满多毛xxxx| 国产激情大臿免费视频| 婷婷伊人久久大香线蕉av| 小说区 图片区色 综合区| 国产亚洲欧美另类一区二区| 国产精品成人观看视频国产奇米|