在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GALNT12 Antibody

GALNT12 Antibody

  • 中文名稱：
    GALNT12兔多克隆抗體
  • 貨號：
    CSB-PA814224LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA814224LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA814224LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) GALNT12 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GALNT12
  • 別名：
    Colorectal cancer susceptibility to 1 antibody; CRCS1 antibody; FLJ21212 antibody; GalNAc T12 antibody; GalNAc-T12 antibody; GalNAcT12 antibody; GALNT 12 antibody; Galnt12 antibody; GLT12_HUMAN antibody; Polypeptide GalNAc transferase 12 antibody; Polypeptide N acetylgalactosaminyltransferase 12 antibody; Polypeptide N-acetylgalactosaminyltransferase 12 antibody; pp GaNTase 12 antibody; pp-GaNTase 12 antibody; Protein UDP acetylgalactosaminyltransferase 12 antibody; Protein-UDP acetylgalactosaminyltransferase 12 antibody; UDP GalNAc polypeptide N acetylgalactosaminyltransferase 12 antibody; UDP GalNAc polypeptide N acetylgalactosaminyltransferase antibody; UDP N acetyl alpha D galactosamine polypeptide N acetylgalactosaminyltransferase 12 antibody; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 12 protein (1-272AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，GALNT12 Antibody (CSB-PA814224LA01HU)，的標記方式是Non-conjugated。對于GALNT12 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA814224LB01HU GALNT12 Antibody, HRP conjugated ELISA
    FITC CSB-PA814224LC01HU GALNT12 Antibody, FITC conjugated
    Biotin CSB-PA814224LD01HU GALNT12 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward non-glycosylated peptides such as Muc5AC, Muc1a and EA2, and no detectable activity with Muc2 and Muc7. Displays enzymatic activity toward the Gal-NAc-Muc5AC glycopeptide, but no detectable activity to mono-GalNAc-glycosylated Muc1a, Muc2, Muc7 and EA2. May play an important role in the initial step of mucin-type oligosaccharide biosynthesis in digestive organs.
  • 基因功能參考文獻：
    1. LOH analyses, glycosylation pattern tests and case-control studies, our results did not support the role of c.907G>A, p.(D303N) as a high-penetrance risk allele for polyposis CRC PMID: 29095867
    2. Results rule out GALNT12 as a major high familial colorectal cancer susceptibility gene. Additional studies are required to provide further evidence about its role as a moderate/low susceptibility gene in familial aggregation of cancer. PMID: 24115450
    3. we integrated different computational tools to perform the in silico analysis of clinically significant mutations (nsSNPs/single amino acid change) at both functional and structural levels, found in human GALNT3, GALNT8, GALNT12, and GALNT13 genes. PMID: 24038392
    4. Inherited deleterious variants in GALNT12 are associated with CRC susceptibility. PMID: 22461326
    5. cloning and characterization PMID: 12135769
    6. The expression of pp-GalNAc-T12 seems to be a negative marker especially of metastatic gastric and colorectal cancer PMID: 15557789
    7. inactivating GALNT12 mutations were identified as acquired somatic mutations in a set of 30 microsatellite stable colon tumors. PMID: 19617566

    顯示更多

    收起更多

  • 相關疾病：
    Colorectal cancer 1 (CRCS1)
  • 亞細胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 2 family, GalNAc-T subfamily
  • 組織特異性：
    Widely expressed at different levels of expression. Highly expressed in digestive organs such as small intestine, stomach, pancreas and colon. Expressed at intermediate level in testis, thyroid gland and spleen. Weakly expressed in whole brain, cerebral c
  • 數據庫鏈接：

    HGNC: 19877

    OMIM: 608812

    KEGG: hsa:79695

    STRING: 9606.ENSP00000364150

    UniGene: Hs.47099



主站蜘蛛池模板： 精产国品一二三产品蜜桃| 国产精品乱码人妻一区二区三区| 国产精品乱码人妻一区二区三区| 在线毛片片免费观看| 99精品日本二区留学生| 日本xxxx裸体xxxx视频大全| 影视先锋av资源噜噜| 韩国精品一区二区三区四区| 亚洲第一狼人天堂久久| 无码专区6080yy国产电影| 亚洲一区二区三区av天堂| 四虎影成人精品a片| 日韩高清亚洲日韩精品一区| 精品无码一区在线观看| 蜜臀avwww国产天堂| 色偷偷人人澡人人爽人人模| 亚洲国产日韩欧美一区二区三区| 中文字幕丰满伦子无码| 久久久国产精品无码一区二区| 国产杨幂av在线播放| 少妇人妻偷人精品视蜜桃| 国产日韩欧美亚洲精品中字| 日韩精品专区在线影院重磅| 亚洲午夜成人av电影| 欧美在线看片a免费观看| 久久精品日韩av无码| 欧美日韩国产综合新一区| 精品国产一区二区三区香蕉| 亚洲国产精品综合久久网各| √天堂中文www官网在线| 无码日韩精品一区二区人妻| 色综合av综合无码综合网站| 大伊香蕉在线精品视频75| 老司机午夜福利av无码特黄a| 99久久99久久精品国产片| 天堂官网在线资源网| 强奷妇系列中文字幕| 午夜福利视频| 国产亚洲精品久久久久动漫| 国产综合一区二区三区黄页秋霞 | 中文国产成人精品久久久|