在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GALNT12 Antibody, FITC conjugated

GALNT12 Antibody, FITC conjugated

  • 中文名稱：
    GALNT12兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA814224LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) GALNT12 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    GALNT12
  • 別名：
    Colorectal cancer susceptibility to 1 antibody; CRCS1 antibody; FLJ21212 antibody; GalNAc T12 antibody; GalNAc-T12 antibody; GalNAcT12 antibody; GALNT 12 antibody; Galnt12 antibody; GLT12_HUMAN antibody; Polypeptide GalNAc transferase 12 antibody; Polypeptide N acetylgalactosaminyltransferase 12 antibody; Polypeptide N-acetylgalactosaminyltransferase 12 antibody; pp GaNTase 12 antibody; pp-GaNTase 12 antibody; Protein UDP acetylgalactosaminyltransferase 12 antibody; Protein-UDP acetylgalactosaminyltransferase 12 antibody; UDP GalNAc polypeptide N acetylgalactosaminyltransferase 12 antibody; UDP GalNAc polypeptide N acetylgalactosaminyltransferase antibody; UDP N acetyl alpha D galactosamine polypeptide N acetylgalactosaminyltransferase 12 antibody; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 12 protein (1-272AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward non-glycosylated peptides such as Muc5AC, Muc1a and EA2, and no detectable activity with Muc2 and Muc7. Displays enzymatic activity toward the Gal-NAc-Muc5AC glycopeptide, but no detectable activity to mono-GalNAc-glycosylated Muc1a, Muc2, Muc7 and EA2. May play an important role in the initial step of mucin-type oligosaccharide biosynthesis in digestive organs.
  • 基因功能參考文獻：
    1. LOH analyses, glycosylation pattern tests and case-control studies, our results did not support the role of c.907G>A, p.(D303N) as a high-penetrance risk allele for polyposis CRC PMID: 29095867
    2. Results rule out GALNT12 as a major high familial colorectal cancer susceptibility gene. Additional studies are required to provide further evidence about its role as a moderate/low susceptibility gene in familial aggregation of cancer. PMID: 24115450
    3. we integrated different computational tools to perform the in silico analysis of clinically significant mutations (nsSNPs/single amino acid change) at both functional and structural levels, found in human GALNT3, GALNT8, GALNT12, and GALNT13 genes. PMID: 24038392
    4. Inherited deleterious variants in GALNT12 are associated with CRC susceptibility. PMID: 22461326
    5. cloning and characterization PMID: 12135769
    6. The expression of pp-GalNAc-T12 seems to be a negative marker especially of metastatic gastric and colorectal cancer PMID: 15557789
    7. inactivating GALNT12 mutations were identified as acquired somatic mutations in a set of 30 microsatellite stable colon tumors. PMID: 19617566

    顯示更多

    收起更多

  • 相關疾病：
    Colorectal cancer 1 (CRCS1)
  • 亞細胞定位：
    Golgi apparatus membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Glycosyltransferase 2 family, GalNAc-T subfamily
  • 組織特異性：
    Widely expressed at different levels of expression. Highly expressed in digestive organs such as small intestine, stomach, pancreas and colon. Expressed at intermediate level in testis, thyroid gland and spleen. Weakly expressed in whole brain, cerebral c
  • 數據庫鏈接：

    HGNC: 19877

    OMIM: 608812

    KEGG: hsa:79695

    STRING: 9606.ENSP00000364150

    UniGene: Hs.47099



主站蜘蛛池模板： 无码色偷偷亚洲国内自拍| 老色鬼在线精品视频| 精品国产人妻一区二区三区| 亚洲中文字幕无码av永久| 伊人无码精品久久一区二区| 把腿张开老子臊烂你多p视频 | 亚洲色大成网站www永久网站| 97成人精品国语自产拍| 久久久久久九九精品久| 国产av国片精品jk制服丝袜| 国产极品美女高潮无套在线观看 | 日本高清一二三不卡区| √天堂资源中文| 人人妻人人澡人人爽人人精品| 精品国产av色一区二区深夜久久| 欧美成人精精品一区二区| 欧美人与禽z0zo牲伦交| 嫩草av久久伊人妇女超级a| 无码高潮少妇毛多水多水免费| 一区二区视频传媒有限公司| 久久精品娱乐亚洲领先| 久久人妻少妇嫩草av无码专区| 一二三四视频社区在线| 色惰日本视频网站www| 国产午夜精品久久久久免费视| 无码精品人妻一区二区三区免费看| 女人张开双腿让男人猛桶| 亚洲人成小说网站色在线观看| 色噜噜狠狠狠狠色综合久一| 欧美激情内射喷水高潮| 国产99青草视频在线播放视 | 日韩精品中文字幕无码一区| 久久视频在线视频精品| 中文字幕在线精品视频| 人妻激情另类乱人伦人妻| 国产美女视频免费观看的网站| 日韩在线看片免费人成视频播放 | 国产三级精品三级在专区| 国产无限次数成版人视频在线| 欧美精品videosbestsex日本 | 中文成人无码精品久久久动漫|