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FEN1 Antibody, Biotin conjugated

Rare Species
  • 中文名稱:
    FEN1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA008585LD01DOA
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) FEN1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    FEN1 antibody; At5g26680 antibody; F21E10.3Flap endonuclease 1 antibody; FEN-1 antibody; EC 3.1.-.- antibody; Flap structure-specific endonuclease 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Arabidopsis thaliana
  • 免疫原:
    Recombinant Arabidopsis thaliana Flap endonuclease 1 protein (85-383AA)
  • 免疫原種屬:
    Arabidopsis thaliana (Mouse-ear cress)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
  • 基因功能參考文獻:
    1. At5g26680 role in mediating transcriptional gene silencing as well as maintaining genome stability PMID: 27231839
    2. Data show that shade avoidance 6 (SAV6; At5g26680), encodes flap endonuclease-1 (FEN1), assures proper root development through maintenance of genome integrity. PMID: 26721386
  • 亞細胞定位:
    Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion.
  • 蛋白家族:
    XPG/RAD2 endonuclease family, FEN1 subfamily
  • 數據庫鏈接:

    KEGG: ath:AT5G26680

    STRING: 3702.AT5G26680.1

    UniGene: At.47103



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