在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GJB4 Antibody

  • 中文名稱:
    GJB4兔多克隆抗體
  • 貨號:
    CSB-PA293314
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA293314(GJB4 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA293314(GJB4 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse skin tissue, Primary antibody: CSB-PA293314(GJB4 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    GJB4
  • 別名:
    GJB4; Gap junction beta-4 protein; Connexin-30.3; Cx30.3
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthetic peptide of Human GJB4
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.
  • 基因功能參考文獻:
    1. GJB4 may be a genetic risk factor for the development of nonsyndromic hearing loss and the data from the present study can be used to direct the clinical evaluation and effectively manage the care of families of children with GJB4. PMID: 25333454
    2. In this study, we found no mutations of GJB4 in two Progressive symmetrical erythrokeratoderma families. PMID: 23678955
    3. Letter: describe erythrokeratodermia variabilis phenotype related to novel mutation in GJB4 gene. PMID: 23037955
    4. Mutation analysis of GJB3 and GJB4 in Chinese patients with erythrokeratodermia variabilis. PMID: 21950330
    5. Bidirectional sequencing of the coding region of GJB4 revealed a novel c.295G>A missense mutation. PMID: 22266302
    6. There were no mutations found in the GJB4 gene and the true pathogenesis of progressive symmetrical erythrokeratodermia remains unknown. PMID: 21198793
    7. A common frameshift mutation and other variants in GJB4 (connexin 30.3): Analysis of hearing impairment families PMID: 11933201
    8. the involvement of connexin gene 30.3 (GJB4) in the etiology of erythrokeratodermia variabilis PMID: 12648223
    9. These results not only provide new insights into epidermal connexin synthesis and polymerization, but also allow a novel molecular explanation for the similarity of EKV phenotypes. PMID: 14583444
    10. Not all clinically diagnosed individuals with erythrokeratoderma variabilis harbor Cx30.3 disease-associated mutations. PMID: 16297190
    11. Five patients with erythrokeratodermia variabilis of Mendes da Costa and progressive symmetric erythrokeratodermia of Gottron had the same mutation in the GJB4 gene causing the amino acid substitution p.Gly12Asp (G12D). PMID: 19291775

    顯示更多

    收起更多

  • 相關疾病:
    Erythrokeratodermia variabilis et progressiva 2 (EKVP2)
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
  • 蛋白家族:
    Connexin family, Beta-type (group I) subfamily
  • 數據庫鏈接:

    HGNC: 4286

    OMIM: 605425

    KEGG: hsa:127534

    STRING: 9606.ENSP00000345868

    UniGene: Hs.351203



主站蜘蛛池模板: 亚洲精品嫩草研究院久久| 免费播放一区二区三区| 欧美成人综合久久精品| 久久九九有精品国产23百花影院 | 精品人妻系列无码人妻漫画| 中文字幕无线码一区2020青青| 亚洲爆乳无码专区www| 综合久久—本道中文字幕| 亚洲欧美日韩国产精品一区| 日本无遮挡边做边爱边摸| 天码av无码一区二区三区四区| 亚洲中文色欧另类欧美| 国产高清在线精品一区小说| 欧美xxxx黑人又粗又长| 国产精品无码专区| 亚洲色成人www永久网站| 欧美国产日韩a在线观看| 99久视频只有精品2019| 日本高清视频wwww色| 亚洲国产精品久久久久秋霞影院| 久久国内精品自在自线| 国产亚洲欧美日韩精品一区二区| 国产乱子伦60女人的皮视频| 青青草97国产精品免费观看| 国产真实交换配乱婬95视频| 动漫精品专区一区二区三区| 婷婷射精av这里只有精品| 国产美女精品一区二区三区| 国产99视频精品免费专区| 欧美激性欧美激情在线| 欧美性猛交xxxx乱大交| 奇米影视888欧美在线观看 | 亚洲精品中国国产嫩草影院美女 | 国产草莓精品国产av片国产| 久久国产免费福利永久| 无码播放一区二区三区| 人妻久久久一区二区三区| 国产精品性夜天天拍拍2021| 亚洲成aⅴ人最新无码| 国产又色又爽又黄的免费| 亚洲中文字幕无码一区在线|