在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

FMOD Antibody, HRP conjugated

  • 中文名稱:
    FMOD兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA008755LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) FMOD Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    FMOD
  • 別名:
    Collagen binding 59 kDa protein antibody; Collagen-binding 59 kDa protein antibody; Fibromodulin antibody; Fibromodulin precursor antibody; Fibromodulin proteoglycan antibody; FM antibody; FMOD antibody; FMOD_HUMAN antibody; Keratan sulfate proteoglycan fibromodulin antibody; KSPG fibromodulin antibody; SLRR2E antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Fibromodulin protein (18-89AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
  • 基因功能參考文獻:
    1. The results of luciferase reporter assay and methylation-specific PCR (MSP) demonstrated that GDNF facilitated the demethylation of the FMOD promoter. PMID: 30176167
    2. crystal structures at ~2.2A resolution of human fibromodulin and chondroadherin. PMID: 28215822
    3. we found that secreted FMOD as an important regulator of glioma cell migration downstream of TGF-beta1 pathway and forms a potential basis for therapeutic intervention in GBM. PMID: 27212030
    4. The small leucine rich proteoglycan fibromodulin is overexpressed in human prostate epithelial cancer cell lines in culture and human prostate cancer tissue. PMID: 26600400
    5. expression levels distinguish chronic lymphocytic leukemia B cells from normal B lymphocytes PMID: 26318878
    6. The data suggest a fibromodulin-modulated collagen cross-linking mechanism where fibromodulin binds to a specific part of the collagen domain and also forms a complex with lysyl oxidase, targeting the enzyme toward specific cross-linking sites. PMID: 26893379
    7. fibromodulin is involved in the inflammatory processes that characterize atherosclerotic plaque vulnerability PMID: 26125412
    8. The results suggest that regions within FMOD is associated with ACL injury susceptibility and that genetic sequence variability within genes encoding proteoglycans may potentially modulate the ligament fibril properties. PMID: 24552666
    9. Melanocyte-secreted factor FMOD is a key regulator of angiogenesis. PMID: 24355922
    10. Associations between higher fibomodulin gene expression and risk factors in chronic lymphocytic leukemia. PMID: 22099931
    11. Hepatic fibromodulin activates hepatic stellate cells and promotes collagen I deposition, which leads to liver fibrosis. PMID: 22138190
    12. lumican and fibromodulin display different behaviors and that lumican may promote regeneration of the TMJ after degeneration and deformation induced by IL-1 beta. PMID: 22073367
    13. study shows (1) a detailed description of ectopic ossification (EO) formed by Bgn, Fmod or combined depletion, (2) the role of exercise in modulating EO and (3) that Bgn and Fmod are critical in controlling motor function. PMID: 19422643
    14. Fibromodulin is shown for the first time to be naturally processed and presented as a tumor-associated antigen in primary chronic lymphocytic leukemia cells, enabling the expansion of autologous tumor-specific T cells. PMID: 15471955
    15. Fibromodulin has a role in progression of B-cell chronic lymphocytic leukemia and mantle cell lymphoma PMID: 15741214
    16. fibromodulin activates the classical pathway of complement by directly binding C1q PMID: 16046396
    17. complement control protein 6-8 is able to interact with DNA and necrotic cells, but in contrast the His-384 allotype binds these ligands more strongly than the Tyr-384 variant PMID: 17293598
    18. The collagen-binding Glu-353 and Lys-355 residues in fibromodulin are exposed on the exterior of the beta-sheet-loop structure of the leucine-rich repeat, which resembles the location of interacting residues in other leucine-rich repeat proteins. PMID: 17623650
    19. Fibromodulin gene is constantly expressed in human epidermal keratinocytes. PMID: 18448071
    20. Specific decorin and fibromodulin core protein fragments in degenerate meniscus and/or human articular cartilage may be of value as biomarkers of disease. PMID: 18620607
    21. CD200 blockade was further shown to stimulate antigen-specific T cell responses towards the CLL-associated antigen fibromodulin PMID: 18838168
    22. Homologous sequence in lumican and fibromodulin leucine-rich repeat 5-7 competes for collagen binding. PMID: 19008226
    23. Ultraviolet B and A irradiation induce FMOD expression in fibroblasts in vitro. PMID: 19041686
    24. differentially expressed in mesenchymal stromal cell subset with reduced differentiation potential PMID: 19242838
    25. tyrosine sulfate-rich domains of the LRR proteins fibromodulin and osteoadherin bind motifs of basic clusters in a variety of heparin-binding proteins, including bioactive factors PMID: 19700767

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族:
    Small leucine-rich proteoglycan (SLRP) family, SLRP class II subfamily
  • 數據庫鏈接:

    HGNC: 3774

    OMIM: 600245

    KEGG: hsa:2331

    STRING: 9606.ENSP00000347041

    UniGene: Hs.519168



主站蜘蛛池模板: 天天爽夜夜爱| 看曰本女人大战黑人视频| 国产成人无码网站| 欧美丰满少妇xxxx性| 中文字幕乱码人在线视频1区| 国色天香天天影院综合网 | 色欲天天婬色婬香综合网完整版| 久久精品人人槡人妻人人玩av| 国产精品久久久久久久伊一| 综合亚洲桃色第一影院| 国产无遮挡吃胸膜奶免费看| 久久久久无码精品亚洲日韩| 国产精品有码无码av在线播放 | 国产成年女人特黄特色毛片免| 国产尤物精品自在拍视频首页| 欧美成人片一区二区三区| 国产在线观看码高清视频| 亚洲最大成人综合网720p| 天天综合色天天综合色h| 人人爽人人澡人人人妻、百度| 少妇粗大进出白浆嘿嘿视频| 午夜福利一区二区三区在线观看| 污18禁污色黄网站免费| 免费人成激情视频在线观看| 国产精品久久久久影院亚瑟| 极品少妇xxxx精品少妇偷拍| 波多野结衣的av一区二区三区| 中国女人大白屁股ass| 人妻熟女一区二区aⅴ水野朝阳| 九九视频免费精品视频| 国产无套精品一区二区三区| 亚洲 中文 欧美 日韩 在线| 国产精品国语对白露脸在线播放| 99久久99视频只有精品| 亚洲精品黑牛一区二区三区| 特黄大片又粗又大又暴| 国产精品多p对白交换绿帽| 国产成人av片无码免费| 日韩v亚洲v欧美v精品综合| 欧美深度肠交惨叫| 男女野外做爰全过程69影院|