在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FPR3 Antibody

  • 中文名稱:
    FPR3兔多克隆抗體
  • 貨號:
    CSB-PA008407
  • 規格:
    ¥1090
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    FPR3; FPRH1; FPRL2; N-formyl peptide receptor 3; FMLP-related receptor II; FMLP-R-II; Formyl peptide receptor-like 2
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the C-terminal region of Human FPRL2.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    IF, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    IF 1:200-1:1000
    ELISA 1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Acts as a receptor for humanin.
  • 基因功能參考文獻:
    1. The demonstrated proper folding and functionality of the cell-free produced human FPR3 opens a new avenue for the fast and efficient generation of human FPRs (and even other GPCRs) for structural and functional analysis. PMID: 23746112
    2. transcriptional variations of FPR3 occur by an alternative promoter during primate evolution. PMID: 21717223
    3. F2L peptide, derived from the processing of nanomolar concentrations of heme-binding protein (HEBP)1, is active on FPR3 and able to induce recruitment of FPR3-expressing monocytes, macrophages, and mouse neutrophils PMID: 21709160
    4. Results show that uPAR expression regulates the adhesive and migratory ability of CXCR4-expressing cells through a mechanism involving fMLP receptors and alpha-v integrins. PMID: 20972812
    5. Human dendritic cells express functional FPRL2 throughout maturation. FPRL2 & its endogenous ligand may be involved in regulating DC trafficking during Ag uptake & processing s well as the T-cell-stimulating phase of the immune responses. PMID: 12223529
    6. Activation of FPRL2 inhibits lipopolysaccharide-induced dendritic cell maturation. PMID: 16002663
    7. However, F2L inhibits formyl peptide receptor (FPR) and FPRL1 activities, resulting in the inhibition of intracellular calcium increases, and superoxide generation induced by N-formyl-Met-Leu-Phe, MMK-1, or Trp-Lys-Tyr-Met-Val-d-Met in neutrophils. PMID: 17577578
    8. FPRL2 is expressed and functional in macrophages differentiated from monocytes in vitro in different conditions PMID: 19342677
    9. Human monocytes express FPR1, FPR2, and FPR3; human neutrophils express FPR1 and FPR2, but not FPR3. PMID: 19843937

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    Detected in various tissues with highest expression in lung.
  • 數據庫鏈接:

    HGNC: 3828

    OMIM: 136539

    KEGG: hsa:2359

    STRING: 9606.ENSP00000341821

    UniGene: Hs.445466



主站蜘蛛池模板: 中文字幕高清免费日韩视频在线| 中文国产乱码在线人妻一区二区| 2020最新无码国产在线观看| 人人莫人人擦人人看| 2018天天拍拍天天爽视频| 99精品众筹模特自拍视频| 久久国产劲爆∧v内射| 18禁无码永久免费无限制网站| 人妻无码少妇一区二区| 蜜桃av麻豆av果冻传媒| 精品少妇一区二区三区免费观| 山东熟女啪啪哦哦叫| 国产揉捏爆乳巨胸挤奶视频| 女人被躁到高潮免费视频软件| 国产69精品久久久久乱码韩国| 久久国产福利国产秒拍| 久久精品国产最新地址| 免费看撕开奶罩揉吮奶头视频 | 日韩加勒比一本无码精品| 中日韩产精品1卡二卡三卡| 香蕉久久国产av一区二区| 久无码久无码av无码| 日韩国产精品无码一区二区三区| av无码中出一区二区三区 | 国产看黄网站又黄又爽又色| 2012中文字幕在线视频| 日本欧美一区二区免费视频| 欧美专区另类专区在线视频| 无遮挡又黄又刺激的视频| 亚洲熟妇无码乱子av电影| 日本久久综合久久综合| 国产av无码精品色午夜| 同性男男黄g片免费网站| 国产精品自在线拍国产| 无线日本视频精品| 亚洲妇女自偷自偷图片| 亚洲国产精品成人久久蜜臀| 少妇无套内谢久久久久| 男女裸交无遮挡啪啪激情试看| 人妻熟女一区二区aⅴ清水理纱| 亚洲第一成人网站|