在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GALR2 Antibody

GALR2 Antibody

  • 中文名稱：
    GALR2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA009224LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of A549 cells with CSB-PA009224LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) GALR2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    GALR2; GALNR2; Galanin receptor type 2; GAL2-R; GALR-2
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Galanin receptor type 2 protein (282-387AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，GALR2 Antibody (CSB-PA009224LA01HU)，的標(biāo)記方式是Non-conjugated。對于GALR2 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA009224LB01HU GALR2 Antibody, HRP conjugated ELISA
    FITC CSB-PA009224LC01HU GALR2 Antibody, FITC conjugated
    Biotin CSB-PA009224LD01HU GALR2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Receptor for the hormone galanin and GALP. Receptor for the hormone spexin-1. The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)).
  • 基因功能參考文獻(xiàn)：
    1. Study provides evidence that GAL and GALR1/2 genes were identified as aberrantly methylated in head and neck squamous cell carcinoma. PMID: 27685843
    2. GAL and its receptors, GALR1 and GALR2, play a role in head and neck squamous cell carcinoma tumorigenesis PMID: 26572146
    3. The G protein-coupled receptor GALR2 promotes angiogenesis in head and neck cancer PMID: 24568968
    4. In HEp-2 cells, GALR2-mediated apoptosis was caspase-independent. PMID: 24168112
    5. Activation of GalR2 leads to elevation of intracellular Ca(2+) due to Ca(2+) efflux from endoplasmic reticulum through IP3R sequentially opening BK alpha channels. PMID: 24602615
    6. The expression of GALR2 mRNA is lost in head and neck squamous cell carcinoma as a consequence of DNA methylation.Silencing of the GALR2 gene by methylation may be a critical event in head and neck squamous cell carcinoma. PMID: 24122450
    7. galanin receptor 2 promotes cell proliferation and survival, and promotes tumor growth, consistent with an oncogenic role for GALR2 in squamous cell carcinoma of the head and neck PMID: 21345369
    8. Elevated expression of galanin receptors in childhood neuroblastic tumors PMID: 11867941
    9. study indicates that a high level of GalR2 galanin receptor expression is able to inhibit cell proliferation and induce apoptosis in neuroblastoma cells PMID: 14592962
    10. There was no effect of GALR2 on alcoholism risk. PMID: 17083333
    11. point to GalR2 as a possible target for therapeuthic interventions in pheochromocytoma PMID: 18272487

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    Expressed abundantly within the central nervous system in both hypothalamus and hippocampus. In peripheral tissues, the strongest expression was observed in heart, kidney, liver, and small intestine.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4133

    OMIM: 603691

    KEGG: hsa:8811

    STRING: 9606.ENSP00000329684

    UniGene: Hs.666366



主站蜘蛛池模板： 少妇高潮无套内谢麻豆传| 一本久道久久综合狠狠爱| 青青久在线视观看视| 国内精品久久久久影院优| 漂亮人妻洗澡被公强 日日躁| 失禁大喷潮在线播放| 99re6热视频这里只精品首页| 免费va人成视频网站全| 久久国产av影片| 国产色xx群视频射精| 久久99久久99精品中文字幕| 在线天堂资源www在线污| 国产在线一区二区香蕉 在线| 国产熟女一区二区三区四区五区| 麻豆亚洲国产成人精品无码区| 欧美精品1卡二卡三卡四卡| 无码av永久免费专区麻豆| 动漫av纯肉无码av在线播放| 久久人妻无码中文字幕第一| 2021年精品国产福利在线| 精品人妻少妇一区二区| 亚洲一区二区三区香蕉| 国产精品国产av片国产| 四虎影库久免费视频| 日韩av无码中文无码不卡电影| 国产美女无遮挡裸色视频| 天堂av色综合久久天堂| 久久精品人人做人人爽| 久久久久人妻精品一区蜜桃| 色多多成视频人在线观看| 97狠狠狠狼鲁亚洲综合网| 亚洲aⅴ无码成人网站国产app| 国内揄拍国内精品人妻| 人妻熟女一区二区aⅴ水野朝阳| 中文无码久久精品| 国内揄拍国内精品少妇国语| 秋秋影视午夜福利高清| 无码国产一区二区免费| 国产乱人伦在线播放| 久久伊99综合婷婷久久伊| 99久久国产综合精品五月天喷水 |