在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GNRH2 Antibody, FITC conjugated

GNRH2 Antibody, FITC conjugated

  • 中文名稱：
    GNRH2兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA009636LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GNRH2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GNRH2
  • 別名：
    GnRH II antibody; GnRH-associated peptide 2 antibody; GnRH-associated peptide II antibody; gnrh2 antibody; GON2_HUMAN antibody; Gonadoliberin II antibody; Gonadotropin-releasing hormone 2 antibody; Gonadotropin-releasing hormone II antibody; LH-RH II antibody; Luliberin II antibody; Luteinizing hormone-releasing hormone II antibody; Progonadoliberin 2 antibody; Progonadoliberin II antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Progonadoliberin-2 protein (24-120AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.
  • 基因功能參考文獻(xiàn)：
    1. GnRHII expression correlated significantly with poor prognosis in breast cancer patients. PMID: 23287110
    2. results suggest GnRH-II-induced laminin receptor precursor expression increases 67-kDa nonintegrin laminin receptor, which appears to interact with laminin in the extracellular matrix to promote MMP-2 expression and enhance ovarian cancer cell invasion PMID: 21193558
    3. concluded that GnRHII stimulates PI3K/Akt pathway, and the phosphorylation of glycogen synthase kinase3beta, thereby enhancing the beta-catenin-dependent up-regulation of MT1-MMP production which contributes to ovarian cancer metastasis PMID: 21239435
    4. These preliminary data suggest that local GnRH-II may participate in the regulation of ovarian tumor growth in post-menopausal women. PMID: 20018426
    5. a novel mechanism in stimulating basal human GnRH-II gene transcription mediated by cooperative actions of multiple regulatory elements within the untranslated first exon of the gene. PMID: 12663744
    6. GnRH-II has been identified, together with a 'putative' type II GnRH receptor, both in the central nervous system and in peripheral structures, such as tissues of the reproductive tract (both normal and tumoral). PMID: 14726258
    7. GnRH-II did not affect proliferation of normal B-cells alone, and did not alter the proliferative response to IL-2. PMID: 15578334
    8. Expression of GnRH2 protein and receptor (GnRHR2) is confirmed in both leiomyoma and patient-matched myometrium. PMID: 17296196
    9. these data demonstrate the differential roles of NF-kappaB p65 and RARalpha/RXRalpha, interacting with the same sequence in the promoter of the human GnRH II gene to influence gene expression in a cell-specific manner. PMID: 17451432
    10. GnRH II is widely expressed in prostate cancer and is an AR-regulated gene. PMID: 17914092
    11. p-CREB, C/EBPbeta, and CBP are recruited to the CRE of the GnRH-II promoter in a temporarily defined manner to enhance its transcription in JEG-3 and OVCAR-3 cells in response to cAMP PMID: 18599546
    12. These results provide evidence that EGF is an upstream regulator of the autocrine actions of GnRH-II on the invasive properties of ovarian cancer cells. PMID: 19608641

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    GnRH family
  • 組織特異性：
    Midbrain; expressed at significantly higher levels outside the brain (up to 30-fold), particularly in the kidney, bone marrow and prostate.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4420

    OMIM: 602352

    KEGG: hsa:2797

    STRING: 9606.ENSP00000245983

    UniGene: Hs.129715



主站蜘蛛池模板： 性高湖久久久久久久久| 精品国产制服丝袜高跟| 69天堂人成无码免费视频| 国产精品人妻一区夜夜爱| 亚洲国产综合在线区尤物| 看国产一毛片在线看手机看 | 天天综合爱天天综合色| 国产区在线观看成人精品| 137日本免费肉体摄影| 亚洲精品一区二区玖玖爱| 久久人妻内射无码一区三区| 日本少妇被黑人猛cao| 太深太粗太爽太猛了视频免费观看 | 骚女人干起来舒服视频在线| 一本无码人妻在中文字幕免费| 内射少妇一区27p| 亚洲自偷自拍另类小说| 午夜福利不卡在线视频| 国产九九99久久99大香伊| 国产人成无码视频在线| 日本丰满熟妇bbxbbxhd| 69精品人人人人| 亚洲最新无码中文字幕久久| 欧美成人国产精品高潮| www婷婷av久久久影片| 国内乱码一线二线三线| 欲香欲色天天综合久久| 亚洲色老汉av无码专区最 | 日本两人免费观看的视频| 中文字幕乱码人在线视频1区| 日本熟妇大乳| 欧美xxxx精品另类| 久久婷婷五月综合色99啪| 真人与拘做受免费视频| 久久久噜噜噜久久| 中国6一12呦女精品| 丰满人妻熟妇乱又仑精品| 欧美日韩精品一区二区在线视频| 2018av无码视频在线播放| 国产国产裸模裸模私拍视频| 隔壁人妻被水电工征服|