在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GJB4 Antibody

GJB4 Antibody

  • 中文名稱：
    GJB4兔多克隆抗體
  • 貨號(hào)：
    CSB-PA558294
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA558294(GJB4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA558294(GJB4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse skin tissue, Hela cells, Primary antibody: CSB-PA558294(GJB4 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    GJB4
  • 別名：
    GJB4; Gap junction beta-4 protein; Connexin-30.3; Cx30.3
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human GJB4
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.
  • 基因功能參考文獻(xiàn)：
    1. GJB4 may be a genetic risk factor for the development of nonsyndromic hearing loss and the data from the present study can be used to direct the clinical evaluation and effectively manage the care of families of children with GJB4. PMID: 25333454
    2. In this study, we found no mutations of GJB4 in two Progressive symmetrical erythrokeratoderma families. PMID: 23678955
    3. Letter: describe erythrokeratodermia variabilis phenotype related to novel mutation in GJB4 gene. PMID: 23037955
    4. Mutation analysis of GJB3 and GJB4 in Chinese patients with erythrokeratodermia variabilis. PMID: 21950330
    5. Bidirectional sequencing of the coding region of GJB4 revealed a novel c.295G>A missense mutation. PMID: 22266302
    6. There were no mutations found in the GJB4 gene and the true pathogenesis of progressive symmetrical erythrokeratodermia remains unknown. PMID: 21198793
    7. A common frameshift mutation and other variants in GJB4 (connexin 30.3): Analysis of hearing impairment families PMID: 11933201
    8. the involvement of connexin gene 30.3 (GJB4) in the etiology of erythrokeratodermia variabilis PMID: 12648223
    9. These results not only provide new insights into epidermal connexin synthesis and polymerization, but also allow a novel molecular explanation for the similarity of EKV phenotypes. PMID: 14583444
    10. Not all clinically diagnosed individuals with erythrokeratoderma variabilis harbor Cx30.3 disease-associated mutations. PMID: 16297190
    11. Five patients with erythrokeratodermia variabilis of Mendes da Costa and progressive symmetric erythrokeratodermia of Gottron had the same mutation in the GJB4 gene causing the amino acid substitution p.Gly12Asp (G12D). PMID: 19291775

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Erythrokeratodermia variabilis et progressiva 2 (EKVP2)
  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
  • 蛋白家族：
    Connexin family, Beta-type (group I) subfamily
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 4286

    OMIM: 605425

    KEGG: hsa:127534

    STRING: 9606.ENSP00000345868

    UniGene: Hs.351203



主站蜘蛛池模板： 日韩精品无码一区二区中文字幕 | 日本高清在线天码一区播放| 800av凹凸视频在线观看| 一本加勒比波多野结衣| 欧美 丝袜 自拍 制服 另类| 亚洲国产欧美国产综合久久| 18禁男女无遮挡啪啪网站| 国产一区二区三区美女| 人妻aⅴ无码一区二区三区| 久久精品人人爽人人爽| 免费国产高清在线精品一区| 国产亚洲精久久久久久无码苍井空 | 亚洲综合色区中文字幕| 我的公把我弄高潮了视频| 十八禁真人啪啪免费网站 | 精品夜夜爽欧美毛片视频| 国产免费爽爽视频| 欧美大香线蕉线伊人久久| 日日天干夜夜狠狠爱| 日本强伦姧人妻一区二区| 亚洲中文字幕久久精品蜜桃| 伊人色合天天久久综合网| 疯狂撞击丝袜人妻| 中文字幕无码日韩专区| 国产做a爰片久久毛片a片美国| 国产精品一卡二卡三卡四卡| 高清无码一区二区在线观看吞精| 亚洲精品成人久久电影网| 漂亮人妻洗澡被公强 日日躁| 日本电影一区二区三区| 色综合视频一区中文字幕| 在线a久青草视频在线观看| 揄拍成人国产精品视频| 久久精品人妻无码一区二区三区v| 在线a毛片免费视频观看| 欧美拍拍视频免费大全| 又黄又爽又色的视频| 宅宅午夜无码一区二区三区| 亚洲视频一区| 国产成人a人亚洲精品无码 | 国产精品日本亚洲欧美|