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FBXW10 Antibody

  • 中文名稱:
    FBXW10兔多克隆抗體
  • 貨號:
    CSB-PA726395LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA726395LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA726395LA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) FBXW10 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    FBXW10
  • 別名:
    FBXW10 antibody; F-box/WD repeat-containing protein 10 antibody; F-box and WD-40 domain-containing protein 10 antibody; Ubiquitin ligase-specificity factor antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human F-box/WD repeat-containing protein 10 protein (701-1000AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,FBXW10 Antibody (CSB-PA726395LA01HU),的標記方式是Non-conjugated。對于FBXW10 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA726395LB01HU FBXW10 Antibody, HRP conjugated ELISA
    FITC CSB-PA726395LC01HU FBXW10 Antibody, FITC conjugated
    Biotin CSB-PA726395LD01HU FBXW10 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Probable substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1.
  • 基因功能參考文獻:
    1. O-GlcNAcylation is involved in the regulation of ubiquitination-related genes including FBXW10 PMID: 23899520
    2. Mislocalized lamins can induce ubiquitin-mediated proteasomal degradation of certain HP1 isoforms by activation of FBXW10, a member of the F-box family of proteins that is involved in E3 ubiquitin ligase activity. PMID: 20498703
  • 數據庫鏈接:

    HGNC: 1211

    OMIM: 611679

    KEGG: hsa:10517

    STRING: 9606.ENSP00000379026

    UniGene: Hs.592128



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