在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

EXOSC1 Antibody, Biotin conjugated

  • 中文名稱:
    EXOSC1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA897103LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) EXOSC1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    EXOSC1
  • 別名:
    3'-5' exoribonuclease CSL4 homolog antibody; CGI 108 antibody; CGI-108 antibody; CSL4 antibody; CSL4 exosomal core protein homolog antibody; CSL4, S. cerevisiae, homolog of antibody; Csl4p antibody; EXOS1_HUMAN antibody; Exosc1 antibody; Exosomal core protein CSL4 antibody; Exosome complex component csl4 antibody; Exosome component 1 antibody; hCsl4p antibody; Homolog of yeast exosomal core protein CSL4 antibody; p13 antibody; RP11-452K12.9 antibody; SKI4 antibody; Ski4p antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Exosome complex component CSL4 protein (9-195AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC1 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC6 and EXOSC8.
  • 基因功能參考文獻:
    1. The combined p16- and p53-expression status in cervical metastases of CUP may represent a simple method for risk stratification. Further validation of these biomarkers in large prospective trials is essential to design rational trials for CUP treatment optimization. PMID: 28144684
    2. Human exosome hCsl4p participates in RNA degradation. PMID: 22068837
    3. association of hCsl4p with the exosome is mediated by protein-protein interactions with hRrp42p and hRrp46p PMID: 11812149
  • 亞細胞定位:
    Nucleus, nucleolus. Nucleus. Cytoplasm.
  • 蛋白家族:
    CSL4 family
  • 數據庫鏈接:

    HGNC: 17286

    OMIM: 606493

    KEGG: hsa:51013

    STRING: 9606.ENSP00000359939

    UniGene: Hs.632089



主站蜘蛛池模板: 国产av无码专区亚洲版综合| 夜夜欢性恔免费视频| 国产成 人 综合 亚洲网站| 欧美又黄又大又爽a片三年片| 色窝窝无码一区二区三区色欲| 欧美叉叉叉bbb网站| 国产综合有码无码视频在线| 亚洲.日韩.欧美另类| 亚洲区小说区图片区qvod| 天天做天天爱夜夜爽| 亚洲性啪啪无码av天堂| av无码精品一区二区三区宅噜噜| 真人性生交免费视频| 国色天香国产精品| 国产一卡二卡三卡四卡视频版| 99精品欧美一区二区三区| 黑人大战亚洲人精品一区| 无码国产玉足脚交极品播放| 久久精品国产清高在天天线| 国产精品久久国产三级国不卡顿| 久久精品无码一区二区日韩av| 狠狠狠色丁香综合婷婷久久| 亚洲精品中文字幕| 中文字幕无线码一区二区| 亚洲人成网亚洲欧洲无码久久| 国产午夜草莓视频在线观看| 精品国产第一国产综合精品| 伊人色综合久久天天小片| 少妇和邻居做不戴套视频| 免费观看成人欧美www色| 97人妻人人揉人人躁人人| 久激情内射婷内射蜜桃人妖 | 校花高潮抽搐冒白浆| 毛片免费视频观看| 国产精品无码av天天爽| 被窝影院午夜无码国产| 疯狂三人交性欧美| 欧美国产国产综合视频| 精品国精品国产自在久国产不卡| 国产精品成人99久久久久| 色婷婷亚洲一区二区三区|