在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GABRA4 Antibody

  • 中文名稱:
    GABRA4兔多克隆抗體
  • 貨號:
    CSB-PA002616
  • 規(guī)格:
    ¥1090
  • 圖片:
    • Western Blot analysis of HepG2 cells using GABAA Rα4 Polyclonal Antibody
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    GABRA4
  • 別名:
    GABA(A) receptor subunit alpha 4 antibody; GABA(A) receptor subunit alpha-4 antibody; GABR A4 antibody; GABRA 4 antibody; Gabra4 antibody; Gamma aminobutyric acid (GABA) A receptor alpha 4 antibody; Gamma aminobutyric acid A receptor alpha 4 antibody; Gamma aminobutyric acid receptor alpha 4 subunit antibody; Gamma aminobutyric acid receptor subunit alpha 4 antibody; Gamma-aminobutyric acid receptor subunit alpha-4 antibody; GBRA4_HUMAN antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human GABAA Rα4.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • 基因功能參考文獻(xiàn):
    1. GABRA4 is associated with autism spectrum disorder in a dataset from Argentina. PMID: 26239769
    2. The ability of neurosteroids to modulate the phosphorylation and membrane insertion of alpha4 subunit-containing GABAARs may underlie the profound effects these endogenous signaling molecules have on neuronal excitability and behavior. PMID: 24778259
    3. Transgenic mice with the alpha4betadelta GABAA receptor subunit deletion show increased conditioned place preference, but not from delta-deficient or alpha4-deficient knockout mice. PMID: 24431441
    4. The pathway by which GABRA2 initially confers risk for eventual alcohol problems begins with a predisposition to sensation-seeking early in adolescence. PMID: 23561058
    5. Association between premenstrual symptom severity and two genes from the gamma-aminobutyric acid (GABA) pathway: steroid-5-alpha-reductase, alpha polypeptide 1 (SRD5A1) and gamma-aminobutyric acid receptor subunit alpha-4 (GABRA4). PMID: 22273344
    6. single nucleotide polymorphisms studied in the GABRA4, GABRE, and GABRQ genes are not related to the risk for familial ET. PMID: 21422964
    7. truncated alpha 4 N-terminus may play a post-translational regulatory role in intracellular folding/glycosylation/assembly of the alpha 4 subunit PMID: 12242096
    8. GABRA4 is involved in the etiology of autism and potentially increases autism risk through interaction with GABRB1. PMID: 16080114
    9. These results confirmed our earlier findings, indicating GABRA4 and GABRB1 as genes contributing to autism susceptibility, extending the effect to multiple ethnic groups and suggesting seizures as a stratifying phenotype. PMID: 16770606
    10. alpha4beta3gamma2L receptors have unique kinetic properties that limit the range of GABA applications to which they can respond maximally. PMID: 17124266
    11. Only two of the newly genotyped SNPs, rs10517173, rs16851647, were associated with nicotine dependence (observed P-values of 0.002, corrected FDR-BH P-values of 0.02). However, these SNPs were in complete LD with each other and with rs11731576. PMID: 19207358
    12. Lower delta mRNA levels in schizophrenia might reflect a reduced number of alpha(1)beta(x)delta GABA(A) receptors that could contribute to deficient tonic inhibition and prefrontal cortical dysfunction in schizophrenia. PMID: 19289452

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRA4 sub-subfamily
  • 數(shù)據(jù)庫鏈接:

    HGNC: 4078

    OMIM: 137141

    KEGG: hsa:2557

    STRING: 9606.ENSP00000264318

    UniGene: Hs.248112



主站蜘蛛池模板: 国产精品无码av片在线观看播 | 国产乡下妇女做爰| 午夜无码乱码在线观看| 丰满岳乱妇在线观看中字| 女人夜夜春高潮爽a∨片传媒 | 精品一区二区三区在线视频| 天天摸夜夜摸夜夜狠狠摸| 欧美孕妇乳喷奶水在线观看| 秋霞无码久久久精品交换| 午夜精品射精入后重之免费观看| 久久精品aⅴ无码中文字字幕蜜桃 午夜成人鲁丝片午夜精品 | 色综合天天综合天天更新| 日韩欧美国产一区精品| 免费人成小说在线观看网站 | 精品服丝袜无码视频一区 | 精品夜夜澡人妻无码av蜜桃| 亚洲和欧洲一码二码区别7777| 国产精品爽爽久久久久久无码| 久久日本片精品aaaaa国产| 人妻丰满熟妇aⅴ无码| 国产又黄又刺激又高潮的网站| 免费毛片手机在线播放| 男女猛烈无遮挡免费视频在线观看| 亚洲国产精品久久精品| 日本无遮挡真人祼交视频| 又黄又湿啪啪响18禁| 亚洲中文字幕无码久久| 4hu四虎永久在线观看| 国产精品无码综合区| a毛片免费全部播放| 精品1卡二卡三卡四卡老狼| 麻花豆传媒剧国产免费mv入口| 日韩经典精品无码一区| 国产偷国产偷亚州清高app| 国产成人免费无码视频在线观看| av狠狠色超碰丁香婷婷综合久久 | 丰满的少妇hd高清中文字幕| 日韩一欧美内射在线观看| 日韩 无码 偷拍 中文字幕| 亚洲精品无码你懂的| 少妇无码av无码专区|