在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

ENPEP Antibody

  • 中文名稱:
    ENPEP兔多克隆抗體
  • 貨號:
    CSB-PA007678GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Aminopeptidase A antibody; AMPE_HUMAN antibody; AP-A antibody; APA antibody; bp-1 antibody; bp1 antibody; CD249 antibody; Differentiation antigen gp160 antibody; EAP antibody; Enpep antibody; Glutamyl aminopeptidase (aminopeptidase A) antibody; Glutamyl aminopeptidase antibody; Gp160 antibody; Ly51 antibody
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human ENPEP
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II.
  • 基因功能參考文獻:
    1. We suggest that APA enzymatic activity affects tumor initiation and cancer malignancy in a TWIST-dependent manner PMID: 28177885
    2. The substrate Angiotensin II, the enzymes aminopeptidases-A, B, M as well as IRAP were detected in the jejunal mucosa. PMID: 26311161
    3. This study suggests a role for GAP in the neoplastic development of renal tumours and provides additional data for considering the activity and expression of this enzyme of interest in the diagnosis and prognosis of renal neoplasms. PMID: 24885240
    4. These results explain the calcium-modulated substrate specificity of APA in central hypertension regulation PMID: 23888046
    5. There was no significant alteration in plasma APA activity in the patients with Chagas disease or dilated cardiomyopathies, as compared with that in health controls PMID: 21697726
    6. Rieger syndrome with microdeletions including only the PITX2 and ENPEP (glutamyl aminopeptidase) genes. PMID: 17850355
    7. Data show that APA appears to be an essential enzyme in the control of blood pressure via degradation of Angiotensin II. PMID: 17990103
    8. Data show that aminopeptidase A (APA) plays important roles in the regulation of blood pressure under both the physiological and pathological conditions. PMID: 17999179
    9. Data show that brain aminopeptidases act upon Ang I, Ang II and Ang III in order to activate brain AT(1) receptors. PMID: 18188697
    10. rare and common variation in ENPEP may contribute to the development of renal and hypertensive disorders and warrants further study PMID: 18206321
    11. The presence of APA in several human brain nuclei sensitive to angiotensins and involved in blood pressure regulation suggests that APA in humans is an integral component of the brain renin angiotensin system. PMID: 18410507
    12. A novel nonsense polymorphism in the aminopeptidase-a gene was associated with hypertension among postmenopausal women, and those with marginal calcium and vitamin D intake. PMID: 18550936
    13. Angiotensin III and aminopeptidase A and N, related converting enzymes, contribute to cell proliferation of prostate cancer and may be implicated in cancer progression. PMID: 18677709
    14. Over-expressed APA drastically reduces, in a calcium dependent manner, full-length-Abeta but not amyloid-beta precursor protein (APP) intracellular domain in a cell-free model of Abeta production. PMID: 19187443
    15. The activity of glutamyl aminopeptidase was significally increased in head and neck squamous cell carcinoma tissue. PMID: 19373777

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type II membrane protein.
  • 蛋白家族:
    Peptidase M1 family
  • 組織特異性:
    Expressed in choriocarcinoma cancer cell lines (at protein level). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.
  • 數據庫鏈接:

    HGNC: 3355

    OMIM: 138297

    KEGG: hsa:2028

    STRING: 9606.ENSP00000265162

    UniGene: Hs.435765



主站蜘蛛池模板: 在线看片免费人成视频福利| 国内少妇毛片视频| 亚洲色无码专区在线播放| 欧美xxxx做受欧美| 丰满少妇呻吟高潮经历| 国产成人一区二区精品视频| 成人天堂婷婷青青视频在线观看 | 日本亚洲欧美日韩国产ay| 无码无遮挡又大又爽又黄的视频 | 天天做天天爱天天综合网2021| 亚洲精品黑牛一区二区三区| 久久爱www人成狠狠爱综合网| 少妇高潮毛片色欲ava片 | 国语自产偷拍精品视频蜜芽| 日日av色欲香天天综合网| 国产成人精品一区二区秒拍| 天下第一社区视频www日本| 国产亚洲欧美另类一区二区| 公么大龟弄得我好舒服秀婷视频| 国产成人综合亚洲看片| 香蕉在线精品视频在线| 非洲黑人最猛性xxxx交| 国产精品激情| 2019一級特黃色毛片免費看| 国产成人高清精品免费| 无码精品a∨在线观看无广告| 午夜福利视频| 亚洲 熟女 久久 国产| 18禁超污无遮挡无码免费网站国产| 国产女人高潮嗷嗷嗷叫| 国偷自产一区二区免费视频| 99精品视频九九精品视频| 好爽又高潮了毛片免费下载| 中文字幕精品视频在线看免费 | 欧美日韩在线视频| 毛片内射久久久一区| 色天使久久综合给合久久97色| 亚洲国产成人av网站| 亚洲综合一区无码精品| 乌克兰少妇videos高潮| av片在线观看永久免费|