在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. G3BP2 Antibody

G3BP2 Antibody

  • 中文名稱：
    G3BP2兔多克隆抗體
  • 貨號：
    CSB-PA002603
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of A549 cells using G3BP2 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    G3BP 2 antibody; G3BP-2 antibody; G3BP2 antibody; G3BP2_HUMAN antibody; GAP SH3 domain binding protein 2 antibody; GAP SH3 domain-binding protein 2 antibody; GTPase activating protein (SH3 domain) binding protein 2 antibody; Ras GTPase activating protein SH3 domain binding protein 2 antibody; Ras GTPase-activating protein-binding protein 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human G3BP2.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Scaffold protein that plays an essential role in cytoplasmic stress granule formation which acts as a platform for antiviral signaling.
  • 基因功能參考文獻：
    1. High G3BP2 levels worsened prognosis in breast cancer. Cell lines with lower G3BP2 levels required substantially higher cell numbers to form tumors in NOD/SCID mice. G3BP2 regulates SART3, Nanog, and Oct-4 expression levels and may be responsible for the maintenance of subpopulations of breast cancer cells with long-term proliferative properties.G3BP2 is important in breast tumor initiation. PMID: 28096337
    2. Translocation of p53 is regulated by androgen-dependent sumoylation mediated by the G3BP2-interacting SUMO-E3 ligase, RanBP2. G3BP2 knockdown results in reduced tumor growth and increased nuclear p53 accumulation in mouse xenograft models of prostate cancer with or without long-term androgen deprivation. PMID: 28692047
    3. FGDF peptide binds and changes conformation of the protruding N-terminal residues by providing hydrophobic interactions to a symmetry related molecule that facilitated crystallization of the G3BP2 isoform. PMID: 26410532
    4. G3BP1, G3BP2 and CAPRIN1 are required for translation of interferon stimulated mRNAs and are targeted by a dengue virus non-coding RNA. PMID: 24992036
    5. Reveal a TWIST1-G3BP2 mechanotransduction pathway that responds to biomechanical signals from the tumour microenvironment to drive EMT, invasion and metastasis. PMID: 25893917
    6. Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication. PMID: 25653451
    7. both G3BP1 and G3BP2 play a role in the formation of SGs in various human cells and thereby recovery from these cellular stresses. PMID: 23279204
    8. Data show that the nsP3/G3BP interaction also blocks stress granules (SGs) induced by other stresses than virus infection. PMID: 23087212
    9. first evidence of direct interactions between PKCalpha and G3BP2 and that PKCalpha can phosphorylate G3BP2. PMID: 22536444
    10. We showed that just four genes, G3BP2, SCARB2, CSNK1A1 and SPRR2B, can classify patients as presence of lymph node metastasis negative or positive, with 80.0% accuracy. PMID: 21985131
    11. Both G3BP1 and G3BP2 isoforms may act as negative regulators of tumor suppressor protein p53. PMID: 17297477

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cytoplasm, Stress granule.
  • 數據庫鏈接：

    HGNC: 30291

    KEGG: hsa:9908

    STRING: 9606.ENSP00000352738

    UniGene: Hs.303676



主站蜘蛛池模板： 亚洲人成在线观看网站不卡| 日本欧美视频在线观看| 蜜臀av夜夜澡人人爽人人| 精品人妻无码一区二区三区换脸| 少妇做爰免费视频网站| 国产成人久久综合77777| 日本韩国的免费观看视频| 亚洲精品无码永久中文字幕| 国产精品亚洲专区无码破解版| 成人午夜福利视频镇东影视| 都市激情 在线 亚洲 国产| 无遮挡午夜男女xx00动态| 久久精品国产99久久久小说| 男女边吃奶边做边爱视频| 337p大胆啪啪私拍人体| 国产成人人人97超碰超爽8| 日韩av无码社区一区二区三区| 国产亚洲va在线电影| av无码久久久久不卡网站蜜桃| 乱女伦露脸对白在线播放| 亚洲色无码专区在线观看精品| 精品国产你懂的在线观看 | 亚州性无码不卡免费视频| 日本高清色倩视频在线观看| 男女做爰真人视频直播| 两根大肉大捧一进一出好爽视频| 成年网站未满十八禁视频天堂| 狠狠做五月深爱婷婷伊人| 影音先锋女人av鲁色资源网久久| 麻豆久久久9性大片| 日本少妇内射视频播放舔| 久久人妻少妇嫩草av| 亚洲精品久久久久久中文字幕| 成人无码男男gv在线观看网站| 免费观看男女性高视频| 忘忧草在线社区www中国中文| 国产97在线 | 中文| 国产成人手机高清在线观看网站| 2021亚洲国产成a在线| 久久99国产亚洲高清观看首页| 成年片色大黄全免费软件到 |