在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GALR2 Antibody

  • 中文名稱:
    GALR2兔多克隆抗體
  • 貨號:
    CSB-PA070150
  • 規格:
    ¥1090
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    GALR2; GALNR2; Galanin receptor type 2; GAL2-R; GALR-2
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human GALR2.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Receptor for the hormone galanin and GALP. Receptor for the hormone spexin-1. The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i)).
  • 基因功能參考文獻:
    1. Study provides evidence that GAL and GALR1/2 genes were identified as aberrantly methylated in head and neck squamous cell carcinoma. PMID: 27685843
    2. GAL and its receptors, GALR1 and GALR2, play a role in head and neck squamous cell carcinoma tumorigenesis PMID: 26572146
    3. The G protein-coupled receptor GALR2 promotes angiogenesis in head and neck cancer PMID: 24568968
    4. In HEp-2 cells, GALR2-mediated apoptosis was caspase-independent. PMID: 24168112
    5. Activation of GalR2 leads to elevation of intracellular Ca(2+) due to Ca(2+) efflux from endoplasmic reticulum through IP3R sequentially opening BK alpha channels. PMID: 24602615
    6. The expression of GALR2 mRNA is lost in head and neck squamous cell carcinoma as a consequence of DNA methylation.Silencing of the GALR2 gene by methylation may be a critical event in head and neck squamous cell carcinoma. PMID: 24122450
    7. galanin receptor 2 promotes cell proliferation and survival, and promotes tumor growth, consistent with an oncogenic role for GALR2 in squamous cell carcinoma of the head and neck PMID: 21345369
    8. Elevated expression of galanin receptors in childhood neuroblastic tumors PMID: 11867941
    9. study indicates that a high level of GalR2 galanin receptor expression is able to inhibit cell proliferation and induce apoptosis in neuroblastoma cells PMID: 14592962
    10. There was no effect of GALR2 on alcoholism risk. PMID: 17083333
    11. point to GalR2 as a possible target for therapeuthic interventions in pheochromocytoma PMID: 18272487

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    Expressed abundantly within the central nervous system in both hypothalamus and hippocampus. In peripheral tissues, the strongest expression was observed in heart, kidney, liver, and small intestine.
  • 數據庫鏈接:

    HGNC: 4133

    OMIM: 603691

    KEGG: hsa:8811

    STRING: 9606.ENSP00000329684

    UniGene: Hs.666366



主站蜘蛛池模板: 国产欧美日韩综合精品一区二区| 初尝人妻少妇中文字幕| 一本本月无码-| 久久九九精品99国产精品| 无码国产69精品久久久久同性| 日韩高清亚洲日韩精品一区| 热99re久久精品国产首页免费| 男人吃奶摸下挵进去好爽| 在线视频国产制服丝袜| 欧美人与动另类xxxx| 私人毛片免费高清影视院| 欧美性生交xxxxx久久久| 亚洲精品制服丝袜四区| 亚洲色欲色欲天天天www| 激情av无码后入| 欧美性猛交xxxx黑人猛交| 久久人人爽人人爽人人片av东京热| 毛色毛片免费观看| 一本精品99久久精品77 | 亚洲自偷自拍另类12p| 国产精品美女久久久久| 日本精品人妻无码77777| 欧美日韩一区二区成人午夜电影| 国产综合精品久久丫| 永久免费无码av在线网站| 欧美午夜刺激影院| 人妻体内射精一区二区| 免费无遮挡禁18污污网站| 中文字幕精品亚洲无线码vr| 国内精品久久人妻互换| 久久综合狠狠综合久久综合88| 日本伊人色综合网| 中文字幕乱码人在线视频1区 | 久久婷婷久久一区二区三区| 国产欧美综合在线观看第十页| 影视av久久久噜噜噜噜噜三级| 国语自产少妇精品视频| 成人h动漫精品一区二区| 熟女俱乐部五十路六十路| 国产精品天干天干| 国产一区二区在线视频|