在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. FAM107A Antibody

FAM107A Antibody

  • 中文名稱：
    FAM107A兔多克隆抗體
  • 貨號：
    CSB-PA775661
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA775661(FAM107A Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA775661(FAM107A Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    FAM107A
  • 別名：
    Down regulated in renal cell carcinoma 1 antibody; Down-regulated in renal cell carcinoma 1 antibody; Downregulated in renal cell carcinoma antibody; DRR1 antibody; F107A_HUMAN antibody; FAM107A antibody; Family with sequence similarity 107; member A antibody; FLJ30158 antibody; FLJ45473 antibody; Protein FAM107A antibody; Protein TU3A antibody; TU3A antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Fusion protein of Human FAM107A
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin) dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory. Plays a role in the actin and microtubule cytoskeleton organization; negatively regulates focal adhesion (FA) assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner. Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner. May play a role in tumor development.
  • 基因功能參考文獻：
    1. This study has thus revealed a novel nuclear complex of F-actin, DRR1 and COMMD1 that is involved in NF-kappaB degradation and cell cycle suppression in neuroblastoma cells. PMID: 28604741
    2. Importance of FAM107A in lung carcinogenesis, although other than promoter hypermethylation mechanism of the gene decreased expression. PMID: 25753555
    3. Results found that DRR expression leads to elevated AKT activation by recruiting AKT to focal adhesios in a manner dependent on SRC-family kinases (SFKs) and cell adhesion. PMID: 24141773
    4. DRR1 protein is expressed in normal cells, particularly in the nervous system during embryogenesis, is involved in neuronal cell survival, and is downregulated during neuroblastoma carcinogenesis. PMID: 20298674
    5. Expression of the down-regulated in renal cell carcinoma gene (DRR1) gene at 3p14.2 was lost in 7 and down regulated in 2 "chr3+" tumours. PMID: 16432833
    6. TU3A is epigenetically inactivated in human cancer PMID: 18813805

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm, cytoskeleton, stress fiber. Cell junction, focal adhesion. Cell projection, ruffle membrane. Cell junction, synapse.
  • 蛋白家族：
    FAM107 family
  • 組織特異性：
    Widely expressed. Expressed in neurons. Expressed in malignant glial tumors. Expression is reduced or absent in a number of cancer cell lines.
  • 數據庫鏈接：

    HGNC: 30827

    OMIM: 608295

    KEGG: hsa:11170

    STRING: 9606.ENSP00000354270

    UniGene: Hs.506357



主站蜘蛛池模板： 国产亚洲熟妇综合视频| 男人撕开奶罩揉吮奶头视频| 日韩精品一区二区av在线观看| 麻豆国产原创视频在线播放| 国产乱人伦真实精品视频| 久久99热人妻偷产国产| 久久亚洲精品无码播放| 国产一卡2卡3卡四卡精品国色无边 | 国内偷自第一区二区三区| 韩国午夜福利片在线| 精品国产va久久久久久久冰| 中年熟妇的大黑p| 超清无码av最大网站| 麻豆精品偷拍人妻在线网址| 欧美mv日韩mv国产网站| 久久综合狠狠色综合伊人| 玩弄了裸睡少妇人妻野战| 奇米影视7777狠狠狠狠影视| 亚洲国产中文字幕在线视频综合| 24小时日本在线www免费的| 人妻少妇无码精品专区| 人妻无码久久一区二区三区免费| 欧洲熟妇色xxxxx欧美老妇伦| 99精品热这里只有精品| 欧美性受xxxxzooz乱毛| 日本精品人妻无码77777| 在线人人车操人人看视频| 日日碰狠狠添天天爽超碰97| 少妇被躁爽到高潮无码人狍大战| 高潮添下面视频免费看| 日产精品卡1卡2卡三卡在线| 亚洲国产精品久久久久秋霞小说| 天天狠天天透天天伊人| 国产精品无码成人午夜电影| 欧洲 亚洲 国产图片综合| 欧美xxxx做受视频| 波多野结衣av手机在线观看| 人人妻人人澡人人爽人人精品97| 东京热无码国产精品| 亚洲第一aaaaa片| 麻豆国产在线精品国偷产拍|