在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. FBXO25 Antibody, HRP conjugated

FBXO25 Antibody, HRP conjugated

  • 中文名稱：
    FBXO25兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA848401LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) FBXO25 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    F box only protein 25 antibody; F box protein 25 antibody; F box protein Fbx25 antibody; F-box only protein 25 antibody; FBX25 antibody; FBX25_HUMAN antibody; FBXO25 antibody; MGC20256 antibody; MGC51975 antibody; OTTHUMP00000115399 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human F-box only protein 25 protein (1-291AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT).
  • 基因功能參考文獻：
    1. Taken together we show that FBXO25 functions as a negative regulator of MAPK signaling though the reduction of ERK1/2 activation. PMID: 28389297
    2. High FBXO25 expression is associated with non-small-cell lung cancer. PMID: 27596142
    3. FBXO25 functions as a haploinsufficient tumor suppressor in mantle cell lymphoma. PMID: 25419709
    4. FBXO25 mediates ELK-1 degradation through the ubiquitin proteasome system and thereby plays a role in regulating the activation of ELK-1 pathway in response to mitogens PMID: 23940030
    5. Altogether, Fbxo25 acts as an ubiquitin E3 ligase to target cardiac transcription factors including Nkx2-5, Isl1, and Hand1, indicating that cardiac protein homeostasis through Fbxo25 has a pivotal impact on cardiac development. PMID: 21596019
    6. Beta-actin, physically interacts through its N-terminus with FBXO25 and is enriched in the FBXO25 nuclear compartments. PMID: 20473970
    7. investigated hFBX25's genomic organization and established hFBX25 as an FBP by verifying its interaction with Skp1 and Cul1 PMID: 16278047
    8. The cellular distribution of FBXO25 and its colocalization with some nuclear proteins is investigated by using immunochemical and biochemical approaches. PMID: 18287534

    顯示更多

    收起更多

  • 相關疾?。?/div>
    A chromosomal aberration involving FBXO25 is a cause of X-linked mental retardation (XLMR). Translocation t(X;8)(p11.22;p23.3) with SHROOM4.
  • 亞細胞定位：
    Nucleus. Note=In the nucleus, associates with a subnuclear dot-like structure. Colocalized with SKP1.
  • 組織特異性：
    Expressed in all brain tissue observed.
  • 數據庫鏈接：

    HGNC: 13596

    OMIM: 609098

    KEGG: hsa:26260

    STRING: 9606.ENSP00000276326

    UniGene: Hs.438454



主站蜘蛛池模板： 国产一码二码三码区别| 国产熟妇搡bbbb搡bbbb| 亚洲欧美精品aaaaaa片| 国产精品www夜色视频| 浮妇高潮喷白浆视频| 精品亚洲国产成人av在线时间短的 | 无码人妻精品一区二| 人妻熟女一区二区aⅴ图片| 国产精品aⅴ在线观看| 国产办公室秘书无码精品99| 欧美多毛肥胖老妇做爰| 亚洲欧美日韩成人高清在线一区| 亚洲中文字幕精品久久| 边啃奶头边躁狠狠躁玩爽在水里面| 国语自产偷拍精品视频蜜芽 | 亚洲第一无码xxxxxx| 欧美巨大另类极品videosbest| 国产精品亚洲一区二区无码| 青草青在线视频在线观看| 产后漂亮奶水人妻无码| 亚洲日韩av无码| 日本被黑人强伦姧人妻完整版| 大学生久久香蕉国产线看观看| 97人妻免费碰视频碰免| 国产尤物在线视精品在亚洲| 丰满少妇熟乱xxxxx视频| 精品欧洲av无码一区二区三区 | 日本成a人片在线播放| 久久久久免费精品国产| 人妻少妇精品中文字幕av | av无码午夜福利一区二区三区| 国产aⅴ夜夜欢一区二区三区| 风韵少妇性饥渴推油按摩视频| 国产精品国产三级国产aⅴ下载| 永久免费观看黄网视频| 日本真人边吃奶边做爽电影| 永久免费无码网站在线观看| 亚洲精品久久久www| 国产7色在线 | 国产| 欲色欲色天天天www| 久久99国产综合精品|