在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ETFB Antibody

  • 中文名稱:
    ETFB兔多克隆抗體
  • 貨號:
    CSB-PA007845GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    ETFB
  • 別名:
    Beta ETF antibody; Beta-ETF antibody; Electron transfer flavoprotein beta polypeptide antibody; Electron transfer flavoprotein beta subunit antibody; Electron transfer flavoprotein subunit beta antibody; Electron transferring flavoprotein beta polypeptide antibody; etfB antibody; ETFB_HUMAN antibody; FP585 antibody; MADD antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human ETFB
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (Probable). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. ETFB binds an AMP molecule that probably has a purely structural role.
  • 基因功能參考文獻:
    1. We identified and replicated a novel gene, ETFB, strongly associated with chronic anthracycline-induced cardiotoxicity independently of age at tumor onset and related to anthracycline-mediated mitochondrial dysfunction PMID: 28913729
    2. These results suggested that increasing levels of ATP5B and ETFB were associated with worsening renal injury. PMID: 27840937
    3. the findings of our present study suggest that ETFbeta plays an important role in renal tubular cell apoptosis during the progression of DN. PMID: 27035869
    4. Electron Transfer Flavoprotein Subunit Beta Is a Candidate Endothelial Cell Autoantigen in Behcet's Disease PMID: 25915519
    5. Human METTL20 is a mitochondrial lysine methyltransferase that targets ETFbeta and modulates its activity. PMID: 25416781
    6. ETFB knockdown can affect TGF-beta-induced tissue remodeling and/or fibrotic processes in vitro. PMID: 23068445
    7. Point mutations in electron-transfer-flavoprotein beta is associated with destabilized conformations and defective protein:protein interactions leading to mitochondrial dysfunction. PMID: 22588007
    8. ETFB participates in the mechanoregulation of fibroblast cell number in collagen gel culture. PMID: 21903359
    9. non-productive conformation stabilization underpins rapid electron transfer to electron-transferring flavoprotein PMID: 15975918
    10. Tissue samples from 16 unrelated patients with ETF deficiency were analysed, two of them harboured mutations in the ETFB gene. PMID: 16510302
    11. conformational and stability properties of the disease-causing variant ETFbeta-D128N, and our findings on the effect of flavinylation in modulating protein conformational stability and activity. PMID: 19088074

    顯示更多

    收起更多

  • 相關疾病:
    Glutaric aciduria 2B (GA2B)
  • 亞細胞定位:
    Mitochondrion matrix.
  • 蛋白家族:
    ETF beta-subunit/FixA family
  • 組織特異性:
    Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas.
  • 數據庫鏈接:

    HGNC: 3482

    OMIM: 130410

    KEGG: hsa:2109

    STRING: 9606.ENSP00000346173

    UniGene: Hs.348531



主站蜘蛛池模板: 亚洲成a∧人片在线播放调教| 国产97色在线 | 日韩| 成人综合婷婷国产精品久久 | 经典三级欧美在线播放| 夜夜欢天天干| 97精品久久久久中文字幕| 无码精品久久一区二区三区| 日产精品1区2区3区| 国产欧美日韩中文久久| 久久精品一区二区三区四区| 亚洲精品无码av黄瓜影视| 720lu国产刺激无码| 狠狠躁天天躁中文字幕无码| 久久国产精品偷| 免费无码av片在线观看潮喷| 成人无码一区二区三区网站| 成在线人视频免费视频| 一个人在线观看免费中文www| 国产免费啪嗒啪嗒视频看看| 亚洲精品国产一二三无码av| 亚瑟国产精品久久| 亚洲精品久久久www| 亚洲色在线无码国产精品| 欧美人伦禁忌dvd放荡欲情| 欧美黑人巨大xxxxx| 午夜福利片手机在线播放| 日韩国产亚洲高清在线久草| 丰满人妻中伦妇伦精品app| 国产三级久久久精品麻豆三级| 亚洲一码二码三码精华液| 亚洲成av人在线观看网站| 亚洲午夜福利在线观看| 桃花综合久久久久久久久久网| 久久国产精品老女人| 大肉大捧一进一出好爽| 国产在线 | 欧洲| 国产精品丝袜亚洲熟女| 一区二区传媒有限公司| 国产亚洲精品久久久久久大师| 亚洲无av码在线中文字幕| 国产精品一区二区高清在线|