在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FPR3 Antibody

  • 中文名稱:
    FPR3兔多克隆抗體
  • 貨號:
    CSB-PA297988
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA297988(FPR3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA297988(FPR3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    FPR3; FPRH1; FPRL2; N-formyl peptide receptor 3; FMLP-related receptor II; FMLP-R-II; Formyl peptide receptor-like 2
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthetic peptide of Human FPR3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Acts as a receptor for humanin.
  • 基因功能參考文獻:
    1. The demonstrated proper folding and functionality of the cell-free produced human FPR3 opens a new avenue for the fast and efficient generation of human FPRs (and even other GPCRs) for structural and functional analysis. PMID: 23746112
    2. transcriptional variations of FPR3 occur by an alternative promoter during primate evolution. PMID: 21717223
    3. F2L peptide, derived from the processing of nanomolar concentrations of heme-binding protein (HEBP)1, is active on FPR3 and able to induce recruitment of FPR3-expressing monocytes, macrophages, and mouse neutrophils PMID: 21709160
    4. Results show that uPAR expression regulates the adhesive and migratory ability of CXCR4-expressing cells through a mechanism involving fMLP receptors and alpha-v integrins. PMID: 20972812
    5. Human dendritic cells express functional FPRL2 throughout maturation. FPRL2 & its endogenous ligand may be involved in regulating DC trafficking during Ag uptake & processing s well as the T-cell-stimulating phase of the immune responses. PMID: 12223529
    6. Activation of FPRL2 inhibits lipopolysaccharide-induced dendritic cell maturation. PMID: 16002663
    7. However, F2L inhibits formyl peptide receptor (FPR) and FPRL1 activities, resulting in the inhibition of intracellular calcium increases, and superoxide generation induced by N-formyl-Met-Leu-Phe, MMK-1, or Trp-Lys-Tyr-Met-Val-d-Met in neutrophils. PMID: 17577578
    8. FPRL2 is expressed and functional in macrophages differentiated from monocytes in vitro in different conditions PMID: 19342677
    9. Human monocytes express FPR1, FPR2, and FPR3; human neutrophils express FPR1 and FPR2, but not FPR3. PMID: 19843937

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    Detected in various tissues with highest expression in lung.
  • 數據庫鏈接:

    HGNC: 3828

    OMIM: 136539

    KEGG: hsa:2359

    STRING: 9606.ENSP00000341821

    UniGene: Hs.445466



主站蜘蛛池模板: 亚洲精品美女久久久久久久| 丰满少妇夜夜爽爽高潮水| 国产精品免费久久久久电影| 99热精品久久只有精品| 色综合色综合久久综合频道88| 久久天天躁夜夜躁狠狠85台湾| 国产成人精品久久一区二区| 日本熟妇厨房bbw| 欧美综合自拍亚洲综合图| 国产人妻aⅴ色偷| 精品久久久久久中文墓无码| 国产成人精品无码a区在线观看| 免费无码毛片一区二区app| 亚洲乱码卡一卡二卡新区豆| 久久久精品456亚洲影院| 亚洲成av人片一区二区三区| 国产对白老熟女正在播放| 永久免费观看的毛片手机视频| 成人免费无码视频在线网站| 嫩草av久久伊人妇女超级a| www片香蕉内射在线88av8| 手机看黄av免费网址| 精选国产av精选一区二区三区| 国产女人被狂躁到高潮小说| 国产精品一国产精品| 亚洲熟妇无码av不卡在线观看| 水蜜桃av导航| 久久99精品久久久久久秒播| 国产高清不卡无码视频| 亚洲国产精品无码专区影院| 无码高潮爽到爆的喷水视频| 欧美变态暴力牲交videos| 精品无码一区在线观看| 成人区人妻精品一区二区不卡网站 | 亚洲国产成人高清影视| 天堂资源最新在线| 色综合久久久久综合体桃花网| 清纯唯美经典一区二区| 欧美日韩在大午夜爽爽影院| 人妻丰满熟妇av无码区不卡| 天堂8а√中文在线官网|