在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. FAM107A Antibody

FAM107A Antibody

  • 中文名稱：
    FAM107A兔多克隆抗體
  • 貨號：
    CSB-PA007987LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA007987LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) FAM107A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    FAM107A
  • 別名：
    Down regulated in renal cell carcinoma 1 antibody; Down-regulated in renal cell carcinoma 1 antibody; Downregulated in renal cell carcinoma antibody; DRR1 antibody; F107A_HUMAN antibody; FAM107A antibody; Family with sequence similarity 107; member A antibody; FLJ30158 antibody; FLJ45473 antibody; Protein FAM107A antibody; Protein TU3A antibody; TU3A antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Actin-associated protein FAM107A protein (1-144AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，FAM107A Antibody (CSB-PA007987LA01HU)，的標記方式是Non-conjugated。對于FAM107A Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA007987LB01HU FAM107A Antibody, HRP conjugated ELISA
    FITC CSB-PA007987LC01HU FAM107A Antibody, FITC conjugated
    Biotin CSB-PA007987LD01HU FAM107A Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin) dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory. Plays a role in the actin and microtubule cytoskeleton organization; negatively regulates focal adhesion (FA) assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner. Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner. May play a role in tumor development.
  • 基因功能參考文獻：
    1. This study has thus revealed a novel nuclear complex of F-actin, DRR1 and COMMD1 that is involved in NF-kappaB degradation and cell cycle suppression in neuroblastoma cells. PMID: 28604741
    2. Importance of FAM107A in lung carcinogenesis, although other than promoter hypermethylation mechanism of the gene decreased expression. PMID: 25753555
    3. Results found that DRR expression leads to elevated AKT activation by recruiting AKT to focal adhesios in a manner dependent on SRC-family kinases (SFKs) and cell adhesion. PMID: 24141773
    4. DRR1 protein is expressed in normal cells, particularly in the nervous system during embryogenesis, is involved in neuronal cell survival, and is downregulated during neuroblastoma carcinogenesis. PMID: 20298674
    5. Expression of the down-regulated in renal cell carcinoma gene (DRR1) gene at 3p14.2 was lost in 7 and down regulated in 2 "chr3+" tumours. PMID: 16432833
    6. TU3A is epigenetically inactivated in human cancer PMID: 18813805

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm, cytoskeleton, stress fiber. Cell junction, focal adhesion. Cell projection, ruffle membrane. Cell junction, synapse.
  • 蛋白家族：
    FAM107 family
  • 組織特異性：
    Widely expressed. Expressed in neurons. Expressed in malignant glial tumors. Expression is reduced or absent in a number of cancer cell lines.
  • 數據庫鏈接：

    HGNC: 30827

    OMIM: 608295

    KEGG: hsa:11170

    STRING: 9606.ENSP00000354270

    UniGene: Hs.506357



主站蜘蛛池模板： 精品人妻中文字幕有码在线| 精品人妻二区中文字幕| 国产成人精品视频ⅴa片软件竹菊 免费精品99久久国产综合精品 | 午夜寂寞少妇aaa片毛片| 后进式无遮挡啪啪摇乳动态图| 蜜臀av色欲a片无码一区| 中文字幕亚洲码在线观看| 大陆熟妇丰满多毛xxxx| 97影院在线午夜| 日本欧美亚洲中文在线观看| 亚洲精品v日韩精品| 综合无码一区二区三区| 国内大量揄拍人妻在线视频| 亚洲欧美v国产一区二区| 欧美va亚洲va在线观看日本| 无码任你躁久久久久久老妇蜜桃| 亚洲蜜芽在线精品一区| 国产9色在线 | 日韩| 成人伊人亚洲人综合网站| 天堂中文资源库官网| 巨大欧美黑人xxxxbbbb| 天天弄天天模| 一个色综合国产色综合| 成人无遮挡裸免费视频在线观看| 麻豆av一区二区三区| 国产69精品久久久久app下载| 亚洲精品无码久久毛片波多野吉衣| 综合亚洲桃色第一影院| 欧美自拍嘿咻内射在线观看| a毛看片免费观看视频| 玩弄人妻少妇老师美妇厨房| 欧美三根一起进三p| 久久精品人人槡人妻人| 尤物蜜芽国产成人精品区| 国产精品国产三级国快看| 精品国内自产拍在线观看视频| 无码av免费一区二区三区四区| 国产老熟妇精品观看| 熟妇丰满多毛的大隂户| 天堂va欧美va亚洲va好看va| 一区二区三区无码免费看|