在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

GABRA4 Antibody

  • 中文名稱:
    GABRA4兔多克隆抗體
  • 貨號:
    CSB-PA009683
  • 規格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from HepG2 cells, using GABRA4 antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) GABRA4 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    GABRA4
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from internal of Human GABRA4.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • 基因功能參考文獻:
    1. GABRA4 is associated with autism spectrum disorder in a dataset from Argentina. PMID: 26239769
    2. The ability of neurosteroids to modulate the phosphorylation and membrane insertion of alpha4 subunit-containing GABAARs may underlie the profound effects these endogenous signaling molecules have on neuronal excitability and behavior. PMID: 24778259
    3. Transgenic mice with the alpha4betadelta GABAA receptor subunit deletion show increased conditioned place preference, but not from delta-deficient or alpha4-deficient knockout mice. PMID: 24431441
    4. The pathway by which GABRA2 initially confers risk for eventual alcohol problems begins with a predisposition to sensation-seeking early in adolescence. PMID: 23561058
    5. Association between premenstrual symptom severity and two genes from the gamma-aminobutyric acid (GABA) pathway: steroid-5-alpha-reductase, alpha polypeptide 1 (SRD5A1) and gamma-aminobutyric acid receptor subunit alpha-4 (GABRA4). PMID: 22273344
    6. single nucleotide polymorphisms studied in the GABRA4, GABRE, and GABRQ genes are not related to the risk for familial ET. PMID: 21422964
    7. truncated alpha 4 N-terminus may play a post-translational regulatory role in intracellular folding/glycosylation/assembly of the alpha 4 subunit PMID: 12242096
    8. GABRA4 is involved in the etiology of autism and potentially increases autism risk through interaction with GABRB1. PMID: 16080114
    9. These results confirmed our earlier findings, indicating GABRA4 and GABRB1 as genes contributing to autism susceptibility, extending the effect to multiple ethnic groups and suggesting seizures as a stratifying phenotype. PMID: 16770606
    10. alpha4beta3gamma2L receptors have unique kinetic properties that limit the range of GABA applications to which they can respond maximally. PMID: 17124266
    11. Only two of the newly genotyped SNPs, rs10517173, rs16851647, were associated with nicotine dependence (observed P-values of 0.002, corrected FDR-BH P-values of 0.02). However, these SNPs were in complete LD with each other and with rs11731576. PMID: 19207358
    12. Lower delta mRNA levels in schizophrenia might reflect a reduced number of alpha(1)beta(x)delta GABA(A) receptors that could contribute to deficient tonic inhibition and prefrontal cortical dysfunction in schizophrenia. PMID: 19289452

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRA4 sub-subfamily
  • 數據庫鏈接:

    HGNC: 4078

    OMIM: 137141

    KEGG: hsa:2557

    STRING: 9606.ENSP00000264318

    UniGene: Hs.248112



主站蜘蛛池模板: 真人性生交免费视频| 亚洲精品乱码久久久久久金桔影视| 国产乱人伦在线播放| 国产乱码日产精品bd| 18禁裸男晨勃露j毛网站| 亚洲线精品一区二区三区影音先锋| 激情综合色综合啪啪五月丁香| 97在线精品视频免费| 午夜131美女爱做视频| 日本丶国产丶欧美色综合| 久久大香香蕉国产| 午夜国产免费视频亚洲| 日韩国产成人无码av毛片蜜柚| 蜜臀av性久久久久蜜臀aⅴ麻豆| 国产97色在线 | 日韩| 久久青青草原国产毛片| 国产成人精品亚洲精品| 67194熟妇在线观看线路| 长腿校花无力呻吟娇喘| 国产乱人伦偷精品视频aaa| 亚洲人成图片小说网站| 忍不住的亲子中文字幕| 久久精品亚洲精品国产色婷| 狠狠色丁香久久婷婷综合_中| 上司人妻互换中文字幕| 亚洲一线二线三线写真| 亚洲国产成人最新精品| 欧美精品色婷婷五月综合| 日本不卡高字幕在线2019| 久久精品99av高久久精品| 亚洲色无码中文字幕在线| 无码高潮爽到爆的喷水视频| 精品久久久久久亚洲精品| 国产精品麻豆aⅴ人妻 | 亚洲综合av一区二区三区| 久久精品国产99精品亚洲| 国产午夜无码片在线观看| 亚洲国产一区二区三区波多野结衣 | 在线观看无码av网址| 一个人看的日本hd免费| 亚洲一二三四2021不卡|