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  4. FGFR1OP2 Antibody

FGFR1OP2 Antibody

  • 中文名稱：
    FGFR1OP2兔多克隆抗體
  • 貨號：
    CSB-PA070949
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA070949(FGFR1OP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA070949(FGFR1OP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    FGFR1OP2
  • 別名：
    DKFZp564O1863 antibody; FGFR1 oncogene partner 2 antibody; FGFR1OP2 antibody; FGOP2_HUMAN antibody; Fibroblast growth factor receptor 1 oncogene partner 2 antibody; HSPC123 antibody; HSPC123 like antibody; WIT3.0 antibody; Wound inducible transcript 3.0 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human FGFR1OP2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May be involved in wound healing pathway.
  • 基因功能參考文獻：
    1. The patient with minor allele of ss518063493 may be associated with excessive atrophy of edentulous mandible whereas the patients with that of rs840869 are not associated in Korean population. PMID: 22880093
    2. patients with the minor allele of rs840869 or rs859024 of FGFR1OP2 were associated with excessive atrophy of edentulous mandible PMID: 21283824
    3. FGFR1OP2/wit3.0 may regulate cell motility and stimulate wound closure. PMID: 19959814
    4. FGFR1OP2 is a new FGFR1 fusion gene involving a chromosomes 12X8 translocation in a 8p11 myeloproliferative syndrome patient. PMID: 15034873
  • 相關疾病：
    A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    SIKE family
  • 組織特異性：
    Expressed in bone marrow, spleen and thymus.
  • 數據庫鏈接：

    HGNC: 23098

    OMIM: 608858

    KEGG: hsa:26127

    STRING: 9606.ENSP00000229395

    UniGene: Hs.591162



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