在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EXOSC1 Antibody, HRP conjugated

  • 中文名稱:
    EXOSC1兔多克隆抗體, HRP偶聯(lián)
  • 貨號:
    CSB-PA897103LB01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) EXOSC1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    EXOSC1
  • 別名:
    3'-5' exoribonuclease CSL4 homolog antibody; CGI 108 antibody; CGI-108 antibody; CSL4 antibody; CSL4 exosomal core protein homolog antibody; CSL4, S. cerevisiae, homolog of antibody; Csl4p antibody; EXOS1_HUMAN antibody; Exosc1 antibody; Exosomal core protein CSL4 antibody; Exosome complex component csl4 antibody; Exosome component 1 antibody; hCsl4p antibody; Homolog of yeast exosomal core protein CSL4 antibody; p13 antibody; RP11-452K12.9 antibody; SKI4 antibody; Ski4p antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Exosome complex component CSL4 protein (9-195AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC1 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC6 and EXOSC8.
  • 基因功能參考文獻(xiàn):
    1. The combined p16- and p53-expression status in cervical metastases of CUP may represent a simple method for risk stratification. Further validation of these biomarkers in large prospective trials is essential to design rational trials for CUP treatment optimization. PMID: 28144684
    2. Human exosome hCsl4p participates in RNA degradation. PMID: 22068837
    3. association of hCsl4p with the exosome is mediated by protein-protein interactions with hRrp42p and hRrp46p PMID: 11812149
  • 亞細(xì)胞定位:
    Nucleus, nucleolus. Nucleus. Cytoplasm.
  • 蛋白家族:
    CSL4 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 17286

    OMIM: 606493

    KEGG: hsa:51013

    STRING: 9606.ENSP00000359939

    UniGene: Hs.632089



主站蜘蛛池模板: 午夜男女爽爽影院免费视频下载| 欧美成人午夜免费影院手机在线看| 精品国产一区二区三区无码| 国产亚洲精品a在线无码| 成人看的污污超级黄网站免费| 国产永久免费观看的黄网站| 亚洲人成电影网站在线观看| 国产乱人偷精品人妻a片| 人人鲁人人莫人人爱精品| 日本一区二区无卡高清视频| av无码欧洲亚洲电影网| 老太脱裤让老头玩ⅹxxxx| 成人国产三级在线观看| 国产欧色美视频综合二区| 少妇群交换bd高清国语版| 射死你天天日| 中文字幕熟妇人妻在线视频| 久久久久久亚洲精品a片成人| 无码任你躁久久久久久| 国产精品熟妇视频国产偷人| 亚洲色婷婷婷婷五月基地| 无码人妻一区二区三区四区av| 亚洲色大成网站www永久| 亚洲性无码av中文字幕| 巨熟乳波霸若妻在线播放| 五月丁香综合激情六月久久 | 天天做av天天爱天天爽| 久久97超碰色中文字幕蜜芽| av免费网址在线观看| 久久精品国产精品亚洲下载| 狼友网精品视频在线观看| 亚洲大尺度无码专区尤物 | 国产边摸边吃奶边做爽视频| 成人夜色视频网站在线观看| 51国产偷自视频区视频| 99精品国产一区二区三区| 成人毛片av免费| 嫩草伊人久久精品少妇av| 和岳每晚弄的高潮嗷嗷叫视频| 137裸交肉体摄影| 国产卡一卡二无线乱码|