在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ETFB Antibody

  • 中文名稱:
    ETFB兔多克隆抗體
  • 貨號:
    CSB-PA007845GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    ETFB
  • 別名:
    Beta ETF antibody; Beta-ETF antibody; Electron transfer flavoprotein beta polypeptide antibody; Electron transfer flavoprotein beta subunit antibody; Electron transfer flavoprotein subunit beta antibody; Electron transferring flavoprotein beta polypeptide antibody; etfB antibody; ETFB_HUMAN antibody; FP585 antibody; MADD antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human ETFB
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (Probable). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. ETFB binds an AMP molecule that probably has a purely structural role.
  • 基因功能參考文獻:
    1. We identified and replicated a novel gene, ETFB, strongly associated with chronic anthracycline-induced cardiotoxicity independently of age at tumor onset and related to anthracycline-mediated mitochondrial dysfunction PMID: 28913729
    2. These results suggested that increasing levels of ATP5B and ETFB were associated with worsening renal injury. PMID: 27840937
    3. the findings of our present study suggest that ETFbeta plays an important role in renal tubular cell apoptosis during the progression of DN. PMID: 27035869
    4. Electron Transfer Flavoprotein Subunit Beta Is a Candidate Endothelial Cell Autoantigen in Behcet's Disease PMID: 25915519
    5. Human METTL20 is a mitochondrial lysine methyltransferase that targets ETFbeta and modulates its activity. PMID: 25416781
    6. ETFB knockdown can affect TGF-beta-induced tissue remodeling and/or fibrotic processes in vitro. PMID: 23068445
    7. Point mutations in electron-transfer-flavoprotein beta is associated with destabilized conformations and defective protein:protein interactions leading to mitochondrial dysfunction. PMID: 22588007
    8. ETFB participates in the mechanoregulation of fibroblast cell number in collagen gel culture. PMID: 21903359
    9. non-productive conformation stabilization underpins rapid electron transfer to electron-transferring flavoprotein PMID: 15975918
    10. Tissue samples from 16 unrelated patients with ETF deficiency were analysed, two of them harboured mutations in the ETFB gene. PMID: 16510302
    11. conformational and stability properties of the disease-causing variant ETFbeta-D128N, and our findings on the effect of flavinylation in modulating protein conformational stability and activity. PMID: 19088074

    顯示更多

    收起更多

  • 相關疾病:
    Glutaric aciduria 2B (GA2B)
  • 亞細胞定位:
    Mitochondrion matrix.
  • 蛋白家族:
    ETF beta-subunit/FixA family
  • 組織特異性:
    Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas.
  • 數據庫鏈接:

    HGNC: 3482

    OMIM: 130410

    KEGG: hsa:2109

    STRING: 9606.ENSP00000346173

    UniGene: Hs.348531



主站蜘蛛池模板: 天堂va欧美ⅴa亚洲va在线| 国产国拍精品av在线观看| 奇米在线7777在线精品| 国产老熟女狂叫对白| 亚洲丰满熟女一区二区v| 蜜桃视频网站| 巨胸喷奶水视频www免费网站| 久久亚洲精品人成综合网| 欧美精品一区二区黄a片| 国产伦精品一区二区三区免费迷| 日韩无套内射视频6| 97se亚洲精品一区二区| 在线观看肉片av网站免费| 高h纯肉无码视频在线观看| 国产成人乱色伦区| 久久一卡二卡三卡四卡| 亚洲中文字幕无码永久在线 | 国产丝袜美女| 日韩毛片在线视频x| 欧美不卡无线在线一二三区观| 国产亚洲精品自在久久vr| a亚洲va欧美va国产综合| 色综合久久久久综合体桃花网| 亚洲日韩日本中文在线| 久久精品手机观看| 亚洲国产精品成人无码区| 色欲色香天天天综合无码| 又色又爽又黄的美女裸体网站 | 国产玉足脚交极品在线播放| 无码人妻日韩一区日韩二区| 欧美精品黑人粗大视频| 人妻丰满熟妇av无码区hd| 亚洲中文字幕无码天然素人| 国产视频一区二区| 国产精品熟妇视频国产偷人| 亚洲综合精品第一页| 亚洲人成无码网www| 亚裔大战黑人老外av| 人人玩人人添人人澡| 久久国产精品_国产精品| 亚洲精品久久无码av片|