在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

G3BP2 Antibody

  • 中文名稱:
    G3BP2兔多克隆抗體
  • 貨號:
    CSB-PA296678
  • 規格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from A549 cells, HUVEC cells and HeLa cells, using G3BP2 antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) G3BP2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from C-terminal of Human G3BP2.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Scaffold protein that plays an essential role in cytoplasmic stress granule formation which acts as a platform for antiviral signaling.
  • 基因功能參考文獻:
    1. High G3BP2 levels worsened prognosis in breast cancer. Cell lines with lower G3BP2 levels required substantially higher cell numbers to form tumors in NOD/SCID mice. G3BP2 regulates SART3, Nanog, and Oct-4 expression levels and may be responsible for the maintenance of subpopulations of breast cancer cells with long-term proliferative properties.G3BP2 is important in breast tumor initiation. PMID: 28096337
    2. Translocation of p53 is regulated by androgen-dependent sumoylation mediated by the G3BP2-interacting SUMO-E3 ligase, RanBP2. G3BP2 knockdown results in reduced tumor growth and increased nuclear p53 accumulation in mouse xenograft models of prostate cancer with or without long-term androgen deprivation. PMID: 28692047
    3. FGDF peptide binds and changes conformation of the protruding N-terminal residues by providing hydrophobic interactions to a symmetry related molecule that facilitated crystallization of the G3BP2 isoform. PMID: 26410532
    4. G3BP1, G3BP2 and CAPRIN1 are required for translation of interferon stimulated mRNAs and are targeted by a dengue virus non-coding RNA. PMID: 24992036
    5. Reveal a TWIST1-G3BP2 mechanotransduction pathway that responds to biomechanical signals from the tumour microenvironment to drive EMT, invasion and metastasis. PMID: 25893917
    6. Stress granule components G3BP1 and G3BP2 play a proviral role early in Chikungunya virus replication. PMID: 25653451
    7. both G3BP1 and G3BP2 play a role in the formation of SGs in various human cells and thereby recovery from these cellular stresses. PMID: 23279204
    8. Data show that the nsP3/G3BP interaction also blocks stress granules (SGs) induced by other stresses than virus infection. PMID: 23087212
    9. first evidence of direct interactions between PKCalpha and G3BP2 and that PKCalpha can phosphorylate G3BP2. PMID: 22536444
    10. We showed that just four genes, G3BP2, SCARB2, CSNK1A1 and SPRR2B, can classify patients as presence of lymph node metastasis negative or positive, with 80.0% accuracy. PMID: 21985131
    11. Both G3BP1 and G3BP2 isoforms may act as negative regulators of tumor suppressor protein p53. PMID: 17297477

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cytoplasm, Stress granule.
  • 數據庫鏈接:

    HGNC: 30291

    KEGG: hsa:9908

    STRING: 9606.ENSP00000352738

    UniGene: Hs.303676



主站蜘蛛池模板: 国产 国语对白 露脸| 国产av麻豆mag剧集| 日韩乱码人妻无码系列中文字幕 | 欧美粗大猛烈老熟妇| 亚洲国产精品13p| 亚洲国产av无码综合原创国产| 男女性高爱潮免费观看| 5858s亚洲色大成网站www| 欧美日韩在线第一页免费观看| 日本最大色倩网站www| 久久免费午夜福利院| 性色欲情网站| 精品日本一区二区免费视频| 无码人妻少妇久久中文字幕蜜桃| 国产台湾无码av片在线观看 | 亚洲日本一区二区一本一道| 亚洲午夜免费福利视频| 精品香蕉久久久午夜福利| 国产片免费福利片永久| 久久久久国产精品人妻aⅴ果冻| 国产成人无码a区精油按摩| 亚洲人成亚洲精品| 人妻熟女一区二区aⅴ图片| 无码人妻天天拍夜夜爽| 特级西西人体444www高清大胆| 国内精品伊人久久久久影院麻豆| 无码精品人妻一区二区三区人妻斩| 中文天堂在线资源www| 久久精品中文字幕有码| 人妻无码中文久久久久专区| 特级做a爰片毛片免费看108 | 亚洲 日本 欧美 中文字幕| 亚洲精品成人av在线观看爽翻天| 国产亚洲欧美在线专区| 精品产区wnw2544| 色又黄又爽18禁免费视频| 人妻中出无码一区二区三区| 伊人久久大香线蕉无码| 最近2019中文字幕大全第二页| 成年片色大黄全免费软件到| 亚洲国产老鸭窝一区二区三区|