在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GPR37 Antibody, Biotin conjugated

  • 中文名稱:
    GPR37兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA009810ND01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GPR37 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    GPR37; Prosaposin receptor GPR37; Endothelin B receptor-like protein 1; ETBR-LP-1; G-protein coupled receptor 37; Parkin-associated endothelin receptor-like receptor; PAELR
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Peptide sequence from Human Prosaposin receptor GPR37 protein (114-133AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor for the neuroprotective and glioprotective factor prosaposin. Ligand binding induces endocytosis, followed by an ERK phosphorylation cascade.
  • 基因功能參考文獻:
    1. REG4 promotes peritoneal metastasis of gastric cancer through GPR37 and triggers a positive feedback loop. PMID: 27036049
    2. GPR37 was shown to be a component of the CASPR2-MUPP1 complex in brain. PMID: 25977097
    3. GPR37 may play an important role in the pathogenesis of hepatocellular carcinoma by affecting the proliferation of HCC cells. PMID: 25169131
    4. Positive role of GPR37 in the proliferation of multiple myeloma cells. PMID: 24290813
    5. GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin. PMID: 23690594
    6. results suggested that some alleles in GPR37 were related to the deleterious effect of ASD. GPR37 is associated with the dopamine transporter to modulate dopamine uptake, and regulates behavioral responses to dopaminergic drugs PMID: 23251443
    7. results show that panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity PMID: 12670421
    8. Glup/PACRG suppresses cell death induced by accumulation of unfolded Pael receptor and facilitates the formation of Pael-R inclusions. PMID: 14532270
    9. These results suggest that 4-PBA suppresses ER stress by directly reducing the amount of misfolded protein, including Pael-R accumulated in the ER. PMID: 16539653
    10. Parkin-ko/Pael-R-tg mice represents an AR-JP mouse model displaying chronic and selective loss of catecholaminergic neurons. PMID: 18691389
    11. Data show that GPR37 overexpression can induce cellular autophagy, which may prevent the selective degeneration of GPR37-expressing neurons, as reported for Parkinson's and related neurodegenerative diseases. PMID: 19218498
    12. GPR37 surface trafficking in heterologous cells can be greatly enhanced by N-terminal truncation, coexpression with other receptors, and coexpression with syntenin-1. PMID: 19799451

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may
  • 數據庫鏈接:

    HGNC: 4494

    OMIM: 602583

    KEGG: hsa:2861

    STRING: 9606.ENSP00000306449

    UniGene: Hs.406094



主站蜘蛛池模板: 野花社区免费观看在线www| 18禁勿入午夜网站入口| 2020最新无码国产在线观看| 久九九久视频精品免费| 无码人妻aⅴ一区二区三区69岛 | 亚洲熟妇无码一区二区三区| 亚洲精品成人片在线观看精品字幕 | 国产1卡2卡3卡4卡免费| 成 人 社区在线视频| 真人与拘做受免费视频一| 国产精品精华液网站| 日本熟妇大乳| 亚洲欧洲日产国码中文字幕| 国产成人精品a∨一区二区| 国产97色在线 | 欧洲| 久久人妻av一区二区软件 | 久久视频这里只精品| 50岁熟妇的呻吟声对白| 在线成人www免费观看视频| 国产成人免费ā片在线观看| 在教室伦流澡到高潮hgl动漫| 久久亚洲色www成人不卡| 夜夜躁很很躁日日躁麻豆| 日韩免费无码一区二区视频| 狼友av永久网站免费观看孕交 | 青青草国产精品欧美成人| 人人狠狠综合久久亚洲爱咲| 欧美三根一起进三p| 亚洲精品av中文字幕在线| 亚洲精品无码成人片| 国产日韩一区二区三区在线观看| 欧美肉大捧一进一出免费视频| 久久精品国产99国产精品导航 | 无遮挡国产高潮视频免费观看| 亚洲精品国产精品国产自2022| 日本xxxx少妇高清hd| 亚洲欧美乱日韩乱国产| 久久成人国产精品免费| 2018年秋霞无码片 | 成 年 人 黄 色 大 片大 全| 国产亚洲日本精品成人专区|