在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GALNT12 Antibody

GALNT12 Antibody

  • 中文名稱：
    GALNT12兔多克隆抗體
  • 貨號：
    CSB-PA814224LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA814224LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA814224LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) GALNT12 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GALNT12
  • 別名：
    Colorectal cancer susceptibility to 1 antibody; CRCS1 antibody; FLJ21212 antibody; GalNAc T12 antibody; GalNAc-T12 antibody; GalNAcT12 antibody; GALNT 12 antibody; Galnt12 antibody; GLT12_HUMAN antibody; Polypeptide GalNAc transferase 12 antibody; Polypeptide N acetylgalactosaminyltransferase 12 antibody; Polypeptide N-acetylgalactosaminyltransferase 12 antibody; pp GaNTase 12 antibody; pp-GaNTase 12 antibody; Protein UDP acetylgalactosaminyltransferase 12 antibody; Protein-UDP acetylgalactosaminyltransferase 12 antibody; UDP GalNAc polypeptide N acetylgalactosaminyltransferase 12 antibody; UDP GalNAc polypeptide N acetylgalactosaminyltransferase antibody; UDP N acetyl alpha D galactosamine polypeptide N acetylgalactosaminyltransferase 12 antibody; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 12 protein (1-272AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，GALNT12 Antibody (CSB-PA814224LA01HU)，的標記方式是Non-conjugated。對于GALNT12 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA814224LB01HU GALNT12 Antibody, HRP conjugated ELISA
    FITC CSB-PA814224LC01HU GALNT12 Antibody, FITC conjugated
    Biotin CSB-PA814224LD01HU GALNT12 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward non-glycosylated peptides such as Muc5AC, Muc1a and EA2, and no detectable activity with Muc2 and Muc7. Displays enzymatic activity toward the Gal-NAc-Muc5AC glycopeptide, but no detectable activity to mono-GalNAc-glycosylated Muc1a, Muc2, Muc7 and EA2. May play an important role in the initial step of mucin-type oligosaccharide biosynthesis in digestive organs.
  • 基因功能參考文獻：
    1. LOH analyses, glycosylation pattern tests and case-control studies, our results did not support the role of c.907G>A, p.(D303N) as a high-penetrance risk allele for polyposis CRC PMID: 29095867
    2. Results rule out GALNT12 as a major high familial colorectal cancer susceptibility gene. Additional studies are required to provide further evidence about its role as a moderate/low susceptibility gene in familial aggregation of cancer. PMID: 24115450
    3. we integrated different computational tools to perform the in silico analysis of clinically significant mutations (nsSNPs/single amino acid change) at both functional and structural levels, found in human GALNT3, GALNT8, GALNT12, and GALNT13 genes. PMID: 24038392
    4. Inherited deleterious variants in GALNT12 are associated with CRC susceptibility. PMID: 22461326
    5. cloning and characterization PMID: 12135769
    6. The expression of pp-GalNAc-T12 seems to be a negative marker especially of metastatic gastric and colorectal cancer PMID: 15557789
    7. inactivating GALNT12 mutations were identified as acquired somatic mutations in a set of 30 microsatellite stable colon tumors. PMID: 19617566

    顯示更多

    收起更多

  • 相關疾病：
    Colorectal cancer 1 (CRCS1)
  • 亞細胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 2 family, GalNAc-T subfamily
  • 組織特異性：
    Widely expressed at different levels of expression. Highly expressed in digestive organs such as small intestine, stomach, pancreas and colon. Expressed at intermediate level in testis, thyroid gland and spleen. Weakly expressed in whole brain, cerebral c
  • 數據庫鏈接：

    HGNC: 19877

    OMIM: 608812

    KEGG: hsa:79695

    STRING: 9606.ENSP00000364150

    UniGene: Hs.47099



主站蜘蛛池模板： 久久不见久久见免费影院国语| 中文字幕乱码在线人视频| 亚洲色精品三区二区一区| 国产二级一片内射视频插放| 永久黄网站色视频免费| 日韩乱码人妻无码中文字幕| 亚洲欧美日韩久久一区二区| 精品国产麻豆免费人成网站| 在线偷着国产精选视频| 永久免费精品成人网站| 日韩v亚洲v欧美v精品综合| 欧美老妇人与禽交| 欧美老熟妇xb水多毛多| 熟女少妇在线视频播放| 2021国产精品视频网站| 国产精品免费观看调教网| 69久久精品无码一区二区无码| www夜片内射视频在观看视频| 日本夜爽爽一区二区三区 | 亚洲欧洲美洲无码精品va| 天天做天天爱天天要天天| 亚洲国产品综合人成综合网站| 亚洲老熟女av一区二区在线播放| 亚洲午夜福利在线观看| 男人扒开女人内裤强吻桶进去| 国产无遮挡又黄又爽在线视频| 免费国产精品视频在线| 亚洲蜜桃v妇女| 丰满人妻妇伦又伦精品国产| 人牛交vide欧美xxxx| 成 人 免 费 黄 色| 免费看又色又爽又黄的国产软件| 少妇太爽了在线观看| 深夜福利啪啪片| 女人和拘做受全程看视频| 精品一卡2卡3卡4卡新区在线 | 久久精品国产99国产精偷| 亚洲成在人线在线播放无码vr| 男女免费观看在线爽爽爽视频| 综合 欧美 亚洲日本| 久久午夜无码鲁丝片秋霞|