在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GPR37 Antibody

  • 中文名稱:
    GPR37兔多克隆抗體
  • 貨號:
    CSB-PA009810GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    GPR37; Prosaposin receptor GPR37; Endothelin B receptor-like protein 1; ETBR-LP-1; G-protein coupled receptor 37; Parkin-associated endothelin receptor-like receptor; PAELR
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human GPR37
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade.
  • 基因功能參考文獻:
    1. REG4 promotes peritoneal metastasis of gastric cancer through GPR37 and triggers a positive feedback loop. PMID: 27036049
    2. GPR37 was shown to be a component of the CASPR2-MUPP1 complex in brain. PMID: 25977097
    3. GPR37 may play an important role in the pathogenesis of hepatocellular carcinoma by affecting the proliferation of HCC cells. PMID: 25169131
    4. Positive role of GPR37 in the proliferation of multiple myeloma cells. PMID: 24290813
    5. GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin. PMID: 23690594
    6. results suggested that some alleles in GPR37 were related to the deleterious effect of ASD. GPR37 is associated with the dopamine transporter to modulate dopamine uptake, and regulates behavioral responses to dopaminergic drugs PMID: 23251443
    7. results show that panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity PMID: 12670421
    8. Glup/PACRG suppresses cell death induced by accumulation of unfolded Pael receptor and facilitates the formation of Pael-R inclusions. PMID: 14532270
    9. These results suggest that 4-PBA suppresses ER stress by directly reducing the amount of misfolded protein, including Pael-R accumulated in the ER. PMID: 16539653
    10. Parkin-ko/Pael-R-tg mice represents an AR-JP mouse model displaying chronic and selective loss of catecholaminergic neurons. PMID: 18691389
    11. Data show that GPR37 overexpression can induce cellular autophagy, which may prevent the selective degeneration of GPR37-expressing neurons, as reported for Parkinson's and related neurodegenerative diseases. PMID: 19218498
    12. GPR37 surface trafficking in heterologous cells can be greatly enhanced by N-terminal truncation, coexpression with other receptors, and coexpression with syntenin-1. PMID: 19799451

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may
  • 數據庫鏈接:

    HGNC: 4494

    OMIM: 602583

    KEGG: hsa:2861

    STRING: 9606.ENSP00000306449

    UniGene: Hs.406094



主站蜘蛛池模板: 成 人 色 网 站免费观看| 国产日韩综合一区在线观看| 天天躁夜夜躁狠狠综合 | 四虎成人精品在永久免费| 国产中老年妇女精品| 人妻换人妻仑乱| 国模无码人体一区二区| 久久三级中文欧大战字幕| 成人亚洲欧美激情在线电影| 色偷偷av亚洲男人的天堂| 4438xx亚洲最大五色丁香| 久久婷婷五月综合色首页| 国内精品一区二区三区不卡| 少妇仑乱a毛片| 中文字幕人成乱码熟女免费 | 久久久久久久波多野结衣高潮| 色天使久久综合给合久久97色 | 国产精品麻豆aⅴ人妻| 伊人久久精品无码av一区| 中国少妇内射xxxx狠干| 丰满诱人的人妻3| 色欲视频综合免费天天| 国产成人av综合久久视色| 午夜精品一区二区三区在线视| 日韩va中文字幕无码电影| 最新69国产成人精品视频免费| 欧美日激情日韩精品嗯| 中文字幕日产乱码国内自| 人妻熟女一区二区aⅴ千叶宁真| 美女黄18以下禁止观看| 东京热一精品无码av| 牲交a欧美牲交aⅴ免费一| 啦啦啦www在线观看免费视频 | 天天澡天天揉揉av在线| 精品国产免费观看久久久| 日本一卡二卡3卡四卡网站精品| 国精产品999国精产品官网| 亚洲国产成人精品久久久| 亚洲欧美日韩综合一区在线| 无码av免费网站| 欧美性生交大片免费看|