在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ETFB Antibody

ETFB Antibody

  • 中文名稱：
    ETFB兔多克隆抗體
  • 貨號：
    CSB-PA267720
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA267720(ETFB Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA267720(ETFB Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: LoVo cells, Hela cells, Primary antibody: CSB-PA267720(ETFB Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    ETFB
  • 別名：
    Beta ETF antibody; Beta-ETF antibody; Electron transfer flavoprotein beta polypeptide antibody; Electron transfer flavoprotein beta subunit antibody; Electron transfer flavoprotein subunit beta antibody; Electron transferring flavoprotein beta polypeptide antibody; etfB antibody; ETFB_HUMAN antibody; FP585 antibody; MADD antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human ETFB
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (Probable). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. ETFB binds an AMP molecule that probably has a purely structural role.
  • 基因功能參考文獻：
    1. We identified and replicated a novel gene, ETFB, strongly associated with chronic anthracycline-induced cardiotoxicity independently of age at tumor onset and related to anthracycline-mediated mitochondrial dysfunction PMID: 28913729
    2. These results suggested that increasing levels of ATP5B and ETFB were associated with worsening renal injury. PMID: 27840937
    3. the findings of our present study suggest that ETFbeta plays an important role in renal tubular cell apoptosis during the progression of DN. PMID: 27035869
    4. Electron Transfer Flavoprotein Subunit Beta Is a Candidate Endothelial Cell Autoantigen in Behcet's Disease PMID: 25915519
    5. Human METTL20 is a mitochondrial lysine methyltransferase that targets ETFbeta and modulates its activity. PMID: 25416781
    6. ETFB knockdown can affect TGF-beta-induced tissue remodeling and/or fibrotic processes in vitro. PMID: 23068445
    7. Point mutations in electron-transfer-flavoprotein beta is associated with destabilized conformations and defective protein:protein interactions leading to mitochondrial dysfunction. PMID: 22588007
    8. ETFB participates in the mechanoregulation of fibroblast cell number in collagen gel culture. PMID: 21903359
    9. non-productive conformation stabilization underpins rapid electron transfer to electron-transferring flavoprotein PMID: 15975918
    10. Tissue samples from 16 unrelated patients with ETF deficiency were analysed, two of them harboured mutations in the ETFB gene. PMID: 16510302
    11. conformational and stability properties of the disease-causing variant ETFbeta-D128N, and our findings on the effect of flavinylation in modulating protein conformational stability and activity. PMID: 19088074

    顯示更多

    收起更多

  • 相關疾病：
    Glutaric aciduria 2B (GA2B)
  • 亞細胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    ETF beta-subunit/FixA family
  • 組織特異性：
    Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas.
  • 數據庫鏈接：

    HGNC: 3482

    OMIM: 130410

    KEGG: hsa:2109

    STRING: 9606.ENSP00000346173

    UniGene: Hs.348531



主站蜘蛛池模板： 国内精品人妻无码久久久影院| 狠狠躁18三区二区一区| 激情内射日本一区二区三区| 国产高清av在线播放| 国产精品亚洲二区在线播放| 久久精品av一区二区免费| 亚洲色成人网站www永久| 久久亚洲a片com人成| 99久久久无码国产精品动漫| 国产果冻豆传媒麻婆| 精品卡一卡二卡3卡高清乱码| 亚洲香蕉成人av网站在线观看| 欧洲免费无线码在线一区| 亚洲国产成人精品无码区蜜柚| 成人乱码一区二区三区av| 色妺妺视频网| 久久久久久久久久久国产| 亚洲中文字幕乱码av波多ji| 精品伊人久久久大香线蕉下载| 久久久亚洲欧洲日产国码aⅴ| 国产人澡人澡澡澡人碰视频| 国产精品亚洲精品日韩己满十八小| 国产超碰人人做人人爱一二区视品| 亚洲老熟女性亚洲| 亚洲日韩中文无码久久| 国产蜜芽尤物在线一区| 人妻熟妇乱又伦精品视频无广告| 亚洲欧美国产精品专区久久| 色综合久久久无码中文字幕| 国产成人亚洲综合无码品善网| 久久久久久无码午夜精品直播| 人人爽人人爽人人爽人人片av| 日本丰满熟妇乱子伦| 中日产幕无线码一区| 人妻色综合网站| 日本一二免费不卡区| 日韩欧美精品有码在线 | 在线播放免费人成视频在线观看| 久久9精品区-无套内射无码| 在线精品亚洲一区二区| 拍摄av现场失控高潮数次|