在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GFRA2 Antibody

  • 中文名稱:
    GFRA2兔多克隆抗體
  • 貨號:
    CSB-PA009380LA01HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: HepG2 whole cell lysate, A549 whole cell lysate, Mouse liver tissue, Mouse lung tissue, Mouse kidney tissue, Mouse brain tissue
      All lanes: GFRA2 antibody at 3.5μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 52, 37, 40 kDa
      Observed band size: 34 kDa
    • Immunofluorescent analysis of HepG2 cells using CSB-PA009380LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GFRA2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GFRA2
  • 別名:
    GDNF family receptor alpha 2 antibody; GDNF family receptor alpha-2 antibody; GDNF receptor alpha-2 antibody; GDNF receptor beta antibody; GDNFR beta antibody; GDNFR-alpha-2 antibody; GDNFR-beta antibody; GDNFRB antibody; GFR alpha 2 antibody; GFR-alpha-2 antibody; GFRA 2 antibody; Gfra2 antibody; GFRA2_HUMAN antibody; Glial cell line derived neurotrophic factor family receptor alpha2b antibody; Glial cell line derived neurotrophic factor receptor beta antibody; Neurturin receptor alpha antibody; NRTNR alpha antibody; NRTNR-alpha antibody; NTNR alpha antibody; NTNR-alpha antibody; NTNRA antibody; PI linked cell surface accessory protein antibody; PI linked cell-surface accessory protein antibody; RET ligand 2 antibody; RETL 2 antibody; RETL2 antibody; TGF beta related neurotrophic factor receptor 2 antibody; TGF-beta-related neurotrophic factor receptor 2 antibody; TRN receptor GPI anchored antibody; TRNR 2 antibody; TRNR2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human GDNF family receptor alpha-2 protein (242-415AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,GFRA2 Antibody (CSB-PA009380LA01HU),的標記方式是Non-conjugated。對于GFRA2 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA009380LB01HU GFRA2 Antibody, HRP conjugated ELISA
    FITC CSB-PA009380LC01HU GFRA2 Antibody, FITC conjugated
    Biotin CSB-PA009380LD01HU GFRA2 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.; participates in NRTN-induced 'Ser-727' phosphorylation of STAT3.
  • 基因功能參考文獻:
    1. biophysical results show that the relative concentration of GFRa2 on cell surfaces can affect the functional affinity of NRTN through avidity effects. PMID: 29414779
    2. The cardiac GFRA2 signaling pathway is distinct from the canonical pathway dependent on the RET tyrosine kinase. PMID: 27396331
    3. High GFRalpha2 expression level leads to PTEN inactivation via Mir-17-5p up-regulation, promoting pancreatic tumor cell growth and chemoresistance. PMID: 27400681
    4. GFRA2 variants associated with diabetic neuropathic pain. PMID: 24974787
    5. GFRalpha2 is under-expressed in functioning adenomas and over-expressed in non-functioning adenomas, specifically gonadotropinomas PMID: 24402129
    6. In the cochlea, immunolabeling for GFRalpha-2 receptors was identified mainly in the cell bodies of the spiral neurons than in the nerve fibers. No structures in the organ of Corti were labeled with GFRalpha-2 receptor antibody PMID: 24139947
    7. GFRalpha-2 is associated with severe abdominal pain sensation in pancreatic cancer patients. PMID: 24067900
    8. Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRalpha2 isoforms. PMID: 21723942
    9. GFRA2 genetic variants, and age, may play a role in susceptibility to tardive dyskinesia. PMID: 20369355
    10. Both GFR alpha2a and GFR alpha2c, but not GFR alpha2b, promote neurite outgrowth in transfected Neuro2A cells. PMID: 17522305
    11. GFRalpha-2 were observed within sensory and motor nuclei of cranial nerves, dorsal column nuclei, olivary nuclear complex, reticular formation, pontine nuclei, locus caeruleus, raphe nuclei, substantia nigra, and quadrigeminal plate. PMID: 17825269

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族:
    GDNFR family
  • 組織特異性:
    Isoform 1 is found in both brain and placenta.
  • 數據庫鏈接:

    HGNC: 4244

    OMIM: 601956

    KEGG: hsa:2675

    STRING: 9606.ENSP00000428518

    UniGene: Hs.441202



主站蜘蛛池模板: 中文字幕无码精品亚洲资源网| 亚洲无线码在线一区观看| 日本熟妇大乳| 亚洲高清专区日韩精品| 最新777第四色米奇影视| 欧美人与zoxxxx另类| 大乳丰满人妻中文字幕日本| 97影院理论片手机在线观看| 亚洲一区波多野结衣在线| 成人无码av网站在线观看| 精品人妻无码区二区三区| 18禁无遮挡免费视频网站| 人人做人人妻人人精| 丰满人妻被公侵犯完整版| 浓毛欧美老妇乱子伦视频| 综合 欧美 亚洲日本| 色综合天天综合网中文| 午夜伦4480yy私人影院久久| 久久97超碰色中文字幕总站| 精品国产欧美一区二区| 久久婷婷色香五月综合缴缴情| 久久精品成人免费观看| 亚洲另类欧美综合久久图片区 | 国产精品区av| 天天躁日日躁很很很躁| 天天做天天大爽天天爱| 狠狠噜天天噜日日噜色综合| 黄瓜视频在线观看网址| 国产成人精品一区二三区在线观看| 国产精品毛片完整版视频| 国产女主播白浆在线看| 亚洲自偷自拍熟女另类| 久久先锋男人av资源网站| 2018高清日本一道国产-在| 欧美黑人又粗又大久久久| 曰本女人与公拘交酡| 狠狠久久精品中文字幕无码 | 久久久久成人精品无码中文字幕 | 日韩av无码中文无码电影| 性开放的欧美大片| 亚洲人成在线观看|