在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GNRH2 Antibody, HRP conjugated

  • 中文名稱:
    GNRH2兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA009636LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GNRH2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GNRH2
  • 別名:
    GnRH II antibody; GnRH-associated peptide 2 antibody; GnRH-associated peptide II antibody; gnrh2 antibody; GON2_HUMAN antibody; Gonadoliberin II antibody; Gonadotropin-releasing hormone 2 antibody; Gonadotropin-releasing hormone II antibody; LH-RH II antibody; Luliberin II antibody; Luteinizing hormone-releasing hormone II antibody; Progonadoliberin 2 antibody; Progonadoliberin II antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Progonadoliberin-2 protein (24-120AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.
  • 基因功能參考文獻:
    1. GnRHII expression correlated significantly with poor prognosis in breast cancer patients. PMID: 23287110
    2. results suggest GnRH-II-induced laminin receptor precursor expression increases 67-kDa nonintegrin laminin receptor, which appears to interact with laminin in the extracellular matrix to promote MMP-2 expression and enhance ovarian cancer cell invasion PMID: 21193558
    3. concluded that GnRHII stimulates PI3K/Akt pathway, and the phosphorylation of glycogen synthase kinase3beta, thereby enhancing the beta-catenin-dependent up-regulation of MT1-MMP production which contributes to ovarian cancer metastasis PMID: 21239435
    4. These preliminary data suggest that local GnRH-II may participate in the regulation of ovarian tumor growth in post-menopausal women. PMID: 20018426
    5. a novel mechanism in stimulating basal human GnRH-II gene transcription mediated by cooperative actions of multiple regulatory elements within the untranslated first exon of the gene. PMID: 12663744
    6. GnRH-II has been identified, together with a 'putative' type II GnRH receptor, both in the central nervous system and in peripheral structures, such as tissues of the reproductive tract (both normal and tumoral). PMID: 14726258
    7. GnRH-II did not affect proliferation of normal B-cells alone, and did not alter the proliferative response to IL-2. PMID: 15578334
    8. Expression of GnRH2 protein and receptor (GnRHR2) is confirmed in both leiomyoma and patient-matched myometrium. PMID: 17296196
    9. these data demonstrate the differential roles of NF-kappaB p65 and RARalpha/RXRalpha, interacting with the same sequence in the promoter of the human GnRH II gene to influence gene expression in a cell-specific manner. PMID: 17451432
    10. GnRH II is widely expressed in prostate cancer and is an AR-regulated gene. PMID: 17914092
    11. p-CREB, C/EBPbeta, and CBP are recruited to the CRE of the GnRH-II promoter in a temporarily defined manner to enhance its transcription in JEG-3 and OVCAR-3 cells in response to cAMP PMID: 18599546
    12. These results provide evidence that EGF is an upstream regulator of the autocrine actions of GnRH-II on the invasive properties of ovarian cancer cells. PMID: 19608641

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    GnRH family
  • 組織特異性:
    Midbrain; expressed at significantly higher levels outside the brain (up to 30-fold), particularly in the kidney, bone marrow and prostate.
  • 數據庫鏈接:

    HGNC: 4420

    OMIM: 602352

    KEGG: hsa:2797

    STRING: 9606.ENSP00000245983

    UniGene: Hs.129715



主站蜘蛛池模板: 国产三级在线观看免费| 人妻夜夜爽天天爽三区丁香花| 无码一区二区三区免费| 亚洲日韩性欧美中文字幕| 性色av一区二区三区人妻| 人妻熟女一区二区aⅴ水野朝阳| 亚洲午夜无码久久久久软件| 中文字幕人成乱码熟女| 人妻激情偷乱一区二区三区| 国产精品色拉拉| 精品国产午夜理论片不卡精品| 国产国拍亚洲精品av在线| 免费国产a国产片高清| 亚洲欧洲日产最新| 色视频综合无码一区二区三区| 精品蜜臀久久久久99网站| 国产av无码专区国产乱码 | 亚洲va久久久噜噜噜久久4399| 免费无人区男男码卡二卡| 97精品尹人久久大香线蕉| 亚洲愉拍自拍欧美精品| 久久99精品久久久久久噜噜| 日本妇人成熟免费中文字幕| 人妻三级日本香港三级极97| 无套内射极品少妇chinese| 成年女人午夜毛片免费视频| 变态另类牲交乱| 欧美人与性动交g欧美精器| 亚洲成a人片在线观看中文| 国产在热线精品视频99公交| 国产好大好硬好爽免费视频| 国产老熟女伦老熟妇露脸| 精品国产一区二区三区色欲| 天天躁日日躁狠狠躁人妻| 亚洲国产成人精品无码区在线| 熟妇好大好深好满好爽| 国产精品被窝福利一区 | 免费天堂无码人妻成人av电影| 色爽黄1000部免费软件下载| 无码尹人久久相蕉无码| 国内精品久久久久影院优|