在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GFRA2 Antibody

  • 中文名稱:
    GFRA2兔多克隆抗體
  • 貨號:
    CSB-PA135383
  • 規格:
    ¥1100
  • 圖片:
    • Gel: 10%SDS-PAGE, Lysate: 60 μg, Lane: Human liver cancer tissue, Primary antibody: CSB-PA135383(GFRA2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    GFRA2
  • 別名:
    GDNF family receptor alpha 2 antibody; GDNF family receptor alpha-2 antibody; GDNF receptor alpha-2 antibody; GDNF receptor beta antibody; GDNFR beta antibody; GDNFR-alpha-2 antibody; GDNFR-beta antibody; GDNFRB antibody; GFR alpha 2 antibody; GFR-alpha-2 antibody; GFRA 2 antibody; Gfra2 antibody; GFRA2_HUMAN antibody; Glial cell line derived neurotrophic factor family receptor alpha2b antibody; Glial cell line derived neurotrophic factor receptor beta antibody; Neurturin receptor alpha antibody; NRTNR alpha antibody; NRTNR-alpha antibody; NTNR alpha antibody; NTNR-alpha antibody; NTNRA antibody; PI linked cell surface accessory protein antibody; PI linked cell-surface accessory protein antibody; RET ligand 2 antibody; RETL 2 antibody; RETL2 antibody; TGF beta related neurotrophic factor receptor 2 antibody; TGF-beta-related neurotrophic factor receptor 2 antibody; TRN receptor GPI anchored antibody; TRNR 2 antibody; TRNR2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthetic peptide of Human GFRA2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    WB 1:200-1:1000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.; participates in NRTN-induced 'Ser-727' phosphorylation of STAT3.
  • 基因功能參考文獻:
    1. biophysical results show that the relative concentration of GFRa2 on cell surfaces can affect the functional affinity of NRTN through avidity effects. PMID: 29414779
    2. The cardiac GFRA2 signaling pathway is distinct from the canonical pathway dependent on the RET tyrosine kinase. PMID: 27396331
    3. High GFRalpha2 expression level leads to PTEN inactivation via Mir-17-5p up-regulation, promoting pancreatic tumor cell growth and chemoresistance. PMID: 27400681
    4. GFRA2 variants associated with diabetic neuropathic pain. PMID: 24974787
    5. GFRalpha2 is under-expressed in functioning adenomas and over-expressed in non-functioning adenomas, specifically gonadotropinomas PMID: 24402129
    6. In the cochlea, immunolabeling for GFRalpha-2 receptors was identified mainly in the cell bodies of the spiral neurons than in the nerve fibers. No structures in the organ of Corti were labeled with GFRalpha-2 receptor antibody PMID: 24139947
    7. GFRalpha-2 is associated with severe abdominal pain sensation in pancreatic cancer patients. PMID: 24067900
    8. Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRalpha2 isoforms. PMID: 21723942
    9. GFRA2 genetic variants, and age, may play a role in susceptibility to tardive dyskinesia. PMID: 20369355
    10. Both GFR alpha2a and GFR alpha2c, but not GFR alpha2b, promote neurite outgrowth in transfected Neuro2A cells. PMID: 17522305
    11. GFRalpha-2 were observed within sensory and motor nuclei of cranial nerves, dorsal column nuclei, olivary nuclear complex, reticular formation, pontine nuclei, locus caeruleus, raphe nuclei, substantia nigra, and quadrigeminal plate. PMID: 17825269

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族:
    GDNFR family
  • 組織特異性:
    Isoform 1 is found in both brain and placenta.
  • 數據庫鏈接:

    HGNC: 4244

    OMIM: 601956

    KEGG: hsa:2675

    STRING: 9606.ENSP00000428518

    UniGene: Hs.441202



主站蜘蛛池模板: 欧美日韩免费做爰大片人| 最新无码a∨在线观看| 青青热久免费精品视频| 国产成人8x视频网站入口| 精品无码国产一区二区三区51安| 精品黑人一区二区三区| 99久久久无码国产精品动漫| 日本少妇三级hd激情在线观看| 国产无遮挡a片又黄又爽漫画| 亚洲伊人成综合网| 免费无遮挡无码永久在线观看视频| 国语对白做受xxxxx在线中国 | 免费无码毛片一区二区app| 欧美深性狂猛ⅹxxx深喉| 婷婷色爱区综合五月激情| 日韩国产成人无码av毛片蜜柚| 产精品视频在线观看免费 | 亚洲愉拍自拍另类图片| 亚洲色欲色欱www在线| 婷婷无套内射影院| 亚洲日产av中文字幕无码偷拍| 国产精品福利2020久久| 国产妇女馒头高清泬20p多| 久久精品国产亚洲7777| 国产高清av喷水白丝护士| 国产精品久久久久久成人影院| 午夜福利视频| 亚洲成a人片在线观看无码专区| 四虎影视永久免费观看| 久久综合99re88久久爱| 精品欧美аv高清免费视频| 久久久久人妻一区精品果冻| 免费看少妇作爱视频| 中文字幕一区二区人妻电影| 日日天日日夜日日摸| 精品一区二区三区在线播放视频| 艳妇臀荡乳欲伦交换h在线观看| 国精品午夜福利视频不卡| 亚洲综合网站久久久| 性xxxx欧美老妇506070| 美女高潮黄又色高清视频免费|