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FBXW10 Antibody, Biotin conjugated

  • 中文名稱:
    FBXW10兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào):
    CSB-PA726395LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) FBXW10 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    FBXW10
  • 別名:
    FBXW10 antibody; F-box/WD repeat-containing protein 10 antibody; F-box and WD-40 domain-containing protein 10 antibody; Ubiquitin ligase-specificity factor antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human F-box/WD repeat-containing protein 10 protein (701-1000AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Probable substrate-recognition component of a SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Overexpression is leading to degradation of CBX5 and CBX1.
  • 基因功能參考文獻(xiàn):
    1. O-GlcNAcylation is involved in the regulation of ubiquitination-related genes including FBXW10 PMID: 23899520
    2. Mislocalized lamins can induce ubiquitin-mediated proteasomal degradation of certain HP1 isoforms by activation of FBXW10, a member of the F-box family of proteins that is involved in E3 ubiquitin ligase activity. PMID: 20498703
  • 數(shù)據(jù)庫鏈接:

    HGNC: 1211

    OMIM: 611679

    KEGG: hsa:10517

    STRING: 9606.ENSP00000379026

    UniGene: Hs.592128



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