在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ENPEP Antibody, Biotin conjugated

ENPEP Antibody, Biotin conjugated

  • 中文名稱：
    ENPEP兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA14759D0Rb
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ENPEP Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Aminopeptidase A antibody; AMPE_HUMAN antibody; AP-A antibody; APA antibody; bp-1 antibody; bp1 antibody; CD249 antibody; Differentiation antigen gp160 antibody; EAP antibody; Enpep antibody; Glutamyl aminopeptidase (aminopeptidase A) antibody; Glutamyl aminopeptidase antibody; Gp160 antibody; Ly51 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Glutamyl aminopeptidase protein (719-949AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II.
  • 基因功能參考文獻：
    1. We suggest that APA enzymatic activity affects tumor initiation and cancer malignancy in a TWIST-dependent manner PMID: 28177885
    2. The substrate Angiotensin II, the enzymes aminopeptidases-A, B, M as well as IRAP were detected in the jejunal mucosa. PMID: 26311161
    3. This study suggests a role for GAP in the neoplastic development of renal tumours and provides additional data for considering the activity and expression of this enzyme of interest in the diagnosis and prognosis of renal neoplasms. PMID: 24885240
    4. These results explain the calcium-modulated substrate specificity of APA in central hypertension regulation PMID: 23888046
    5. There was no significant alteration in plasma APA activity in the patients with Chagas disease or dilated cardiomyopathies, as compared with that in health controls PMID: 21697726
    6. Rieger syndrome with microdeletions including only the PITX2 and ENPEP (glutamyl aminopeptidase) genes. PMID: 17850355
    7. Data show that APA appears to be an essential enzyme in the control of blood pressure via degradation of Angiotensin II. PMID: 17990103
    8. Data show that aminopeptidase A (APA) plays important roles in the regulation of blood pressure under both the physiological and pathological conditions. PMID: 17999179
    9. Data show that brain aminopeptidases act upon Ang I, Ang II and Ang III in order to activate brain AT(1) receptors. PMID: 18188697
    10. rare and common variation in ENPEP may contribute to the development of renal and hypertensive disorders and warrants further study PMID: 18206321
    11. The presence of APA in several human brain nuclei sensitive to angiotensins and involved in blood pressure regulation suggests that APA in humans is an integral component of the brain renin angiotensin system. PMID: 18410507
    12. A novel nonsense polymorphism in the aminopeptidase-a gene was associated with hypertension among postmenopausal women, and those with marginal calcium and vitamin D intake. PMID: 18550936
    13. Angiotensin III and aminopeptidase A and N, related converting enzymes, contribute to cell proliferation of prostate cancer and may be implicated in cancer progression. PMID: 18677709
    14. Over-expressed APA drastically reduces, in a calcium dependent manner, full-length-Abeta but not amyloid-beta precursor protein (APP) intracellular domain in a cell-free model of Abeta production. PMID: 19187443
    15. The activity of glutamyl aminopeptidase was significally increased in head and neck squamous cell carcinoma tissue. PMID: 19373777

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type II membrane protein.
  • 蛋白家族：
    Peptidase M1 family
  • 組織特異性：
    Expressed in choriocarcinoma cancer cell lines (at protein level). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 3355

    OMIM: 138297

    KEGG: hsa:2028

    STRING: 9606.ENSP00000265162

    UniGene: Hs.435765



主站蜘蛛池模板： 国产影片中文字幕| 欧美怡红院免费全部视频| 中文字幕人成乱码熟女免费| 中文字日产幕乱五区| 99精品国产一区二区| av色国产色拍| 800av凹凸视频在线观看| 国产熟妇按摩3p高潮大叫| 日本亚洲色大成网站www| 少妇夜夜春夜夜爽试看视频| 无码av片在线观看免费| 特黄做受又粗又大又硬老头| 国产伦精品一区二区三区免费| 精品久久久久久无码免费| 国产毛片毛多水多的特级毛片| 国产成人久久久精品二区三区| 久久久久久久综合狠狠综合| 精品国产三级在线观看| 狠狠色噜噜狠狠色综合久| 国产97色在线 | 日| 国产在线视频一区二区三区98 | 无码乱肉视频免费大全合集| 在线亚洲人成电影网站色www| 国产97在线 | 中文| 性欧美疯狂xxxxbbbb| 国产三级精品三级在线专1| 99re6这里有精品热视频| 韩国理伦片一区二区三区在线播放| 狠狠cao2020高清视频| 无码午夜人妻一区二区不卡视频| 8888四色奇米在线观看| 蜜臀aⅴ国产精品久久久国产老师 日韩一区二区三区精品 | 色狠狠色噜噜av天堂一区| 亚洲精品一区二区不卡| 久久www免费人成看片入口| 无码精品人妻一区二区三区影院 | 亚洲成av人片在一线观看| 久久久久国产精品人妻aⅴ牛牛| 影音先锋啪啪av资源网站| 国产欧美精品区一区二区三区| 亚洲精品92内射|