在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GCHFR Antibody

GCHFR Antibody

  • 中文名稱：
    GCHFR兔多克隆抗體
  • 貨號(hào)：
    CSB-PA109145
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using GCHFR antibody.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GCHFR Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GCHFR
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from internal of Human GCHFR.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:50-1:100
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine.
  • 基因功能參考文獻(xiàn)：
    1. homozygous individuals for the TT haplotype were less likely to respond to the SSRI fluoxetine than to the nortriptyline suggesting a biological process through which GCHFR promoter variants might influence antidepressant response. PMID: 20351752
    2. Bacterial lipopolysaccharide down-regulates expression of GTP cyclohydrolase I feedback regulatory protein PMID: 11799107
    3. allosteric regulation of GTPCH-I activity in the cardiovascular system maybe an important mechanism regulating BH4 levels through GTPCH-I feedback regulatory protein signaling PMID: 15649650
    4. GFRP/GTPCHI axis functions in epidermal keratinocytes and melanocytes in the cytosol and nucleus. PMID: 16778797
    5. GCH1 mutations in Japanese patients with DYT5 dystonia. In some of them, the GCH1 enzyme activity was proved to be impaired. PMID: 17101830
    6. The co-expression of GTP cyclohydrolase I (GCHI) with tyrosine hydroxylase (TH) indicates that TH is indeed active in human neurosecretory neurons. PMID: 17135716
    7. Demonstrate role for GFRP in regulating iNOS-mediated NO synthesis and suggest that the allosteric regulation of GTP-CH1 activity by GFRP may be an important mechanism regulating BH(4) and NO levels in vivo. PMID: 18372436
    8. crystal structure PMID: 11580249

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Nucleus membrane. Cytoplasm, cytosol.
  • 蛋白家族：
    GFRP family
  • 組織特異性：
    In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level).
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4194

    OMIM: 602437

    KEGG: hsa:2644

    STRING: 9606.ENSP00000260447

    UniGene: Hs.631717



主站蜘蛛池模板： 中文字幕精品av乱码在线 | 亚洲国产精品久久人人爱| 国产精品久久久久久久妇| 亚洲国产成在人网站天堂| 免费视频成人片在线观看| 久久久久久无码精品人妻a片软件| 国语自产拍无码精品视频在线| 成人免费毛片内射美女-百度| 自拍偷自拍亚洲精品被多人伦好爽 | 天天干天天日夜夜操| 国产免费人成在线视频网站| 乱子伦农村xxxxbbb| 正在播放国产乱子伦最新视频| 亚洲人成色777777老人头| 久久久久夜夜夜精品国产| 欧美国产日韩a在线视频| 人人妻人人爽人人澡欧美一区| 伊人久久大香线蕉综合5g| 亚洲乱码中文字幕综合234 | 福利cosplayh裸体の福利| 国产精品日韩av在线播放| av狠狠色超碰丁香婷婷综合久久 | 国产欧美另类精品久久久| 免费无码久久成人网站入口| 国产精品喷浆| 日日噜噜噜夜夜爽爽狠狠| 特级无码毛片免费视频尤物| 亚洲色婷婷婷婷五月基地| 亚洲中文超碰中文字幕| 国精产品一区一区三区免费视频| 精品国产av 无码一区二区三区| 亚洲第一综合天堂另类专| 国产精品国产自线拍免费不卡| 天码欧美日本一道免费| 中国大陆精品视频xxxx| 国产精品丝袜黑色高跟鞋| 午夜理论片yy44880影院| 在线播放真实国产乱子伦| 色悠久久久久综合先锋影音下载| 99热精国产这里只有精品| 男人靠女人免费视频网站|