在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. FABP6 Antibody

FABP6 Antibody

  • 中文名稱：
    FABP6兔多克隆抗體
  • 貨號：
    CSB-PA170264
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA170264(FABP6 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA170264(FABP6 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Fabp6 antibody; FABP6_HUMAN antibody; Fatty acid binding protein 6; ileal (gastrotropin) antibody; Fatty acid-binding protein 6 antibody; Gastrotropin antibody; GT antibody; I 15P antibody; I BABP antibody; I BALB antibody; I BAP antibody; I-15P antibody; I-BABP antibody; I15P antibody; IBABP antibody; IBALB antibody; IBAP antibody; ILBP antibody; ILBP3 antibody; Ileal lipid binding protein antibody; Ileal lipid-binding protein antibody; ILLBP antibody; Intestinal 15 kDa protein antibody; Intestinal bile acid binding protein antibody; Intestinal bile acid-binding protein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Fusion protein of Human FABP6
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes. In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion.; Essential for the survival of colon cancer cells to bile acid-induced apoptosis.
  • 基因功能參考文獻：
    1. Structural determinants of ligand binding in the ternary complex of human ileal bile acid binding protein with glycocholate and glycochenodeoxycholate obtained from solution NMR PMID: 26613247
    2. Analysis of slow and fast motions in I-BABP indicates largely different energy landscapes for the apo and holo states suggesting that optimization of binding interactions might be achieved by altering the dynamic behavior of specific protein segments. PMID: 25073073
    3. show, using electrospray ionization mass spectroscopy, that human ILBP binds bile acids with a 3:1 ratio, even at low protein and ligand concentrations PMID: 23758264
    4. Ursodeoxycholic acid induces unique conformational changes in IBABP. PMID: 22223860
    5. NMR data are in agreement with a conformational selection model we proposed earlier for I-BABP and support the hypothesis of an allosteric mechanism of ligand binding PMID: 22329738
    6. The-putative functional-Thr79Met substitution of FABP6 confers a protective effect on type 2 diabetes in obese individuals. PMID: 19744871
    7. NMR structure of human ileal lipid-binding protein-cholyltaurine complex and its comparison with homologous structures PMID: 12486725
    8. the I-BABP gene may be a novel target for PPAR in humans PMID: 15936983
    9. ASBT and ILBP protein were 48% and 67% lower in normal weight gallstone carriers than in controls (P < 0.05); similar differences were found for mRNA expression levels. PMID: 16237211
    10. The expression of FABP6 was higher in primary colorectal cancers and adenomas than in normal epithelium, but was dramatically decreased in lymph node metastases, suggesting that FABP6 may play an important role in early carcinogenesis. PMID: 16951225
    11. In keeping with its role in the enterohepatic circulation and ileal reabsorption of bile acids, the gene promoter contains consensus elements for CDX2 and FXR. More than one transcription start site has been identified. PMID: 14654244

    顯示更多

    收起更多

  • 亞細胞定位：
    [Isoform 1]: Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side.; [Isoform 2]: Cytoplasm.
  • 蛋白家族：
    Calycin superfamily, Fatty-acid binding protein (FABP) family
  • 組織特異性：
    Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is xpressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. Isoform 2 is expressed in c
  • 數據庫鏈接：

    HGNC: 3561

    OMIM: 600422

    KEGG: hsa:2172

    STRING: 9606.ENSP00000377549

    UniGene: Hs.519719



主站蜘蛛池模板： 久久国产精品2020免费| 无码精品人妻一区二区三区人妻斩| 中文无码字幕中文有码字幕| 99精品久久久久中文字幕| 久久ww精品w免费人成| 熟女人妻大叫粗大受不了| 久久99精品国产麻豆蜜芽| 久久综合狠狠综合久久综| 亚洲国产精品无码中文字2022| 西欧free性满足hd老熟妇| 日本高清视频www| 国产成人美女裸体片免费看| 在线中文字幕亚洲日韩2020| 99久久国产热无码精品免费| 亚洲欧美中文日韩v日本| 亚洲国产精品无码久久一区二区| 久久天天躁夜夜躁狠狠85台湾| 日产精品卡2卡三卡乱码网址| 亚洲精品无码国产片| 国产真实夫妇交换视频| 日韩人妻无码精品系列专区| 亚洲成av人在线观看网站| 任你躁x7x7x7x7在线观看| 亚洲欧美中文日韩在线视频一| 国产男女猛烈视频在线观看| 开心婷婷五月激情综合社区| 日本高清在线一区二区三区 | 亚洲欧洲∨国产一区二区三区| 无码午夜福利视频1000集| 午夜福利理论片高清在线观看 | 精品乱人伦一区二区三区| 熟妇人妻久久中文字幕| 亚洲国产成人久久久网站| av在线 亚洲 天堂| 狠狠躁夜夜躁人人爽天天5| 丰满护士巨好爽好大乳| 亚洲精品午夜久久久伊人| 免费无遮挡无码永久在线观看视频 | 精品人妻少妇一区二区三区不卡 | 欧美饥渴熟妇高潮喷水| 色婷婷亚洲一区二区综合|