在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GCHFR Antibody

GCHFR Antibody

  • 中文名稱：
    GCHFR兔多克隆抗體
  • 貨號(hào)：
    CSB-PA109145
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using GCHFR antibody.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GCHFR Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GCHFR
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from internal of Human GCHFR.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:50-1:100
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine.
  • 基因功能參考文獻(xiàn)：
    1. homozygous individuals for the TT haplotype were less likely to respond to the SSRI fluoxetine than to the nortriptyline suggesting a biological process through which GCHFR promoter variants might influence antidepressant response. PMID: 20351752
    2. Bacterial lipopolysaccharide down-regulates expression of GTP cyclohydrolase I feedback regulatory protein PMID: 11799107
    3. allosteric regulation of GTPCH-I activity in the cardiovascular system maybe an important mechanism regulating BH4 levels through GTPCH-I feedback regulatory protein signaling PMID: 15649650
    4. GFRP/GTPCHI axis functions in epidermal keratinocytes and melanocytes in the cytosol and nucleus. PMID: 16778797
    5. GCH1 mutations in Japanese patients with DYT5 dystonia. In some of them, the GCH1 enzyme activity was proved to be impaired. PMID: 17101830
    6. The co-expression of GTP cyclohydrolase I (GCHI) with tyrosine hydroxylase (TH) indicates that TH is indeed active in human neurosecretory neurons. PMID: 17135716
    7. Demonstrate role for GFRP in regulating iNOS-mediated NO synthesis and suggest that the allosteric regulation of GTP-CH1 activity by GFRP may be an important mechanism regulating BH(4) and NO levels in vivo. PMID: 18372436
    8. crystal structure PMID: 11580249

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Nucleus membrane. Cytoplasm, cytosol.
  • 蛋白家族：
    GFRP family
  • 組織特異性：
    In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level).
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4194

    OMIM: 602437

    KEGG: hsa:2644

    STRING: 9606.ENSP00000260447

    UniGene: Hs.631717



主站蜘蛛池模板： 黑人大战欲求不满人妻| 久久精品国产精品久久久| 亚洲综合区小说区激情区| 国产一区二区三区不卡在线看| 欧美饥渴少妇xxxxx性| 先锋影音男人av资源| 可以直接免费观看的av网站| 久久久久女人精品毛片| 国产成人免费无码av在线播放| 天堂网www在线资源最新版| 亚洲精品偷拍影视在线观看| 日本熟妇浓毛| 欧美成人精品a∨在线观看| 尤物色综合欧美五月俺也去 | 热re99久久6国产精品免费| 最新精品国偷自产在线美女足| 国产成人精品一区二三区| 性一交一乱一伧国产女士spa| 国产aⅴ爽av久久久久久| 久久精品人人做人人爱爱漫画| 色www视频永久免费| 内射中出日韩无国产剧情| 樱花草在线社区www中国中文| 无码精品久久久天天影视| 男人j进女人p免费视频| 97超级碰碰人妻中文字幕| s级爆乳玩具酱国产vip皮裤| 亚洲a∨精品无码一区二区| 欧洲成人午夜精品无码区久久| 成人午夜精品无码区| 成人性三级欧美在线观看| 国产亚洲精品久久久久久禁果tv| 国产人成视频在线观看| 中文字幕丰满乱孑伦无码专区| 亚洲精品亚洲人成在线观看| 国产精品一区二区在线蜜芽tv| 亚洲性无码av在线dvd| 色欲色香天天天综合无码www| 在线看片无码永久av| 久久―日本道色综合久久| 永久免费观看国产裸体美女 |