在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ENSA Antibody

ENSA Antibody

  • 中文名稱：
    ENSA兔多克隆抗體
  • 貨號：
    CSB-PA007686GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    ENSA
  • 別名：
    ENSAAlpha-endosulfine antibody; ARPP-19e antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human ENSA
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC,IF
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.
  • 基因功能參考文獻：
    1. The extended S phase in Ensa-depleted cells is completely rescued by the overexpression of Treslin. PMID: 28785014
    2. Taken together our results suggest a hierarchy of phosphatases coordinating Greatwall, Ensa/ARPP19 and Cdk substrate dephosphorylation during mitotic exit. PMID: 24391510
    3. Overexpressed ENSA suppresses tumor growth in an established hepatic cell line whereas hypermethylated ENSA might help maintain liver cancer initiating cells. PMID: 24211627
    4. The considerably decreased alpha-endosulfine could result in the continuous opening of K(ATP) channels and the subsequent decrease of neurotransmitters release associated with cognition in Down Syndrome. PMID: 11771735
    5. We mapped ENSA in silico to chromosome 1q21 near a confirmed type 2 diabetes susceptibility locus, and derived the genomic structure of four exons and three introns. PMID: 14728986
    6. The ENSA gene on 1q21 produces several alternatively spliced transcripts, and is located within a region linked with T2DM in diverse populations including the Pima Indians PMID: 14728987

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Endosulfine family
  • 組織特異性：
    Widely expressed with high levels in skeletal muscle and brain and lower levels in the pancreas.
  • 數據庫鏈接：

    HGNC: 3360

    OMIM: 603061

    KEGG: hsa:2029

    UniGene: Hs.632456



主站蜘蛛池模板： 黑人巨大白妞出浆| 亚洲不乱码卡一卡二卡4卡5| 亚洲美女高清无水av| 成人免费大片黄在线观看com| 韩国三级中文字幕hd| 狼色精品人妻在线视频| 国精产品999一区二区三区有限| 国产高清露脸孕妇系列| 午夜福利伦伦电影理论片在线观看 | 毛片大全真人在线| 午夜免费男女aaaa片| 国产综合在线观看| 国产末成年av在线播放| 国产成人精品日本亚洲成熟| 欧美拍拍视频免费大全| 天天燥日日燥| 久久亚洲人成电影网| 伊人久久精品无码二区麻豆| 色 亚洲 日韩 国产 综合| 在线日产精品一区| 精品综合久久久久久97| 日日碰狠狠躁久久躁婷婷| 久久久久久久久免费看无码| 变态另类牲交乱| 天天狠天天透天天伊人| 老鸭窝视频在线观看| 亚洲大尺度无码无码专线| av中文字幕无码免费看| 一本色道无码不卡在线观看| 亚洲精品国产av成拍色拍个| 久久无码精品一一区二区三区| 欧美肥婆姓交大片| 黑巨人与欧美精品一区| 欧美成人精品三级网站视频| 国产精品视频一区二区噜噜| 国产精品久久精品国产| 亚洲成片在线观看12345| 少妇被多人c夜夜爽爽| 人人做人人爽人人爱| 久久无码人妻国产一区二区| 综合亚洲桃色第一影院|