在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GCHFR Antibody

GCHFR Antibody

  • 中文名稱：
    GCHFR兔多克隆抗體
  • 貨號(hào)：
    CSB-PA109145
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using GCHFR antibody.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GCHFR Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GCHFR
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from internal of Human GCHFR.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:50-1:100
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine.
  • 基因功能參考文獻(xiàn)：
    1. homozygous individuals for the TT haplotype were less likely to respond to the SSRI fluoxetine than to the nortriptyline suggesting a biological process through which GCHFR promoter variants might influence antidepressant response. PMID: 20351752
    2. Bacterial lipopolysaccharide down-regulates expression of GTP cyclohydrolase I feedback regulatory protein PMID: 11799107
    3. allosteric regulation of GTPCH-I activity in the cardiovascular system maybe an important mechanism regulating BH4 levels through GTPCH-I feedback regulatory protein signaling PMID: 15649650
    4. GFRP/GTPCHI axis functions in epidermal keratinocytes and melanocytes in the cytosol and nucleus. PMID: 16778797
    5. GCH1 mutations in Japanese patients with DYT5 dystonia. In some of them, the GCH1 enzyme activity was proved to be impaired. PMID: 17101830
    6. The co-expression of GTP cyclohydrolase I (GCHI) with tyrosine hydroxylase (TH) indicates that TH is indeed active in human neurosecretory neurons. PMID: 17135716
    7. Demonstrate role for GFRP in regulating iNOS-mediated NO synthesis and suggest that the allosteric regulation of GTP-CH1 activity by GFRP may be an important mechanism regulating BH(4) and NO levels in vivo. PMID: 18372436
    8. crystal structure PMID: 11580249

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Nucleus membrane. Cytoplasm, cytosol.
  • 蛋白家族：
    GFRP family
  • 組織特異性：
    In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level).
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4194

    OMIM: 602437

    KEGG: hsa:2644

    STRING: 9606.ENSP00000260447

    UniGene: Hs.631717



主站蜘蛛池模板： 久久成人国产精品免费| 无码人妻丝袜在线视频红杏| 无码帝国www无码专区色综合 | 国产精品_国产精品_k频道| 7777奇米成人狠狠成人影视| 亚洲国产成人第一天堂| 极品美女扒开粉嫩小泬| 女人喷液抽搐高潮视频| 国产揉捏爆乳巨胸挤奶视频| 国产成人亚洲综合色婷婷秒播| 亚洲а∨精品天堂在线| 麻豆国产人妻欲求不满谁演的| 国产av久久人人澡人人爱| 日韩人妻不卡一区二区三区 | 精品国产av 无码一区二区三区 | 亚洲国产一区二区精品无码| 国产第一页浮力影院草草| 黄a大片av永久免费| 都市激情 在线 亚洲 国产| 97性无码区免费| 久久国产亚洲高清观看| 久久精品国产免费观看| 精品国产乱码久久久久app下载| 亚洲成aⅴ人最新无码| 后入到高潮免费观看| 老太脱裤子让老头玩xxxxx| 久久精品国产9久久综合| 四虎www永久在线精品| 亚洲欧美成人一区二区在线电影| 久久国产精品福利一区二区三区| 色综合天天综合天天更新| 中文字幕免费无码专区| 国产成人精品电影在线观看| 米奇影视第四色| 国产日产欧产精品精品免费| h无码精品3d动漫在线观看| 日日碰狠狠躁久久躁婷婷| 欧美日韩一区二区三区自拍| 久久99日韩国产精品久久99| 制服 丝袜 人妻 专区一本| 热re99久久精品国产66热|