在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FMOD Antibody

  • 中文名稱:
    FMOD兔多克隆抗體
  • 貨號:
    CSB-PA008755GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    FMOD
  • 別名:
    Collagen binding 59 kDa protein antibody; Collagen-binding 59 kDa protein antibody; Fibromodulin antibody; Fibromodulin precursor antibody; Fibromodulin proteoglycan antibody; FM antibody; FMOD antibody; FMOD_HUMAN antibody; Keratan sulfate proteoglycan fibromodulin antibody; KSPG fibromodulin antibody; SLRR2E antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human FMOD
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
  • 基因功能參考文獻:
    1. The results of luciferase reporter assay and methylation-specific PCR (MSP) demonstrated that GDNF facilitated the demethylation of the FMOD promoter. PMID: 30176167
    2. crystal structures at ~2.2A resolution of human fibromodulin and chondroadherin. PMID: 28215822
    3. we found that secreted FMOD as an important regulator of glioma cell migration downstream of TGF-beta1 pathway and forms a potential basis for therapeutic intervention in GBM. PMID: 27212030
    4. The small leucine rich proteoglycan fibromodulin is overexpressed in human prostate epithelial cancer cell lines in culture and human prostate cancer tissue. PMID: 26600400
    5. expression levels distinguish chronic lymphocytic leukemia B cells from normal B lymphocytes PMID: 26318878
    6. The data suggest a fibromodulin-modulated collagen cross-linking mechanism where fibromodulin binds to a specific part of the collagen domain and also forms a complex with lysyl oxidase, targeting the enzyme toward specific cross-linking sites. PMID: 26893379
    7. fibromodulin is involved in the inflammatory processes that characterize atherosclerotic plaque vulnerability PMID: 26125412
    8. The results suggest that regions within FMOD is associated with ACL injury susceptibility and that genetic sequence variability within genes encoding proteoglycans may potentially modulate the ligament fibril properties. PMID: 24552666
    9. Melanocyte-secreted factor FMOD is a key regulator of angiogenesis. PMID: 24355922
    10. Associations between higher fibomodulin gene expression and risk factors in chronic lymphocytic leukemia. PMID: 22099931
    11. Hepatic fibromodulin activates hepatic stellate cells and promotes collagen I deposition, which leads to liver fibrosis. PMID: 22138190
    12. lumican and fibromodulin display different behaviors and that lumican may promote regeneration of the TMJ after degeneration and deformation induced by IL-1 beta. PMID: 22073367
    13. study shows (1) a detailed description of ectopic ossification (EO) formed by Bgn, Fmod or combined depletion, (2) the role of exercise in modulating EO and (3) that Bgn and Fmod are critical in controlling motor function. PMID: 19422643
    14. Fibromodulin is shown for the first time to be naturally processed and presented as a tumor-associated antigen in primary chronic lymphocytic leukemia cells, enabling the expansion of autologous tumor-specific T cells. PMID: 15471955
    15. Fibromodulin has a role in progression of B-cell chronic lymphocytic leukemia and mantle cell lymphoma PMID: 15741214
    16. fibromodulin activates the classical pathway of complement by directly binding C1q PMID: 16046396
    17. complement control protein 6-8 is able to interact with DNA and necrotic cells, but in contrast the His-384 allotype binds these ligands more strongly than the Tyr-384 variant PMID: 17293598
    18. The collagen-binding Glu-353 and Lys-355 residues in fibromodulin are exposed on the exterior of the beta-sheet-loop structure of the leucine-rich repeat, which resembles the location of interacting residues in other leucine-rich repeat proteins. PMID: 17623650
    19. Fibromodulin gene is constantly expressed in human epidermal keratinocytes. PMID: 18448071
    20. Specific decorin and fibromodulin core protein fragments in degenerate meniscus and/or human articular cartilage may be of value as biomarkers of disease. PMID: 18620607
    21. CD200 blockade was further shown to stimulate antigen-specific T cell responses towards the CLL-associated antigen fibromodulin PMID: 18838168
    22. Homologous sequence in lumican and fibromodulin leucine-rich repeat 5-7 competes for collagen binding. PMID: 19008226
    23. Ultraviolet B and A irradiation induce FMOD expression in fibroblasts in vitro. PMID: 19041686
    24. differentially expressed in mesenchymal stromal cell subset with reduced differentiation potential PMID: 19242838
    25. tyrosine sulfate-rich domains of the LRR proteins fibromodulin and osteoadherin bind motifs of basic clusters in a variety of heparin-binding proteins, including bioactive factors PMID: 19700767

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Small leucine-rich proteoglycan (SLRP) family, SLRP class II subfamily
  • 數據庫鏈接:

    HGNC: 3774

    OMIM: 600245

    KEGG: hsa:2331

    STRING: 9606.ENSP00000347041

    UniGene: Hs.519168



主站蜘蛛池模板: 日本另类αv欧美另类aⅴ| 色www永久免费视频首页| 男女无遮挡猛进猛出免费观看视频| 午夜免费啪在线观看视频| 无码人妻丰满熟妇奶水区码 | 日本丰满护士爆乳xxxx| 亚洲成a人片在线观看日本| 女女互磨互喷水高潮les呻吟| 亚洲中文字幕无码专区| 国产无限次数成版人视频在线| 亚洲精品伊人久久久大香| 精品亚洲成a人在线观看| 欧美人与动牲交zooz乌克兰| 亚洲美女高清无水av| 色琪琪av中文字幕一区二区| 国产二级一片内射视频插放| 亚洲人成色777777精品音频| 久久天天躁狠狠躁夜夜躁2012| 亚洲卡一卡二乱码新区仙踪| 欧美乱大交xxxxx潮喷l头像| 精品国产免费一区二区三区| 成人午夜无码精品免费看 | 青青草大香焦在线综合视频 | 手机看片精品国产福利 | 欧洲乱码伦视频免费| 国产午夜亚洲精品区| 中文字幕av伊人av无码av狼人| 开心五月激情综合婷婷色| 国产欧美日韩精品a在线观看| 久热这里只精品99国产6-99re视…| 亚洲深深色噜噜狠狠网站| 亚洲aⅴ男人的天堂在线观看 | 午夜福利理论片在线观看| 中文字日产幕乱五区| 免费做a爰片久久毛片a片下载| 无码视频一区二区三区| 尤物av无码色av无码| 国产午夜片无码区在线观看爱情网| 色婷婷亚洲一区二区综合| 亚洲日韩乱码一区二区三区四区| 精品亚洲一区二区三区在线播放|